Abstract
Studies on the response of the central nervous system to injury generally require the use of two populations of animals — control and experimental. This places a premium on the choice of an experimental system which is sufficiently well defined to permit unequivocal conclusions that any changes are the result of the experimental manipulation rather than the natural variability of the system.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bennett MR, Raftos J (1977) The formation and regression of synapses during reinnervation of axolotl-striated muscles. J Physiol (London) 265: 261–295
Bernstein JJ, Bernstein ME (1973) Neuronal alteration and reinnervation following axonal regeneration and sprouting in mammalian spinal cord. Brain Behav Evol 8: 135–161
Burke RE, Walmsley B, Hodgson JA (1979) Structural-functional relation in monosynaptic action on spinal motoneurons. In: Brooks V, Asanuma H (eds) Integration in the nervous system. Igaku: Shoin, Tokyo, pp 27–45
Cope TC, Nelson SG, Mendell LM (1980) Factors outside the nauraxis mediate the “acute” increase in EPSP amplitude caudal to spinal cord transection. J Neurophysiol 44: 174–183
Cotman C, Nadler JV (1978) Reactive synaptogenesis in the hippocampus. In: Cotman C (ed) Neuronal plasticity. Raven Press, New York, pp 227–271
Dennis MJ, Yip JW (1978) Formation and elimination of foreign synapses on adult salamander muscle. J Physiol (London) 274: 299–310
Gallego R, Kuno M, Nunez R, Snider WD (1979) Disuse enhances synaptic efficacy in spinal moto-neurones. J Physiol (London) 291: 191–205
Goldberger ME, Murray M (1978) Recovery of movement and axonal sprouting may obey some of the same laws. In: Cotman C (ed) Neuronal plasticity. Raven Press, New York, pp 73–96
Kuno M, Llinas R (1970) Alterations of synaptic action in chromatolysed motoneurones of the cat. J Physiol (London) 210: 823–838
Matthews PBC (1972) Mammalian muscle receptors and their central actions Williams and Wilkins, Baltimore
McLaughlin B (1972) Propriospinal and supraspinal projections to motor nuclei of the cat spinal cord. J Comp Neurol 144: 475–500
Mendell LM, Henneman E (1971) Terminals of single la fibers: location, density and distribution within a pool of 300 homonymous motoneurons. J Neurophysiol 34: 171–187
Mendell LM, Munson JB, Scott JG (1976) Alterations of synapses on axotomized motoneurons. J Physiol (London) 255: 67–79
Munson JB, Sypert GW (1979) Properties of single fibre excitatory postsynaptic potentials in triceps surae motoneurons. J Physiol (London) 296: 329–342
Murray M, Goldberger ME (1974) Redistribution of function and collateral sprouting in the cat spinal cord: the partially hemisected animal. J Comp Neurol 158: 19–36
Nelson SG, Mendell LM (1979) Enhancement in Ia-motoneuron synaptic transmission caudal to chronic spinal cord transection. J Neurophysiol 42: 642–654
Nelson SG, Collatos TC, Niechaj A, Mendell LM (1979) Immediate increase in la-motoneuron synaptic transmission caudal to spinal cord transection. J Neurophysiol 42: 665–664
Pullen AH, Sears TA (1978) Modification of “C” synapses following partial central deafferentation of thoracic motoneurons. Brain Res 145: 141–146
Rall W (1967) Distinguishing theoretical synaptic potentials for different soma-dendritic distributions of synaptic input. J Neurophysiol 30: 1168–1193
Redman SJ (1976) A quantitative approach to the integrative function of dendrites. In: Porter R (ed) International review of physiology: Neurophysiology, vol 10. University Park Press, Baltimore, pp 1–36
Roper S (1976) The acetylcholine sensitivity of the surface membrane of multiply-innervated parasympathetic ganglion cells in the mudpuppy before and after partial denervation. J Physiol (London) 254: 455–473
Scott JG, Mendell LM (1976) Individual EPSPs produced by single triceps surae Ia afferent fibers in homonymous and heteronymous motoneurons. J Neurophysiol 39: 679–692
Sharpless SK (1975) Supersensitivity-like phenomena in the central nervous system. Fed Proc 34: 1990–1997
Strick PL, Burke RE, Kanda K, Kim CC (1976) Tracing spinal neurons projecting to the ventral horn using retrograde transport: possible last order interneurons to medial gastrocnemius moto-neurones. Neurosci Abstr 1: 170
Tsukahara N (1978) Synaptic plasticity in the red nucleus. In: Cotman C (ed) Neuronal plasticity. Raven Press, New York, pp 113–130
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Mendell, L.M., Nelson, S.G., Cope, T.C., Cope, T.C. (1981). Functional Synaptic Changes Caudal to Spinal Cord Transection. In: Flohr, H., Precht, W. (eds) Lesion-Induced Neuronal Plasticity in Sensorimotor Systems. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68074-8_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-68074-8_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-68076-2
Online ISBN: 978-3-642-68074-8
eBook Packages: Springer Book Archive