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Morbus Parkinson — Gehirnerkrankung oder Ganzkörpererkrankung?

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Morbus Parkinson

Zusammenfassung

Mit dem idiopathischen Parkinson-Syndrom wird neurologischer- und psychiatrischerseits bevorzugt eine Störung der zentralen Motorik assoziiert, die sich in den Kardinalsymptomen Ruhetremor, Bradykinese, rigorartige Tonuserhöhung und zum Teil posturale Instabilität äußert. Aus psychiatrischer Sicht sind darüber hinaus Komplikationen in ca. 10 bis 20% zu erwaähnen.

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Literatur

  1. Aminoff MJ, Wilcox CS (1971) Assessment of autonomic function in patients with a Pakinsonian syndrome. Br Med J 4: 80–84

    Article  PubMed  CAS  Google Scholar 

  2. Appenzeller O, Goss JE (1971) Autonomic deficits in Parkinson’s syndrome. Arch Neurol 24: 50–57

    Article  PubMed  CAS  Google Scholar 

  3. Bannister R, Oppenheimer DR (1972) Degeberative diseases of the nervous system associated with autonomic failure. Brain 95: 457–474

    Article  PubMed  CAS  Google Scholar 

  4. Benecke R, Striimper P, Weiss H (1993) Electron transfer complexes I and IV of platelets are abnormal in Parkinson’s disease but normal in Parkinson-plus syndromes. Brain 116: 1451–1463

    Article  PubMed  Google Scholar 

  5. Bethlem J, Den Hartog Jager WA (1960) Zje incidence and characteristics of Lewy bodies on idiopathic paralysis agitans (Parkinson’s disease). J Neurol. Neurosurg Psychiatry 23: 74–80

    Article  PubMed  CAS  Google Scholar 

  6. Beyer MK, Herlofson K, Arsland D, Larsen JP (2001) Causes of death in a community-based study of Parkinson’s disease. Acta Neurol Scand 103: 7–11

    Article  PubMed  CAS  Google Scholar 

  7. Braune S, Reinhardt M, Schnitzer R, Riedel A, Lücking CH (1999) Cardiac uptake of [123I]MIBG separates Parkinson’s disease from multiple system atrophy. Neurology 53: 1020–1025

    Article  PubMed  CAS  Google Scholar 

  8. Eady MJ (1963) Gastric secretion in parkinsonism. Australas Ann Med 12: 346–350

    Google Scholar 

  9. Eady MJ, Tyrer JH (1965) Alimentary disorder on parkinsonism. Australas Ann Med 14: 13–22

    Google Scholar 

  10. Edwards L, Quigley EMM, Hofman R, Pfeiffer TF (1993) Gastrointestinal symptoms in Parkinson Disease: 18-month follow-up study. Mov Disord 8: 83–86

    Article  PubMed  CAS  Google Scholar 

  11. Elliot K, Côté LJ, Frewin DB, Downey JA (1974) Vascular responses in the hands of Parkinson’s disease patients. Neurology 24: 857–862

    Article  Google Scholar 

  12. Forno LS (1986) The Lewy body in Parkinson’s disease. Adv Neurol 45: 95–43

    Google Scholar 

  13. Goetz CG, Lutge W, Tanner CM (1986) Autonomic dysfunction in Parkinson’s disease. Neurology 36: 73–75

    Article  PubMed  CAS  Google Scholar 

  14. Greenfield JG, Bosanquet FD (1953) The brain-stem lesions in parkinsonism. J Neurol Neurosurg Psychiatry 16: 213–226

    Article  PubMed  CAS  Google Scholar 

  15. Gu M, Cooper JM, Taanman JM, Schapira AHV (1998) Mitochondrial DNA transmission of the mitochondrial defect in Parkinson’s disease. Ann Neurol 44: 177–186

    Article  PubMed  CAS  Google Scholar 

  16. Hess CW, Enderli JB, Frohlich-Egli F, Ludin HP (1987) Neurogene Blasenfunktiönsstorungen beim Morbus Parkinson. Nervenarzt 58: 55–60

