Abstract
Worldwide, oral and pharyngeal squamous cell carcinoma account for an estimated incidence of about 575 000 tumors and 366 000 tumor deaths every year and, therefore, represent the majority of all head and neck neoplasms [55]. Regarding the entirety of tumor death in the United States, the proportion of oral and pharyngeal cancer approximates 3.8% for males and 1.3% for females, while in the western parts of Germany rates are 6.7% for males and 1.1% for females [13, 47]. The cancer registry of the “DÖSAK” (Deutsch Österreichisch Schweizerischer Arbeitskreis für Tumoren im Kiefer-Gesichtsbereich) recognized an average-relative 5-year survival rate of 49% on the basis of about 10000 documented cases [16]. For decades, smoking and alcohol abuse have been identified as substantial risk factors [8, 14, 5656], approximately two-thirds of oropharyngeal cancer manifestations are related to smoking in the western world. By contrast, in India and Sri Lanka this kind of cancer reaches a proportion of about 40% of all neoplasm and is associated with the long-term consumption of betel. In these countries, the majority of oral cancer patients are females [37].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Aassar SO, Fischbein NJ, Caputo GR, Kaplan MJ, Price DC, Singer MI, Dillon WP, Hawkins RA (1999) Metastatic head and neck cancer: role and usefulness of FDG-PET in locating occult primary tumors. Radiology 210:177–181
Anzai Y, Carroll WR, Quint DJ, Bradford CR, Minoshima S, Wolf GT, Wahl RL (1996) Recurrence of head and neck cancer after surgery or irradiation: prospective comparison of 2-deoxy-2-[F-18]-fluoro-D-glucose PET and MR imaging diagnoses. Radiology 200:135–141
Becker N, Wahrendorf J (eds) (1997) Atlas of Cancer Mortality in the Federal Republic of Germany. 3. edn. Springer, Berlin Heidelberg New York, p 70
Bier J (1982) Definitionen zum radikalchirurgischen Vorgehen bei Plattenepithelkarzinomen der Mundhöhle. Dtsch Z Mund Kiefer GesichtsChir 6:369–372
Braams JW, Pruim J, Freling NJN, Nikkels PGJ, Roodenburg JLN, Boering G, Vaalburg W, Vermey A (1995) Detection of lymph node metastases of squamous-cell cancer of the head and neck with FDG-PET and MRI. J Nucl Med 36:211–216
Braams JW, Pruim J, Kohle AC, Nikkels PGJ, Vaalburg W, Vermey A, Roodenburg JLN (1997) Detection of unknown primary head and neck tumors by positron emission tomography. Int J Oral Maxillofac Surg 26:112–115
Brennan CT, Sessions DG, Spitznagel EL, Harvey JE (1991) Surgical pathology of cancer of the oral cavity and oropharynx. Laryngoscope 101:1175–1197
Brugere J, Guenel P, Leclerc A, Rodriguez J (1985) Differential effects of tobacco and alcohol in cancer of the larynx, pharynx and mouth. Cancer 57:391–395
Byers RM, Weber RS, Andrews T, McGill D, Kare R, Wolf P (1997) Frequency and therapeutic implications of “skip metastases” in the neck from squamous carcinoma of the oral tongue. Head Neck 19:14–19
Clayman GL, Frank DF (1998) Selective neck dissection of anatomically appropriate levels is as efficacious as modified radical neck dissection for elective treatment of the clinically negative neck in patients with squamous cell carcinoma of the upper respiratory and digestive tracts. Arch Otolaryngol Head Neck Surg 124:348–352
