Skip to main content
SpringerLink
Log in

Rare Primary Malignancies of the Liver

  • Chapter
Liver Malignancies

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Primary malignant neoplasms of the liver are classified by the cell of origin (Table 10.1). In this chapter, primary malignant liver tumors are discussed: hepatoblastoma, arising from hepatocytes; cysto-adenoma and cystoadenocarcinoma, arising from biliary cells; epithelioid hemangioendothelioma, angiosarcoma and other mesenchymal sarcomas, arising from mesenchymal tissue; and finally primary lymphoma, arising from lymphomatous tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Agildere AM, Haliloglu M, Akhan 0 (1991) Biliary cystadenoma and cystadenocarcinoma. AIR 156:1113

    Google Scholar 

  • Bacchi MM, Rabenhorst SH, Soares FA, et a1 (1996) AIDS-related lymphoma in Brazil. Histopathology, immunophenotype, and association with Epstein-Barr virus. Am J Clin Pathol 105:230–237

    PubMed  CAS  Google Scholar 

  • Bates SM, Keller MS, Ramos IM, et a1 (1990) Hepatoblastoma: detection of tumor vascularity with duplex Doppler US. Radiology 176:505–507

    PubMed  CAS  Google Scholar 

  • Boechat MI, Kanganlow H, Ortega J, et al (1988) Primary liver tumors in children: Comparison of CT and MR imaging. Radiology 169:727–732

    PubMed  CAS  Google Scholar 

  • Buetow PC, Midkiff RB (1997). Primary malignant neoplasms in the adult. MRI Clin North Am 5:289–318

    CAS  Google Scholar 

  • Buetow PC, Buck JL, Ros PR, et al (1994) Malignant vascular tumors of the liver: radiologie-pathologic correlation. RadioGraphics 14:153–166

    PubMed  CAS  Google Scholar 

  • Buetow PC, Buck JL, Pantongrag-Brown L, et a1 (1995) Biliary cystadenoma and cystadenocarcinoma: Clinical-imagingpathologic correlation with emphasis on the importance of ovarian stroma. Radiology 196:805–810

    PubMed  CAS  Google Scholar 

  • Castellino RA, Hoppe RI, Blank N, et al (1984) Computed tomography, lymphography and staging laparotomy in colon correlations in staging of Hodgkin disease. AIR 143:37–41

    CAS  Google Scholar 

  • Choi BL, Lim JH, Han MC, et a1 (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61

    PubMed  CAS  Google Scholar 

  • Clements D, Hubscher S, West R, et a1 (1986) Epithelioid hemangioendothelioma of the liver: a case report. J Hepatol 2:441–449

    Article  PubMed  CAS  Google Scholar 

  • Corrigan K, Semelka RC (1995) Dynamic contrast-enhanced MR imaging of fibrolamellar hepatocellular carcinoma. Abdom Imaging 20:122–125

    Article  PubMed  CAS  Google Scholar 

  • Craig JR, Peters RL, Edmondson HA (1989) Tumors of the liver and intrahepatic bile ducts. In: Atlas of tumor pathology, Second Series, Fascicle 26. Armed Forces Institute of Pathology, Washington DC

    Google Scholar 

  • Dachman АН, Parker RL, Ros PR, et al (1987) Hepatoblastoma: a radiologic-pathologic correlation in 50 cases. Radiology 164:15–19

    PubMed  CAS  Google Scholar 

  • Davey MS, Cohen MD (1996) Imaging of gastrointestinal malignancy in childhood. Radiol Clin North Am 34:717–742

    PubMed  CAS  Google Scholar 

  • Dean PJ, Haggitt RC, O’Hara CJ (1985) Malignant epithelioid hemangioendothelioma of the liver in young women: Relationship to oral contraceptive use. Am J Surg Pathol 9:695–704

    Article  PubMed  CAS  Google Scholar 

  • Eckstein RP, Ravich RMB (1986) Epithelioid hemangioendotheiioma of the liver: report of two cases histologically mimicking venoocciusive disease. Pathology 18:459–462

    Article  PubMed  CAS  Google Scholar 

  • Edmonson HA (1976) Benign epithelial tumors and tumorlike lesions of the liver. In: Okuda AA Peters RL (eds) Hepatocellular carcinoma. Wiley, New York, pp 309–330

