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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 53))

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Abstract

The history of the study of ganglionic substances begins with the paper of Langley and Dickinson (1889), who established the ability of nicotine to block the neurones in the superior cervical ganglion. This was a considerable discovery as the authors ascertained that impulses were transmitted from pre- to postganglionic neurones in the autonomic ganglia. Simultaneously they indicated the possibility of pharmacological influence upon interneuronal transmission in autonomic ganglia. The idea of ganglionic receptors specificallv sensitive to nicotine followed losicallv.

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References

  • Acheson, G.H., Moe, G.K.: The action of tetraethylammonium ion on the mammalian circulation. J. Pharmac. exp. Ther., 87, 220–236 (1946a)

    CAS  Google Scholar 

  • Acheson, G.H., Pereira, S.A.: The blocking effect of tetraethylammonium ion on the superior cervical ganglion of the cat. J. Pharmac. exp. Ther., 87, 273–280 (1946b)

    CAS  Google Scholar 

  • Barlow, R.B.: Introduction to chemical pharmacology, 2nd ed. England: Methuen 1968

    Google Scholar 

  • Bein, H.J., Meier, R.: Zur Pharmakologie des N,N,N′, N′-3-pentamethyl-N-N′-diäthyl-3-azapentan-1,5-diammonium dibromid (CrBa 9295), ein ganglionär hemmende Substanz. Experientia, 6 351–356 (1950)

    Article  PubMed  CAS  Google Scholar 

  • Bikov, K.M.: Brain cortex and visceral organs. p. 330. Kirov: VMMA 1942 (Russ.)

    Google Scholar 

  • Birks, R.J., Mcintosh, F.C.: Acetylcholine metabolism of a sympathetic ganglion. Canad. J. Biochem., 39, 787–827 (1961)

    Article  CAS  Google Scholar 

  • Dolivo, M.: Metabolism of mammalian sympathetic ganglia. Fed. Proa, 33, 1043–1048 (1974)

    CAS  Google Scholar 

  • Dolivo, M., Routiller, C.: Changes in ultrastructure and synaptic transmission in the sympathetic ganglion during various metabolic condition. In: Mechanisms of synaptic transmission. Progr. Brain Res., 31, 111–123 (1969)

    Chapter  Google Scholar 

  • Eccles, J.C.: The neurophysiological basis of mind. Oxford: Clarendon press 1953

    Google Scholar 

  • Eccles, J.C.: The physiology of nerve cells. Baltimore: The John Hopkins press 1957

    Google Scholar 

  • Feldberg, W., Gaddum, J.H.: The chemical transmission at synapses in a sympathetic ganglion. J. Physiol., 81, 305–319 (1934)

    PubMed  CAS  Google Scholar 

  • Gyermek, L.: Ganglionic stimulant and depressant agents. In: Drugs affecting the peripheral nervous system, 1, 149–326. Ed. by Burger, A. New-York: Dekker 1967

    Google Scholar 

  • Haefely, W.: Electrophysiology of the adrenergic neuron. In: Handbook exp. Pharmacol., 33, 661–725. Berlin: Springer 1972

    Google Scholar 

  • Kharkevich, D.A.: Ganglionic agents. Moskva: Medgiz 1962 (Russ.)

    Google Scholar 

  • Kharkevich, D.A.: Ganglion-blocking substances in a series of bis-quaternary salts of the dialkylaminoalkyl esters of N-methyl-pyrrolidine carboxylic acid. Farmakol. i toxicol., 26, 172–179 (1963) (Russ.)

    CAS  Google Scholar 

  • Kharkevich, D.A.: Ganglion-blocking and ganglion-stimulating agents. Oxford: Pergamon Press 1967 (translation from Russian edition, 1962)

    Google Scholar 

  • Kharkevich, D.A. (ed.): New curariform and ganglion-blocking agents. Moskva: Meditsina 1970 (Russ.)

    Google Scholar 

  • Klupp, H.: Pharmakologische Untersuchung eines neuen Ganglionblockers mit langer Wirkungsdauer, N-(γ-Trimethylammoniumpropyl)-N-methylcamphidinium-dimethylsulfat (Ha-106). Arzneimittel-Forsch., 7, 2, 123–128 (1957)

    CAS  Google Scholar 

  • Langley, J.H.: On the reaction of cells and of nerve endigs to certain poisons chiefly as regards the reaction of striated muscle to nicotine and curare. J. Physiol., 33, 374–413 (1905)

    PubMed  Google Scholar 

  • Langley, J.H.: Croonian lecture. On nerve endings and on special exitable substances in cells. Proc. Roy. Soc., ser. B., 78, 170–194 (1906)

    Article  CAS  Google Scholar 

  • Langley, J.H.: The autonomic nervous system. London 1921

    Google Scholar 

  • Langley, J.H., Dickinson, W.L.: On the local paralysis of the peripheral ganglia and on the connexion of different classes of nerve fibres with them. Proc. Roy. Soc. (London), 46, 423–431(1889)

    Article  Google Scholar 

  • Larrabee, M.G.: Oxygen consumption of excised ganglia at rest and in activity. J. Neurochem., 2, 81–101 (1958)

    Article  PubMed  CAS  Google Scholar 

  • Larrabee, M.G.: Glucose metabolism in ganglia and nerves. In: Biophysics of physiological and pharmacological actions, 199–213 (1961)