Engelbrecht V, Pisar E, Fürst G, Mödder U (1995) Verlaufskontrolle and Rezidivdiagnostik maligner Kopf-and Halstumoren nach Radiochemotherapie. Fortschr Röntgenstr 162:304–310
Fakih AR, Rao RS, Borges AM, Patel AR (1989) Elective versus therapeutic neck dissection in early carcinoma of the oral tongue. Am J Surg 158:309–313
Fischbein NJ, Aassar OS, Caputo GR, Kaplan MJ, Singer MI, Price DC, Dillon WP, Hawkins RA (1998) Clinical utility of positron emission tomography with ’8F-fluordeoxyglucose in detecting residual/recurrent squamous cell carcinoma of the head and neck. Am J Neuroradiol 19:1187–1196
Graham S, Daygal H, Rohrer T, Swanson M, Sultz H, Shedd D, Fischman S (1977) Dentition, diet, tobacco and alcohol in the epidemiology of oral cancer. J Natl Cancer Inst 59:1611–1616
Giacomarra V, Tirelli G, Papanikolla L, Bussani R (1999) Predictive factors of nodal metastases in oral cavity and oropharynx carcinomas. Laryngoscope 109:795–799
Hassek S, Reicherts M, Kainz M, Howaldt H-P (1999) Zentralregister des DeutschÖsterreichisch-Schweizerischen Arbeitskreises für Tumoren im Kiefer-and Gesichtsbereich (DÖSAK): 9. Projektbericht
Hathaway PB, Mankoff DA, Maravilla KR, Austin Seymour MM, Ellis GK, Gralow JR, Cortese AA, Hayes CE, Moe RE (1999) Value of combined FDG PET and MR imaging in the evaluation of suspected recurrent local-regional breast cancer: preliminary experience. Radiology 210:807–814
Howaldt HP, Kainz M, Vorast H, Cappel I (1998) Prognostische Überlegungen zum Mundhöhlenkarzinom auf der Grundlage des DÖSAK-Tumorregisters. In: Esser E (ed) Disputation anläßlich des 48. Kongresses der Deutschen Gesellschaft für Mund-, Kiefer-and Gesichtschirurgie 03.06. 1998, Osnabrück, S 9–61
Hoh CK, Glaspy J, Rosen PF, Dahlbom M, Lee SJ, Kunkel L, Hawkin RA, Maddhi J, Phelps ME (1997) Whole-body FDG-PET imaging for staging of Hodgkin’s disease and lymphoma. J Nucl Med 38:343–348
Ichiya Y, Kuwabara Y, Otsuka M, Tahara T, Yoshikai T, Fukumura T, Jingu K, Masuda K (1991) Assessment of treatment response to cancer therapy using fluorine-l8-fluorodeoxyglucose and positron emission tomography. J Nucl Med 32:1655–1660
Jerusalem G, Beguin Y, Fasotte MF, Najjar F, Rigo P, Fillet G (1999) Whole-body positron emission tomography using ’$F-fluordeoxyglucose for posttreatment evaluation in Hodgkin’s disease and non-Hodgkin’s lymphoma has higher diagnostic and prognostic value than classical computed tomography scan imaging. Blood 94:429–433
Johnson JT (1998) Selective neck dissection in patients with squamous cell carcinoma of the upper respiratory and digestive tracts (comment). Arch Otolaryngol Head Neck Surg 124:353
Jones AS, Morar P, Philips DE, Field JK, Husband D, Helliwell TR (1995) Second primary tumors in patients with head and neck squamous cell carcinoma. Cancer 75:1343–1353
Kainz M, Howaldt HP (1997) 8. Projektbericht des Zentralen Tumorregisters des DÖSAK. Klinikum der Justus-Liebig Universität, Gießen
Keyes JW, Watson NE, Williams DW, Greven KM, McGuirth WF (1997) FDG-PET in head and neck cancer. Am J Radiol 169:1663–1669
Kotwall C, Sako K, Razack MS, Rao U, Bakamjian V, Shedd DP (1987) Metastatic patterns in squamous cell cancer of the head and neck. Am J Surg 154:439–442
