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Objektivierbarkeit und prognostische Faktoren des Krankheitsverlaufes der Multiplen Sklerose

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Multiple Sklerose

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Zusammenfassung

Der Krankheitsverlauf der Multiplen Sklerose ist höchst variabel und imEinzelfall oft nur schwer vorhersagbar. Dies hat insbesondere dann Relevanz, wenn außerhalb von plazebokontrollierten, randomisierten klinischen Studien für den einzelnen Patienten eine Aussage getroffen werden soll, inwieweit eine spezifische Therapie wirksam ist. Da heutzutagevor allem für die schubförmige Verlaufsform der Multiplen Sklerose (MS) zunehmend wirksamere Möglichkeiten der Immuntherapie zur Verfügung stehen (Rieckmann u. Toyka 1999), ist es erforderlich, an der Etablierung besserer Parameter zu arbeiten, die auch im klinischen Alltag eine objektive Einordnung der Befunde ermöglichen. Zudem fragen die Patienten auch bei Stellung der Erstdiagnose häufig schon an, welche Prognose die Erkrankung nun bei ihnen speziell hat. Dies ist verständlich, da es bei dem überwiegend betroffenen jungen Patientengut eine hohe Bedeutung für die weitere Berufs- und Lebensplanung hat. Im Folgenden werden die verfügbaren und etablierten Parameter zur Objektivierbarkeit des Krankheitsverlaufes zusammen mit prognostischen Faktoren aus der Zusatzdiagnostik dargestellt und kritisch diskutiert.

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Authors
  1. R. Gold
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  2. F. X. Weilbach
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Editors and Affiliations

  1. Klinik und Poliklinik für Neurologie, Universität Rostock, Gehlsheimer Str. 20, 18055, Rostock, Germany

    Uwe K. Zettl  & Eilhard Mix PhD  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Gold, R., Weilbach, F.X. (2001). Objektivierbarkeit und prognostische Faktoren des Krankheitsverlaufes der Multiplen Sklerose. In: Zettl, U.K., Mix, E. (eds) Multiple Sklerose. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59453-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-59453-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41121-5

  • Online ISBN: 978-3-642-59453-3

  • eBook Packages: Springer Book Archive

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