    Google Scholar 

  • Enzinger FM, Weiss SW (1983) Soft-Tissue Tumors. Mosby Year-Book, St. Louis

    Google Scholar 

  • Freeney PC, Baron RL, Teefey SA (1992) Hepatocellular carcinoma: Reduced frequency of typical findings with dynamic contrast-enhanced CT in a non-Asian population. Radiology 182:143–148

    Google Scholar 

  • Friedburg H, Kauffmann GW, Bohm N, et al (1989) Sono-graphic and computed tomographic features of embryonal rhabdomyosarcoma of the biliary tract. Pediatr Radiol 14:436–438

    Article  Google Scholar 

  • Fukayama M, Nihei Z, Takizawa T, et al (1984) Malignant epithelioid hemangioendothelioma of the liver spreading throughout the hepatic veins. Virchows Arch A 404:275–287

    Article  CAS  Google Scholar 

  • Furui S, Itai Y, Ohtomo K, et al (1989) Hepatic epithelioid hemangioendothelioma: Report of five cases. Radiology 17 1:63–68

    Google Scholar 

  • Gates LK Jr, Cameron AJ, Nagorney DM, et al (1995) Primary leiomyosarcoma of the liver mimicking liver abscess. Am J Gastroenterol 90:649–652

    PubMed  Google Scholar 

  • Gazelle GS, Lee MJ, Hahn PF, et al (1994) US, CT and MRI of primary and secondary liver lymphoma. I Comput Assist Tomogr 18:412–415

    Article  CAS  Google Scholar 

  • Geoffray A, Couanet D, Montagne JP, et al (1987) Ultrasonography and computed tomography for diagnosis and follow-up of biliary duct rhabdomyosarcomas in children. Pediatr Radiol 17:127–131

    Article  PubMed  CAS  Google Scholar 

  • Ginaldi S, Bernadino M, Jing B, et al (1980) Ultrasonographic patterns of hepatic lymphoma. Radiology 136:427–431

    PubMed  CAS  Google Scholar 

  • Haaga JR, Lanzieri CF, Sartoris DJ, et al (1994) Computed Tomography and Magnetic Resonance Imaging of the Whole Body, 3rd edn. Mosby-Year Book, St. Louis, pp 909–919

    Google Scholar 

  • Harris AAAC;, Schwartz ML, Slasky BS, et al (1987) Post-trans-plantation cyclosporine-induced lymphoproliferative disorders: clinical and radiologic manifestations. Radiology 162:697–700

    PubMed  CAS  Google Scholar 

  • Horowitz ME, Etcubanas E, Webber BL, et al (1987) Hepatic undifferentiated (embryonal) sarcoma and rhabdomyosarcoma in children. Results of therapy. Cancer 59:396–402

    Article  PubMed  CAS  Google Scholar 

  • Ishak KG (1976) Mesenchymal tumors of the liver. In: Okuda K, Peter RL (eds) Hepatocellular Carcinoma. John Wiley & Sons, New York, pp 228–587

    Google Scholar 

  • Ishak KG (1987) Malignant mesenchymal tumors of the liver. In: Okuda K, Ishak KG (eds) Neoplasms of the Liver. Springer Verlag, New York, pp 121–156

    Google Scholar 

  • Ishak KG, Glunz PR (1967) Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases. Cancer 20:396–422

    Article  PubMed  CAS  Google Scholar 

  • Ishak KG, Willis GW, Cummins SD, et al (1977) Biliary cystadenoma and cystadenocarcinoma. Report of 14 cases and review of the literature. Cancer 39:322–338

    Article  PubMed  CAS  Google Scholar 

  • Itai Y, Teraoka T (1989) Angiosarcoma of the liver mimicking cavernous hemangioma on dynamic CT. I Comput Assist Tomogr 13:910–912

    CAS  Google Scholar 

  • Ito Y, Kojiro M, Nakashima T, et al (1988) Pathomorphologic characteristics of 102 cases of Thorotrast-related hepato-cellular carcinoma, cholangiocarcinoma, and hepatic angiosarcoma. Cancer 62:1153–1162

    Article  PubMed  CAS  Google Scholar 

  • Jaffe ES (1987) Malignant lymphoma: pathology of hepatic: involvement. Semin Liver Dis 7:257–268

    Article  PubMed  CAS  Google Scholar 

  • Kaude JV, Felman AU, Hawkins IF Jr (1980) Ultrasonography in primary hepatic tumors in early childhood. Pediatr Radiol 9:77–83

