Skip to main content

Human Sebocyte Culture

  • Chapter
ACNE and ROSACEA

Abstract

Several experimental animal models have been proposed for studying the physiology of the sebaceous gland and evaluating the sebum-inhibitory effect of antiacne drug candidates. However, no animal model was found to be predictive for assessing drug effects in man.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Guy R, Kealey T (1998) The organ-maintened human sebaceous gland. Dermatology 196: 16–20

    Article  PubMed  CAS  Google Scholar 

  • Karasek M, Charlton M (1977) Isolation and growth of rabbit and human sebaceous gland cells in cell culture. J Invest Dermatol 68: 234A

    Google Scholar 

  • Karasek MA, Charlton ME (1982) In vitro growth and serial cultivation of normal human sebaceous gland cells. Clin Res 30: 263A

    Google Scholar 

  • Kealy T, Lee CM, Thody AJ, Coaker T (1986) The isolation of human sebaceous glands and apocrine sweat glands by shearing. Br J Dermatol 114: 181–188

    Article  Google Scholar 

  • Kellum RE (1966) Isolation of human sebaceous glands. Arch Dermatol 93: 619–612

    Google Scholar 

  • Rosenfield RL, Deplewski D, Kentsis A, Ciletti N (1998) Mechanisms of androgen induction of sebocyte differentiation. Dermatology 196: 43–46

    Article  PubMed  CAS  Google Scholar 

  • Xia L, Zouboulis CC, Detmar M, Mayer da Silva A, Stadler R (1989) Isolation of human sebaceous glands and cultivation of sebacous gland-derived cells as an in vitro model. I Invest Dermatol 93: 314–321

    Article  Google Scholar 

  • Xia L, Zouboulis CC, Orfanos CE (1989) Isolation of human sebaceous glands and cultivation of cells presenting evidence for sebocytic differentiation in vitro. J Invest Dermatol 92: 544A

    Google Scholar 

  • Zouboulis CC, Korge B, Giannakopoulos G, Akamatsu H, Xia L, Schiller S, Gollnick H, Stadler R, Orfanos CE (1990) Cultured human sebocytes possess a characteristic pattern of sebocytic differentiation in vitro. J Invest Dermatol 95: 496A

    Google Scholar 

  • Zouboulis CC, Xia L, Akamatsu H, Seltmann H, Fritsch M, Hornemann S, Riihl R, Chen W, Nau H, Orfanos CE (1998) The human sebocyte culture model provides new insights into development and management of seborrhoea and acne. Dermatology 196: 21–31

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Plewig, G., Kligman, A.M. (2000). Human Sebocyte Culture. In: ACNE and ROSACEA. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59715-2_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59715-2_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66751-3

  • Online ISBN: 978-3-642-59715-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics