Zusammenfassung
Mit der Alzheimer Demenz (AD) müssen wir heute und - aufgrund der steigenden Lebenserwartung - noch stärker in der Zukunft rechnen, mit den individuellen Schicksalen der Patienten ebenso wie mit der wirtschaftlichen Belastung (Souetre et al. , 1999). Wenn in allen anderen Bereichen der Medizin weiterhin so erfreuliche Fortschritte erzielt werden, so kann gerade dies zu einer Zunahme der Patienten mit „primär degenerativer“AD führen.
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Literatur
Albert E (1963) Senile Demenz und Alzheimer - die gleiche Krankheit? Zbl Ges Neurol Psychiat 172: 264
Alzheimer A (1907) Über eine eigenartige Erkrankung der Hirnrinde. Allg Z Psychiat 64: 146
Bertram L, Busch R, Spiegl et al. (1988) Paternal age as a risk factor for Alzheimer disease in the absence of a major gene. Neurogenetics 1: 277–280
Bobinski M, de Leon M, Convit A et al. (1999) MRI of entorhinal cortex in mild Alzheimers disease. Lancet 1: 38–39
Bowler JV, Munoz DG, Merskey H, Hachinski V (1998) Fallacies in the pathological confirmation of the diagnosis of Alzheimers disease. J Neurol Neurosurg Psychiatry 64: 18–24
Desgranges B, Baron JC, Sayette V de la et al. (1998) The neural substrates of memory systems impairment in Alzheimers disease. A PET study of resting brain glucose utilization. Brain 121: 611–631
Erkinjuntti T, Østbye T, Steenhuis R et al. (1997) The effect of different diagnostic criteria on the prevalence of dementia. N Engl J Med 337 (23): 1667–1674
Fabrigoule C, Roüch I, Taberly A et al. (1998) Cognitive process in preclinical phase of dementia. Brain 121: 135–141
Förstl H (1998) Alzheimers disease: the size of the problem, clinical manifestation and heterogeneity. J Neural Transm Suppl 54: 1–8
Förstl H, Jablenski (1999) Organisch bedingte psychische Störungen. Psychiatrie der Gegenwart. Bd. IV. Springer Berlin Heidelberg New York. pp. 1–12
Förstl H, Zerfass R, Geiger-Kabisch C et al. (1995) Brain atrophy in normal ageing and Alzheimers disease : Volumetrie discrimination and clinical correlations. Brit J Psychiat 167: 739–746
Fox NC, Warrington EK, Seiffer AL et al. (1998) Presymptomatic cognitive deficits in individuals at risk of familial Alzheimers disease. A longitudinal study. Brain 121: 1631–1639
Henon H, Pasquier F, Durieu I et al (1998) Medial temporal lobe atrophy in stroke patients: relation to preexisting dementia. J Neurol Neurosurg Psychiatry 65: 641–647
Hodges J (1998) The amnestic prodrome of Alzheimer’s disease. Editorial. Brain: 1601-1602
Holmes C, Cairns N, Lantos P, Mann A (1998) Validity of current clinical criteria for Alzheimers disease, vascular dementia and dementia with Lewy bodies. Br J Psychiatry 174: 45–50
Hyman BT, Trojanowski JQ (1997) Editorial on consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 56: 1095–1097
Kraepelin E (1910) Psychiatrie - ein Lehrbuch für Studierende und Ärzte. VIII. Aufl, Bd II, 1. Barth, Leipzig
Kurz A, Riemenschneider M, Buch K et al. (1998) Tau cerebrospinal fluid is signifkantly increased at the earliest clinical stage of Alzheimer disease. Alz Dis Assoc Dis 12: 372–377
Lauter H, Meyer JE (1968) Clinical and nosological concepts of senile dementia. In: Müller, Ciompi (eds) Senile Dementia. Hans Huber, Bern Stuttgart, pp 13–26
Masters CL, Beyreuther K (1998) Alzheimer’ disease. Science, medicine and the future. Brit Med J 316: 446–448
Minoshima S, Giordani B, Berent S et al. (1997) Metabolie Reduction in the posterior cingulate cortex in very early Alzheimer’s disease. Ann Neurol 42 (1): 85–94
Reiman EM, Uecker A, Caselli RJ et al. (1998) Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer’s disease. Ann Neurol 44 (2): 288–291
Snowdon DA, Greiner LH, Mortimer JA et al. (1997) Brain infaretion and the clinical expression of Alzheimer disease. The nun study. JAMA 277 (10): 813–817
Snowdon DA, Kemper SJ, Mortimer JA et al. (1996) Linguistic ability in early life and cognitive funetion and Alzheimer’s disease in late life. Findings from the nun study. JAMA 275 (7) 528–532
Stewart R (1998) Cardiovascular factors in Alzheimer’s disease. J Neurol Neurosurg Psychiat 65: 143–147
Souetre E, Thwaites RMA, Yeardley HL (1999) Economic impact of Alzheimer’s disease in the United Kingdom. Br J Psychiatry 174: 51–55
Troncoso JC, Cataldo AM, Nixon RA et al. (1998) Neuropathology of preclinical and clinical late-onset Alzheimer’s disease. Ann Neurol 43 (5): 673–676
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Förstl, H. (1999). Die Alzheimer Demenz - ein Problem mit Zukunft. In: Förstl, H., Bickel, H., Kurz, A. (eds) Alzheimer Demenz. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60228-3_1
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DOI: https://doi.org/10.1007/978-3-642-60228-3_1
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