    CAS  Google Scholar 

  • Kojiro M, Nakashima T, Ito Y, et al (1985) Thorium dioxide-related angiosarcoma of the liver. Pathomorphic: tudy of 29 autopsy cases. Arch Pathol Lab Med 109:853–857

    PubMed  CAS  Google Scholar 

  • Korobkin MT, Stephens DH, Lee JKT, et al (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonoraphic findings. AIR 153:507–511

    CAS  Google Scholar 

  • List AF, Greco FA, Vogier LB (1987) Lymphoproliterative diseases in immunocompromised hosts: the role of Epstein-Barr virus. J Clin Oncol 5:1678–1689

    Google Scholar 

  • Locker GY, Doroshow JH, Swelling LA, et al (1979) The clinical features of hepatic angiosarcoma: a report of four cases and a review of the English literature. Medicine 58:48–63

    Article  PubMed  CAS  Google Scholar 

  • MacMahon HE, Murphy AS, Bates MI (1947) Endothelial-cell sarcoma of the liver following thorotrast injection:. Am J Pathol 23:585–611

    PubMed  CAS  Google Scholar 

  • Mahoney B, Jeffrey RB, Federle MP (1982) Spontaneous rupture of hepatic and splenic angiosarcoma demonstrated by CT. AIR 183:965–966

    Google Scholar 

  • Marti-Bonmati L, Ferrer D, Menor F, et al (1993) Hepatic mesenchymal sarcoma: MRI findings. Abdom ln-aging 18:176–179

    CAS  Google Scholar 

  • Miller JH (1981) The ultrasonographic appearance of cystic hyperplastoma. Radiology 138:141–143

    PubMed  CAS  Google Scholar 

  • Miller WI, Dodd GD, Federle MP, Baron RL (1992) Epithelioid hemangioendothelioma of the liver: imaging findings with pathologic correlation. AIR 159:53–57

    CAS  Google Scholar 

  • Murphy BJ, Casillas J, Ros PR, et al (1989) The CT appearance of cystic masses of the liver. RadioGraphics 9:307–312

    CAS  Google Scholar 

  • Nalesnik MA, Jatfe R, Starzl TE, et al (1988a) The patholc gy of posttransplant lymphoproliferative disorders occurring in the setting of cyclosporine A-prednisone immunosuppression. Am I Pathol 133:173–192

    CAS  Google Scholar 

  • Nalesnik MA, Makowka L, Starzl TE (1988b) The diagnosis and treatment of posttransplant lymphoproliferative disorders. Curr Prob! Surg 25:367–472

    Article  CAS  Google Scholar 

  • Nelson WE, Behrman RE, Kliegman RM, et al (1996) Nelson Textbook of Pediatrics, 15th edn. WB Saunders Company, Philadelphia, pp 1472–1473

    Google Scholar 

  • Nyberg DA, Jetfrey RB, Federle MP, et al (1986) Lymphomas: evaluation by abdominal CT. Radiology 159:59–63

    PubMed  CAS  Google Scholar 

  • Ohtomo K, Tsutomu A, Itai Y, et al (1992) MR imaging of malignant mesenchymal tumors of the liver. Gastrointest Radio! 17:58–62

    Article  CAS  Google Scholar 

  • Oliver JH (1996) Malignant hepatic neoplasms, excluding hepatocellular carcinoma and cholangiocarcinoma. In: Freeney (ed) Radiology of the liver, biliary tract, and I ancreas. American Roentgen Ray Society, U.S.A.

    Google Scholar 

  • Penn I, Hammond W, Brettschneider L, et al (1969) Malign ant lymphomas in transplantation patients. Transplant Proc 1:106–112

    PubMed  CAS  Google Scholar 

  • Penn I (1990) Cancers complicating organ transplantation (editorial) N Engl I Med 323:1767–1768

    CAS  Google Scholar 

  • Powers C, Ros PR, Stoupis C, et al (1994) Primary liver neoplasms: MR imaging with pathologic correlati:n. Radiographics 14:459–482

    PubMed  CAS  Google Scholar 

  • Radin DR, Craig JR, Colletti PM, et al (1988) Hepatic epithe- lioid hemangioendothelioma. Radiology 169:145–148

    PubMed  CAS  Google Scholar 

  • Ros PR (1994) Malignant liver tumors. In: Gore RM, Levine MS, Laufer I (eds) Gastrointestinal radiology. Saunders, Philadephia, pp 1897–1946

