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Coxsackie B Viruses and Human Heart Disease

  • Chapter
The Coxsackie B Viruses

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 223))

Abstract

A large number of viruses can cause infections of the heart. Among these are the enteroviruses, adenoviruses, retroviruses and even orthomyxoviruses (Clements 1993). Human viruses causing systemic infections have a viremic stage during which the heart may be exposed to infectious agents. Thus the presence of virus in the myocytes or the infiltrating immune cells is likely to be a more common event than suspected. However, clinically overt cases of heart disease following common viral infections are rare and may represent a small percentage of all viral heart infections. Of the numerous agents commonly infecting humans, enteroviruses and in particular coxsackie B viruses (CVB) have been the most closely scrutinised agents implicated in human heart disease. The aim of this review is to discuss the evidence for an etiologic link between enteroviruses and in particular CVB and human heart disease.

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Authors and Affiliations

  1. Department of Cardiological Sciences, St George’s Hospital Medical School, Cranmer Terrace, Tooting, London, SW17 0RE, UK

    C. Baboonian, M. J. Davies & W. J. McKenna

  2. Department of Medical Microbiology, St George’s Hospital Medical School, Cranmer Terrace, Tooting, London, SW17 0RE, UK

    J. C. Booth

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  4. W. J. McKenna
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Editors and Affiliations

  1. Department of Pathology and Microbiology, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, NE, 69198-6495, USA

    Steven Tracy Ph.D. (Professor) & Nora M. Chapman Ph.D. (Assistant Professor) (Professor) &  (Assistant Professor)

  2. National Center for Infectious Diseases, Centers for Disease Control and Prevention, Clifton Road, Atlanta, GA, 30333, USA

    Brian W. J. Mahy Ph.D., Sc.D. (Director of Viral and Rickettsial Diseases) (Director of Viral and Rickettsial Diseases)

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Baboonian, C., Davies, M.J., Booth, J.C., McKenna, W.J. (1997). Coxsackie B Viruses and Human Heart Disease. In: Tracy, S., Chapman, N.M., Mahy, B.W.J. (eds) The Coxsackie B Viruses. Current Topics in Microbiology and Immunology, vol 223. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60687-8_3

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  • DOI: https://doi.org/10.1007/978-3-642-60687-8_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64507-5

  • Online ISBN: 978-3-642-60687-8

  • eBook Packages: Springer Book Archive

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