Lapela M, Grénman R, Kurki T, Joensuu H, Leskinen S, Lindholm P, Haaparanta M, Ruotsalainen U, Minn H (1995) Head and neck cancer: detection of recurrence with PET and 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology 197:205–211
Laubenbacher C, Saumweber D, Wagner-Manslau C, Kau RJ, Herz M, Avril N, Ziegler S, Kruschke C, Arnold W, Schwaiger M (1995) Comparison of fluorine-18-fluorodeoxyglucose, PET, MRI and endoscopy for staging head and neck squamous cell carcinomas. J Nucl Med 26:1747–1757
Loré JM, Diaz-Ordaz E, Spaulding M, Chary K, Kaufman S, Lawrence W, Hong F, Gerold T, Sundquist N, Barrali RA (1995) Improved survival with preoperative chemotherapy followed by resection uncompromised by tumor response for advanced squamous cell carcinoma of the head and neck. Am J Surg 170:506–511
Mancuso AA, Drane WE, Mukherji SK (1994) The promise FDG in diagnosis and surveillance of head and neck cancer. Cancer 74:1193–1195
Mc Guirth WF, Williams DW, Keyes JW, Greven KM, Watson NE, Geisinger KR, Capellari JO (1995) A comparative diagnostic study of head and neck nodal netastases using positron emission tomography. Laryngoscope 105:373–375
McGuirth WF, Greven K, Williams D, Keyes JW, Watson N, Capellari JO, Geisinger KR (1998) PET scanning in head and neck oncology: a review. Head and Neck 20:208–215
Minn H, Paul R, Ahonen A (1988) Evaluation of treatment response to radiotherapy in head and neck cancer with fluorine-18 fluorodeoxyglucose. J Nucl Med 29:1521–1525
Minn H, Lapela M, Klemi PJ, Grénman R, Leskinen S, Lindholm P, Bergman J (1997) Prediction of survival with fluorine-18-fluorodeoxyglucose and PET in head and neck cancer. J Nucl Med 38:1907–1911
Mohr C, Bohndorf W, Gremmel H, Härle F, Hausamen JE, Hirche H, Molls M, Renner KH, Reuther J, Sach H, Schettler D, Scheunemann H, Thelen M (1992) Präoperative Radio-Chemotherapie und radikale Operation fortgeschrittener Mundhöhlenkarzinome - Abschlußergebnisse einer prospektiven Therapiestudie des DÖSAK. Fortschr Kiefer Gesichtschir 37:13–17
Mohr C (1998) Der heutige Stellenwert adjuvanter Verfahren im Behandlungskonzept des Plattenepithelkarzinoms der Mundhöhle und/oder des Oropharynx. In: Esser E (ed) Disputation anläßlich des 48. Kongresses der Deutschen Gesellschaft für Mund-, Kiefer-und Gesichtschirurgie 03. 06. 1998, Osnabrück, S 106–134
Nandakumar A, Thimmasetty KT, Sreeramareddy NM, Venugopal Rajanna TC, Vinutha Srivinas AT, Bhargava MK (1990) A population-based case-control investigation on cancers of the oral cavity in Bangalore, India. Br J Cancer 62:847–851
Rege S, Maass A, Chaiken L, Hoh CK, Choi Y, Lufkin R, Anzai Y, Juillard G, Maddahi J, Phelps ME (1994) Use of positron emission tomography with fluordeoxyglucose in patients with extracranial head and neck cancers. Cancer 73:3047–3058
Reich RH, Wegener G, Hausamen JE, Knobbe H (1990) 10-Jahres Studie zum Überleben nach ablativer Chirurgie von nicht vorbehandelten Mundhöhlenkarzinomen. Fortschr Kiefer Gesichtschir 37:30–33
Reske SN (1997) Konsensus-Onko-PET. Nuklearmedizin 36:45–46
Reisser Ch, Haberkorn U, Dimitrakopoulou-Strauss A, Seifert E, Strauss LG (1995) Chemotherapeutic management of head and neck malignancies with positron emission tomography. Arch Otolaryngol Head and Neck Surg 121:272–276
Remmler D, Byers R, Scheetz J, Shell B, White G, Zimmermann S, Goepfert H (1986) A prospective study of shoulder disability resulting from radical and modified neck dissections. Head Neck Surg 8:280–286