    Google Scholar 

  • Rosai J (1996) Ackerman’s Surgical Pathology, 8th ed. Mosby-Year Book, St. Louis, pp 903–913, 919–921

    Google Scholar 

  • Ryan J, Straus DJ, Lange C, et al (1988) Primary lymphoma of the liver. Cancer 61:370–375

    Article  PubMed  CAS  Google Scholar 

  • Sanders LM, Botet JF, Straus DJ, et al (1989) CT of primary lymphoma of the liver. AIR 152:973–976

    CAS  Google Scholar 

  • Sherlock S, Dooley J (1993) Diseases of the Liver and Biliary System, 9th edn. Blackwell Scientific Publications, Oxford, pp 44–61

    Google Scholar 

  • Shirkhoda A, Ros PR, Farah J, et al (1990) Lymphoma of the solid abdominal viscera. Radiol Clin North Am 28:785-799

    Google Scholar 

  • Silverman FN, Kuh JP (1993) In: Gaffey’s, Pediatric X-Ray Diagnosis: An Integrated Imaging Approach, 9th edn. Mosby-Year Book, St.Louis, pp 960–967

    Google Scholar 

  • Siskin GP, Haller JO, Miller S, et al (1995) AIDS-related lymphoma: Radiologic features in pediatric patients. Radiology 196:63–66

    PubMed  CAS  Google Scholar 

  • Smith WL, Franken EA, Mitros FA (1983) Liver tumors in children. Semin Roentgenol 18:136–148

    Article  PubMed  CAS  Google Scholar 

  • Stark DS, Bradley WG (1992) Magnetic Resonance Imaging, 2nd edn. Mosby-Year Book, St. Louis, pp 2093–2095

    Google Scholar 

  • Stephens DH, Johnson CD (1994) Primary malignant neoplasms of the liver. In: Freeny PC, Stevenson GW (eds) Margulis and Burhenne’s alimentary tract radiology. Mosby-Year Book, St. Louis, pp 1662–1687

    Google Scholar 

  • Tavares MH, Saracoca A, Oliveria EA, et al (1979) Thorium dioxide and the liver: updated clinical and biochemical findings. Environ Res 18:173–177

    Article  PubMed  CAS  Google Scholar 

  • Weissieder R, Stark DD, Elizondo G, et al (1988) MRI of hepatic lymphoma. Magn Reson Imaging 6:675–681

    Article  Google Scholar 

  • Wheeler DA, Edmondson HA (1985) Cystadenóma with mesenchvrnal stroma (CMS) in the liver and bile ducts. A clinicopathologic study of 17 cases, 4 with malignant change. Cancer 56:1434–1445

    Article  PubMed  CAS  Google Scholar 

  • Whelan JG, Creech JL, Tamburro CH (1976) Angiographic and radionuclide characteristics of hepatic angiosarcoma found in vinyl chloride workers. Radiology 118:549–557

    PubMed  Google Scholar 

  • White PG, Adams H, Smith PM (1993) The computed tomo-graphic appearances of angiosarcoma of the liver. Clin Radio! 48:321–325

    CAS  Google Scholar 

  • Ziegier JL, Beckstead JA, Volberding PA, et al (1984) Non-Hodgkin’s lymphoma in 90 homosexual men: relation to generalized adenopathy and the acquired immunodeficiency syndrome. N Engl J Med 311:565–570

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, A. Gemelli University Hospital, Largo A. Gemelli 8, I-00168, Rome, Italy

    R. Manfredi MD, G. Maresca MD (Professor), A. R. Cotroneo MD (Professor), A. M. De Gaerano MD & P. Marano MD (Professor and Chairman)

Authors
  1. R. Manfredi MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Maresca MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. R. Cotroneo MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. M. De Gaerano MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. P. Marano MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Diagnostic and Interventional Radiology, Department of Oncology, University of Pisa, Via Roma 67, I-56125, Pisa, Italy

    C. Bartolozzi MD (Professor and Chairman) & R. Lencioni MD (Professor and Chairman) & 

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Manfredi, R., Maresca, G., Cotroneo, A.R., De Gaerano, A.M., Marano, P. (1999). Rare Primary Malignancies of the Liver. In: Bartolozzi, C., Lencioni, R. (eds) Liver Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58641-5_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-58641-5_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63679-0

  • Online ISBN: 978-3-642-58641-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation