Abstract
Theoretical population genetics is surely a most unusual subject. At times it appears to have little connection with the parent subject on which it must depend, namely observational and experimental genetics, living an almost inbred life of its own. It cannot claim a status analogous to that of theoretical physics to justify doing this: the latter subject depends on very precise observational data and very precise models, so that if at times it proceeds ahead of observational physics on its own, it is on the basis of quite firm foundations. Theoretical population genetics, on the other hand, rests on often vague and sometimes contradictory foundations and too inbred a development of the theory soon leads to irrelevancy. What should be the methods of progress in population genetics theory, and how should these methods change with changes in mainstream genetics?
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References
Dawkins, R. (1986). The Blind Watchmaker. Longman, Harlow.
Dobzhansky, T. (1970). Genetics of the Evolutionary Process. Columbia University Press, New York.
Ewens, W.J. (1989). An interpretation and proof of the fundamental theorem of natural selection. Theoret. Pop. Biol., 36, 167–180.
Ewens, W.J. (1993). Beanbag genetics and after, pp 7–29 in “Human Population Genetics: A Centennial Tribute to J.B.S. Haldane,” edited by Partha P. Majumder. Plenum Press, New York.
Feldman, M.W. (1972). Selection for linkage modification. 1. Random mating populations. Theoret. Pop. Biol., 3, 324–346.
Fisher, R.A. (1922). On the dominance ratio. Proc. Roy. Soc. Edin., 42, 321–341.
Fisher, R.A. (1930). The Genetical Theory of Natural Selection. Clarendon Press, Oxford.
Fisher, R.A. (1941). Average excess and average effect of a gene substitution. Ann. Eugen., 11, 53–63.
Fisher, R.A. (1958). The Genetical Theory of Natural Selection. Dover, New York.
Haldane, J.B.S. (1964). A defense of beanbag genetics. Perspectives in Biology and Medicine, 7, 343–359.
Hoyle, F. and Wickramasinghe, N. C. (1981). Evolution from Space., Dent, London.
Kimura, M. (1955). Solution of a process of random genetic drift with a continuous model. Proc. Nat. Acad.. Sci., 41, 144–150.
Kimura, M. (1968). Evolutionary rates at the molecular level. Nature, 217, 624–626.
Kimura, M. and Ohta, T. A. (1971). On the rate of molecular evolution. J. Mol. Biol. 1, 1–17.
Kingman, J. F. C. (1961). A mathematical problem in population genetics. Proc. Camb. Phil. Soc, 57, 574–582.
Kingman, J. F.C. (1988). Typical polymorphisms maintained by natural selection. J. Appl. Prob., 25A, 113–125.
Lovetrup, S. (1987). Darwinism: the Refutation of a Myth. Croon Helm, London.
Mayr, E. (1963). Animal Species and Evolution. Harvard University Press, Cambridge MA.
Nei, M. (1967). Modification of linkage intensity by natural selection. Genetics, 57, 625–641.
Norton, H.T.J. (1915). Appendix to Mimicry in Butterflies, by R.C. Punnett. Cambridge University Press, Cambridge.
Price, G.R. (1972). Fisher Fundamental Theorem made clear. Ann. Hum. Genet., 36, 129–140.
Provine, W. (1986). Sewall Wright and Evolutionary Biology. University of Chicago Press, Chicago.
Schoemaker, P.J.H. (1991). The quest for optimality: a positive heuristic of science? Behav. and Brain Sci., 14, 205–245.
Simpson, G.G. (1944). Tempo and Mode in Evolution. Columbia University Press, New York.
Wright, S. (1930). The genetical theory of natural selection — a review. J. Hered., 21, 349–356.
Wright, S. (1931). Evolution in Mendelian populations. Genetics, 16, 97–159.
Wright, S. (1978). Evolution and the Genetics of Populations. Vol. 4. Variability within and among natural populations. University of Chicago Press, Chicago.
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© 1994 Springer-Verlag Berlin Heidelberg
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Ewens, W.J. (1994). The Changing Role of Population Genetics Theory. In: Levin, S.A. (eds) Frontiers in Mathematical Biology. Lecture Notes in Biomathematics, vol 100. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-50124-1_11
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