    PubMed  CAS  Google Scholar 

  17. Hoehn MM, Yahr MD (1967) Parkinsonism. Onset, progression and mortality. Neurology 17: 427–442

    Article  PubMed  CAS  Google Scholar 

  18. Indo T, Ando K (1982) Metclopramide-induced parkinsonism. Arch Neurol 39: 494–496

    Article  PubMed  CAS  Google Scholar 

  19. Janetzky B, Hauck S, Youdim MB, Riederer P, Jellinger K, Pantucek F, Zochling R, Boissl KW, Reichmann H (1994) Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson’s disease. Neurosci Lett 169: 126–128

    Article  PubMed  CAS  Google Scholar 

  20. Javoy-Agid F, Ruberg M, Pique L, Berzagna X et al. (1984) Biochemistry of the hypothalamus in Parkinson’s disease. Neurology 34: 672–675

    Article  PubMed  CAS  Google Scholar 

  21. Jost WH (1999) Autonome Regulationsstorungen beim Parkinson-Syndrom. Shaker, Aachen

    Google Scholar 

  22. Korczyn AD (1990) Autonomic nervous system disturbances in Parkinson’s disease. Adv Neurol 53: 463–468

    PubMed  CAS  Google Scholar 

  23. Kuroiwa Y, Shimada Y, Toyokura Y (1983) Postural hypotension and low RR-interval variability in parkinsonism, spinocerebellar degeneration, and Shy-Drager syndrome. Neurology 33: 463–467

    Article  PubMed  CAS  Google Scholar 

  24. Kuroiwa Y, Wada T, Tohgi H (1987) Measurement of blood pressure and heart-rate variation while resting supine and standing for the evaluation of autonomic dysfunction. J Neurol 235: 65–68

    Article  PubMed  CAS  Google Scholar 

  25. Laroche M, Delisle MB, Aziza R, Lagarrigue J, Mazieres B (1995) Is camptocormia a primary muscular disease? Spine 20: 1011–1016

    Article  PubMed  CAS  Google Scholar 

  26. Lees AJ, for the PDRG-UK (1995) Comparison of the therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson’s disease. Brit Med J 311: 1602–1607

    Article  PubMed  CAS  Google Scholar 

  27. Lewy FH (1913) Zur pathologischen Anatomie der Paralysis agitans. Dtsch Z Nervenheik 50: 50–55

    Google Scholar 

  28. Malarkey WB, Cyrus J, Paulson GW (1974) Dissociation of growth hormone and prolactin secretion in Parkinson’s disease following chronic L-Dopa therapy. J Clin Endocrin Metab 39: 229–235

    Article  CAS  Google Scholar 

  29. Mano Y, Nakamuro T, Takayanagi T, Mayer RF (1994) Sweat function in Parkinson’s disease. J Neurol 241: 573–576

    Article  PubMed  CAS  Google Scholar 

  30. Martignoni E, Pacchetti C, Godi L, Micieli G, Nappi G (1995) Autonomic disorders in Parkinson’s syndrome. J Neural Transm 45 Suppl: 11–19

    CAS  Google Scholar 

  31. Meco H, Pratesi L, Bonifati V (1991) Cardiovascular reflexes and autonomic dysfunction in Parkinson’s disease. J Neurol 238: 195–199

    Article  PubMed  CAS  Google Scholar 

  32. Mesec A, Sega S, Kiauta T (1993) The influence of type, duration, severity and levodopa treatment of Parkinson’s disease on cardiovascular autonomic responses. Clin Autonom Res 3: 339–344

    Article  CAS  Google Scholar 

  33. Mosewich RK, Rajput AH, Shuaib A, Rozdilsky B, Ang L (1994) Pulmonary embolism: an under-recognized yet frequent cause of death in parkinsonism. Mov Disord 9: 350–352

    Article  PubMed  CAS  Google Scholar 

  34. Parkinson J (1817) An essay in the shaking palsy. Sherwood, Neely, and Jones, London

    Google Scholar 

  35. Piha SJ, Rinne JO, Rinne UK, Seppänen A (1988) Autonomic dysfunction in recent onset and advanced Parkinson’s disease. Clin Neurol Neurosurg 90: 221–226

