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Diagnostik und Therapie von Augenmotilitätsstörungen bei Multipler Sklerose

  • Conference paper
Multiple Sklerose

Zusammenfassung

Bei der Multiplen Sklerose (MS) kommt es zu verschiedenen herdneurologischen Defiziten, häufiger auch zu Augenmotilitätsstörungen aufgrund von Entmarkungsherden im Hirnstamm oder Kleinhirn. Sehr häufige Okulomotorikstörungen sind die internukleäre Ophthalmoplegie (INO), zerebelläre Augenmotilitätsstörungen (Blickrichtungsnystagmus, Rebound-Nystagmus, etc.), der erworbene Fixationspendelnystagmus (EFPN) und Sakkadenanomalien wie Latenzverlängerungen, -verlangsamungen und Dysmetrien (Barnes u. McDonald 1992; Frohman et al. 1997). Häufig sind Blickfolgesakkadierungen, horizontale und vertikale Blickparesen, vertikaler Fixationsnystagmus (Upbeat- und Downbeat-Nystagmus) sowie der zentrale Lagenystagmus. Selten kommt es zu sakkadischen Oszillationen (Ocular Flutter, Opsoklonus), periodisch alternierendem Nystagmus, Obliquus- superior-Myokymie und dem blickrichtungsabhängigen Blepharoklonus (Leigh u. Zee 1999). Aufgrund der besseren Auflösung der bildgebenden Diagnostik mit der Kernspintomografie und der Augenbewegungsregistrierungen, die mit Hilfe der Scleral-Coil-Technik und der Videookulografie jetzt auch dreidimensional möglich sind und die torsionelle Komponente mit berücksichtigen, gelang es, einige okulomotorische Syndrome weiter zu klären und deren topische Zuordnung im Hirnstamm und Kleinhirn herauszuarbeiten.

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Authors
  1. M. Dieterich
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  2. K. Jahn
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Editors and Affiliations

  1. Klinik und Poliklinik für Neurologie, Universität Rostock, Gehlsheimer Str. 20, 18055, Rostock, Germany

    Uwe K. Zettl  & Eilhard Mix PhD  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Dieterich, M., Jahn, K. (2001). Diagnostik und Therapie von Augenmotilitätsstörungen bei Multipler Sklerose. In: Zettl, U.K., Mix, E. (eds) Multiple Sklerose. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59453-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-59453-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41121-5

  • Online ISBN: 978-3-642-59453-3

  • eBook Packages: Springer Book Archive

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