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Evaluation of Antineoplastic Activity: Requirements of Test Systems

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Antineoplastic and Immunosuppressive Agents Part I

Abstract

The primary objectives of test systems for the evaluation of antineoplastic agents include (a) the identification of new agents which may be active against clinical neoplasia, (b) the detailed investigation of the action of drugs on host-tumor parameters and of factors which may influence chemotherapeutic effectiveness, and (c) detailed pharmacologic, toxicologic, biochemical, virologic, immunologic, and other investigations of the basic mechanism of action of antitumor agents.

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Authors
  1. Abraham Goldin
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  2. Stephen Carter
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  3. Nathan Mantel
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Editors and Affiliations

  1. Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, 06510, USA

    Alan C. Sartorelli (Professor) (Professor)

  2. Laboratory of Chemical Pharmacology, National Cancer Institute, National Istitutes of Health, Bethesda, Maryland, 20014, USA

    David G. Johns M. D.

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Goldin, A., Carter, S., Mantel, N. (1974). Evaluation of Antineoplastic Activity: Requirements of Test Systems. In: Sartorelli, A.C., Johns, D.G. (eds) Antineoplastic and Immunosuppressive Agents Part I. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 38 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65678-1_2

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