Sakamoto H, Nakai Y, Ohashi Y, Okamura T (1997) Positron emission tomographic imaging in head and neck lesions. Eur Arch Otorhinolaryngol 254:123–126
Schuller DE, Grecula JC, Gabauer RA, Bauer C, Au JLS, Smith RE, Haller JR, Mountain RE, Young DC, Nag S (1997) Intensified regimen for advanced head and neck squamous cell carcinomas. Arch Otolaryngol Head Neck Surg 123:139–144
Shah JP, Candela FC, Poddar AK (1990) The patterns of cervical lymph node metastases from squamous carcinoma of the oral cavity. Cancer 66:109–113
Shone GR, Yardley MP (1991) An audit into the incidence of handicap after unilateral radical neck dissection. J Laryngol Otol 105:760–762
Statistisches Bundesamt, Wiesbaden (1997) Gesundheitswesen: Reihe 4, Todesursachen in Deutschland 1996. Metzler Poeschel, Stuttgart
Strauss LG, Conti PS (1991) The application of PET in clinical oncology. J Nucl Med 32:623–648
Sun LM, Leung SW, Su CY, Wang CJ (1997) The relapse patterns and outcome of postoperative recurrent tongue cancer. J Oral Maxillofac Surg 55:827–831
Umeda M, Nishimatsu N, Teranobu O, Shimada K (1998) Criteria for diagnosing lymph node metastasis from squamous cell carcinoma on the oral cavity: a study of the relationship between computed tomographic and histologic findings and outcome. J Oral Maxillofac Surg 65:585–593
Van den Brekel MWM, Stel HV, Castelijns JA, Nauta JJP, van der Waal I, Valk J, Meyer CJLM, Snow GB (1990) Cervical lymph node metastasis: assessment of radiologie criteria. Radiology 177:379–384
Van den Brekel MWM, Castelijns JA, Reitsma LC, van der Waal I, Snow GB (1999) Outcome of observing the NO neck using ultrasonographic-guided cytology for follow up. Arch Otolaryngol Head Neck Surg 125:153–156
Wanebo HJ, Glicksman AS, Landman Ch, Slotman G, Doolittle Ch, Clak J, Koness RJ (1995) Preoperative cisplatin and accelerated hyperfractionated radiation induces high tumor response and control rates in patients with advanced head and neck cancer. Am J Surg 170:512–516
Wangerin K, Schow J (1992) Multiple primäre maligne Tumoren in Kiefer-Gesichtsbereich und oberem Aerodigestivtrakt. Fortschr Kiefer Gesichtschir 37:65–68
World Cancer Research Fund/American Institute for Cancer Research (1997) Food, nutrition and the prevention of cancer: a global perspective. BANTA Book Group, Menasha
Wynder EL, Bross IJ, Feldman RM (1957) A study of the etiological factors in cancer of the mouth. Cancer 10:1300–1323
Yii NW, Patel SG, Rhys-Evans PH, Breach NM (1999) Management of the NO neck in early cancer of the tongue. Clin Otolaryngol 24:75–79
Zupi A, Califano L, Mangone GM, Longo F, Piombiono P (1998) Surgical management of the neck in squamous carcinoma of the floor of the mouth. Oral Oncol 34:472–475
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kunkel, M. (2000). The role of FDG-PET in the management of oral squamous cell carcinoma (ICD-O-DA M-8070/3). In: Wieler, H.J., Coleman, R.E. (eds) PET in Clinical Oncology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57703-1_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-57703-1_12
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-642-63329-4
Online ISBN: 978-3-642-57703-1
eBook Packages: Springer Book Archive