    Article  PubMed  CAS  Google Scholar 

  36. Przuntek H, Welzel D, Gerlach M, Bliimner E, Danielczyk W, Kaiser HJ, Kraus PH, Letzel H, Riederer P, Überla K (1996) Early institution of bromocriptine in Parkinson’s disease inhibits the emergence of levodopa associated motor side effects. Long-term results of the PRADO study. J Neural Transm 103: 699–715

    Article  PubMed  CAS  Google Scholar 

  37. Rajput AH, Rozdilsky B (1976) Dysautonomia in parkinsonism: a clinicopathological study. J Neurol Neurosurg Psychiatry 39: 1092–1100

    Article  PubMed  CAS  Google Scholar 

  38. Reichmann H, Janetzky B, Bischof F, Seibel P, Schöls L, Kuhn W, Przuntek H (1994) Unaltered respiratory chain enzyme activity and mitochondrial DNA in skeletal muscle from patients with idiopathic Parkinson’s syndrome. Eur Neurol 34: 263–267

    Article  PubMed  CAS  Google Scholar 

  39. Sabate M, Gonzalez I, Ruperez F, Rodriguez M (1996) Obstructive and restricitive pulmonary dysfunctions in Parkinson’s disease. J Neurol Sci 138: 114–119

    Article  PubMed  CAS  Google Scholar 

  40. Sato Y, Kaji M, Tsuru T, Oizumi K (2001) Risk factors for hip fracture among elderly patients with Parkinson’s disease. J Neurol Sci 182: 89–93

    Article  PubMed  CAS  Google Scholar 

  41. Shoffner JM, Watts RI, Juncos JL, Torroni A, Wallace DC (1991) Mitochondrial oxidative phosphorylation defects in Parkinson’s disease. Ann Neurol 30: 332–339

    Article  PubMed  CAS  Google Scholar 

  42. Taly AB, Muthane UB (1992) Involvement of peripheral nervous system in juvenile Parkinson’s disease. Acta Neurol Scand 85: 272–275

    Article  PubMed  CAS  Google Scholar 

  43. Wakabayashi K, Takahashi S (1997) Neuropathology of the autonomic nervous system in Parkinson’s disease. Eur Neurol 38 Suppl 2: 2–7

    Article  Google Scholar 

  44. Wakabayashi K, Takahashi S, Ohama E, Takeda S, Ikuta F (1993) Lewy bodies in the visceral nervous system in Parkinson’s disease. Adv Neurol 60: 609–612

    PubMed  CAS  Google Scholar 

  45. Watkins P (2000) COMT inhibitors and liver toxicity. Neurology 55: S51–52

    Article  PubMed  CAS  Google Scholar 

  46. Wermuth L, Stenager E (1995) Sexual problems in young patients with Parkinson’s disease. Acta Neurol Scand 91: 453–455

    Article  PubMed  CAS  Google Scholar 

  47. Winkler AS, Marsden J, Parton M, Watkins PJ, Chauduri KR (2001) Erythropoietin deficiency and anaemia in multiple system atrophy. Mov Disord 16: 233–239

    Article  PubMed  CAS  Google Scholar 

  48. Yoshita M (2000) Cardiac uptake of [123I]MIBG separates PD from multiple system atrophy. Neurology 54: 1977

    Article  Google Scholar 

  49. Ziemssen T, Süß M, Reichmann (2001) Funktionsdiagnostik des autonomen Nervensystems - eine interdisziplinäre Herausforderung. Sächsisches Ärzteblatt 8: 363–379

    Google Scholar 

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Authors
  1. H. Reichmann
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  2. T. Ziemssen
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Editors and Affiliations

  1. Neurologische Klinik der Ruhr-Universität Bochum St. Josef-Hospital, Gudrunstraße 56, 44791, Bochum, Germany

    Horst Przuntek  & Thomas Müller  & 

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© 2003 Springer-Verlag Berlin Heidelberg

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Reichmann, H., Ziemssen, T. (2003). Morbus Parkinson — Gehirnerkrankung oder Ganzkörpererkrankung?. In: Przuntek, H., Müller, T. (eds) Morbus Parkinson. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57362-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-57362-0_4

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-7985-1422-5

  • Online ISBN: 978-3-642-57362-0

  • eBook Packages: Springer Book Archive

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