Abstract
Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative disorder, first described as a separate entity in 1958 and named in 1966 for the characteristic leukemic cell cytoplasmic protrusions seen on light microscopy of peripheral blood and bone marrow smears [1]. Despite its rarity, HCL has been of great interest to hematologists because of the evolution of successful management which has increased survival time from a median of 53 months without treatment [2] to approximate that of an age-matched cohort.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bouroncle BA (1994) Thirty-five years in the progress of hairy cell leukemia. Leuk Lymphoma 14 [Suppl1]: 1–12
Golomb HM, Catovsky D, Golde DW (1978) Hairy cell leukemia: a clinical review based on 71 cases. Ann Intern Med 89: 677–693
Lauria F, Benfenati D, Raspadori D, Rondelli D, Zinzani L, Tura S (1993) High complete remission rate in hairy cell leukemia treated with 2-chlorodeoxyadenosine. Leuk Lymphoma 11: 399–404
Dann E J, Gillis S, Rachmilewitz A, Barak V, Cass Y, Ruchlemer R, Polliak A (1994) Hairy cell leukemia: results of 2-chlorodeoxyadenosine therapy in Jerusalem. Leuk Lymphoma 14 [Suppl 1]: 127–131
Golomb HM, Vardiman J (1993) Hairy cell leukemia. In: Holland JF, Frei E, Bast RC et al (eds) Cancer Medicine, 3rd edn. Lea and Febiger, Philadelphia
Kampmeier P, Spielberger R, Dickstein J, Mick R, Golomb HM, Vardiman JW (1994) Increased incidence of second neoplasms in patients treated with interferon α2b for hairy cell leukemia. A clinicopathological assessment. Blood 83: 2931–2938
Trussard X, Henry-Amar M, Flandrin G (1994) Second cancer risk after interferon therapy (letter)? Blood 84: 3242–3244
Golomb HM (1994) Do we know the treatment of choice for hairy cell leukemia? Ann Oncol 5: 676–677.
Spielberger RT, Mick R, Ratain MJ, Golomb HM (1994) Interferon treatment for hairy cell leukemia. An update on a cohort of 69 patients treated from 1983–1986. Leuk Lymphoma 14 [Suppl 1]: 89–93
Troussard X, Flandrin G (1994) Hairy cell leukemia. An update on a cohort of 93 patients treated in a single institution. Effects of interferon in patients relapsing after splenectomy and in patients with or without maintenance treatment. Leuk Lymphoma 14 [Suppl 1]: 99–105
Federico M, Frassoldati A, Lamparelli T et al (1994) Long-term results of alpha interferon as initial therapy and splenectomy as consolidation therapy in patients with hairy cell leukemia. Final report from the Italian Cooperative Group for HCL. Ann Oncol 5: 725–731
Pittaluga S, Verhoef G, Maes A, Boogaerts MA, De Wolf-Peeters C (1994) Bone marrow trephines; findings in patients with hairy cell leukemia before and after treatment. Histopathology 25: 129–135
Gutterman JU (1994) Cytokine therapeutics: lessons from interferon α. Proc Natl Acad Sci USA 91: 1198–1205
Rozenblum E, Larripa I, Barazzutti L, Rendo P, Avalos JS (1994) Interferon DNA polymorphism in chronic leukemia. Leuk Lymphoma 13: 99–103
Tallman MS, Hakimian D (1995) Purine nucleotide analogs: emerging roles in indolent lymphoproliferative disorders. Blood 86: 2463–2474
Saven A, Piro L (1994) Newer purine analogues for the treatment of hairy-cell leukemia. N Engl J Med 330: 691–697
Golomb HM, Dodge R, Mick R, Budman D, Hutchison R, Horning SJ, Schiffer CA (1994) Pentostatin treatment for hairy cell leukemia patients who failed initial therapy with recombinant alpha-interferon: a report of CALGB study 8515. Leukemia 8: 2037–2040
Annino L, Ferrari A, Giona F et al (1994) Deoxycoformycin induces long-lasting remissions in hairy cell leukemia: clinical and biological results of two different regimens. Leuk Lymphoma 14 [Suppl 1]: 115–119
Saven A, Piro LD (1993) Complete remissions in hairy cell leukemia with 2-chlorodeoxyadenosine after failure with 2’-deoxycoformycin. Ann Intern Med 119: 278–283
Piro LD, Carrera CJ, Carson DA, Beutier E (1990) Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine. N Engl J Med 322: 1117–1121
Piro LD, Ellison DJ, Saven A (1994) The Scripps Clinic experience with 2-chlorodeoxyadenosine in the treatment of hairy cell leukemia. Leuk Lymphoma 14 [Suppl 1]: 121–125
Tallman MS, Hakimian D, Dyrda S, Kiley C, Nemcek A, Peterson L (1994) Assessment of complete remission after 2-chlorodeoxyadenosine for hairy cell leukemia: utility of marrow immunostaining and measurement of splenic index. Leuk Lymphoma 14 [Suppl 1]: 133–138
Pileri S, Sabattini E, Poggi S et al (1994) Bone marrow biopsy in hairy cell leukemia patients. Histological and immunohistochemical analysis of 46 cases treated with different therapies. Leuk Lymphoma 14 [Suppl 1]: 67–71
Di Celle PF, Reato G, Raspadori D et al (1994) Molecular evaluation of clonal remission in hairy cell leukemia patients treated with 2-chlorodeoxyadenosine Leuk Lymphoma 14 [Suppl 1]: 139–142
Kraut EH (1994) Cross-resistance to purine analogs in hairy cell leukemia (letter). Ann Intern Med 120: 247–248
Kraut EH, Hoo GC (1991) Fludarabine phosphate in refractory hairy cell leukemia. Am J Hematol 37: 59–60
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zent, C.S., Golomb, H.M. (1997). Treatment Options for Hairy Cell Leukemia. In: Aul, C., Schneider, W. (eds) Interferons. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60411-9_9
Download citation
DOI: https://doi.org/10.1007/978-3-642-60411-9_9
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-61051-9
Online ISBN: 978-3-642-60411-9
eBook Packages: Springer Book Archive