    Google Scholar 

  • Larrabee, M.G.: Trans-synaptic stimulation of phosphatidylinositol metabolism in sympathetic neurons in situ. J. Neurochem., 15, 803–808 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Little, D.M.: Controlled hypotension in anesthesia and surgery. Springfield 1956

    Google Scholar 

  • McBride, W.J., Klingman, J.D.: Effects of excitation on the metabolism of a simple neuronal system: The mammalian sympathetic ganglion. In: Progress in neurobiology, 3, 253–287. Ed. by G.A. Kerkut and J.W. Philips. Oxford: Pergamon 1974

    Google Scholar 

  • Mcintosh, F.C., Collier, B.: Neurochemistry of cholinergic terminals. In: Neuromuscular junction. Ed. by E. Zaimis. Handbook of exp. Pharmacol., 42, 99–228. Berlin: Springer 1976

    Google Scholar 

  • Mashkovsky, M.D., Rabkina, L.E.: Pharmacological properties of the alkaloid pachicarpine. Farmakol. i toxicol., 15, 23–31 (1952) (Russ.)

    Google Scholar 

  • Nâdor, R.: Ganglienblocker. In: Progress in drug research, 2, 298–416 (1960)

    Google Scholar 

  • Osipov, V.P.: Artificial hypotension. Moskva: Medgiz 1967 (Russ.)

    Google Scholar 

  • Paton, W.D.M., Zaimis, E.J.: Clinical potentialities of certain bis-quaternary salts causing neuromuscular and ganglionic block. Nature (London), 162, 810 (1948)

    Article  CAS  Google Scholar 

  • Paton, W.D.M., Zaimis, E.J.: The methonium compounds. Pharmacol. Rev., 4, 3, 219–253 (1952)

    PubMed  CAS  Google Scholar 

  • Plummer, A.J., Trapold, I.H., Schneider, J.A., Maxwell, R.A., Earl, A.E.: Ganglionic blockade by a new bis-quaternary series including chlorisondamine dimethochloride. J. Pharmacol., exp. Ther., 115, 2, 173–184(1955)

    Google Scholar 

  • Randall, L.O., Peterson, W.G., Lehmann, G.: The ganglion blocking action of thiophanium derivatives. J. Pharmacol., exp. Ther., 97, 48–57 (1949)

    CAS  Google Scholar 

  • Sharapov, I.M.: Pharmacology of ganglion-blocking agents, Dicolinum. Farmakol. i Toxicol., 22, 1, 19–24 (1958) (Russ.)

    Google Scholar 

  • Sharapov, I.M.: Pharmacology of Dimecolinum, a new ganglion-blocking agents. Farmakol. i Toxicol., 25, 5, 533–538 (1962) (Russ.)

    CAS  Google Scholar 

  • Skok, V.I.: Physiology of autonomic ganglia. Leningrad: Izdatelstvo “Nauka” 1970 (Russ.) and Tokyo: Igaku Shoin 1973 (translation from Russian edition, 1970)

    Google Scholar 

  • Spinks, A., Young, E.H.P., Farrington, J.A., Dunlop, D.: The pharmacological actions of pempidine and its ethyl homologue. Brit. J. Pharmacol., 13, 501–520 (1958)

    PubMed  CAS  Google Scholar 

  • Syrneva, Yu. I.: Pharmacology of the alkaloids from the plant Nanophyton. Farmakol. i Toxicol., 13, 2, 26–28 (1950) (Russ.)

    Google Scholar 

  • Stone, C.A., Torchiana, M.L., Navarro, A., Beyer, K.H.: Ganglionic blocking properties of 3-methyl-amino-isocamphane hydrochloride (mecamylamine): A secondary amine. J. Pharmacol exp. Ther., 117, 2, 169–183 (1956)

    PubMed  CAS  Google Scholar 

  • Trĉka, V., Vanêĉek, M.: Nektere nove typy ganglioplegic. Ceskoslov. Farmacie, 8, 6, 316–326 (1959)

    Google Scholar 

  • Trendelenburg, U.: Some aspects of the pharmacology of autonomic ganglion cells. Ergebn. der Physiol., 59, 1–85(1967)

    Google Scholar 

  • Vysotskaja, N.B.: Effect of gangliolytics on phosphoric fractions in the superior cervical ganglion. Farmakol i Toxicol., 20, 2, 12–15 (1957) (Russ.)

    Google Scholar 

  • Vysotskaja, N.B.: Effects of ganglion-blocking substances on glycolytic processes in the superior cervical ganglion. Farmakol. i toxicol., 23, 2, 155–158 (1960) (Russ.)

    Google Scholar 

  • Vysotskaja, N.B.: Effects of ganglion-blocking substances on metabolic processes connected with transmission in the superior cervical ganglion. Doct. thesis: Moskva 1963 (Russ.)

    Google Scholar 

  • Volle, R.L.: Muscarinic and nicotinic stimulant actions at autonomic ganglia. Int. encyclop. of Pharmacol and therap., 1, Sect. 12, Oxford: Pergamon press 1966

    Google Scholar 

  • Volle, R.L.: Ganglionic transmission. Ann. Rev. Pharmacol., 9, 135–146 (1969)

    Article  PubMed  CAS  Google Scholar 

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© 1980 Springer-Verlag Berlin Heidelberg

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Kharkevich, D.A. (1980). Introduction. In: Kharkevich, D.A. (eds) Pharmacology of Ganglionic Transmission. Handbook of Experimental Pharmacology, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67397-9_1

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  • DOI: https://doi.org/10.1007/978-3-642-67397-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67399-3

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