Abstract
Twenty years ago, ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS) were rarely diagnosed conditions, poorly understood and usually treated by mastectomy like all other breast cancers. During the intervening years important changes have occurred with regard to both invasive and non-invasive breast cancer. In particular, several trials have demonstrated the safety of breast conservation therapy for selected patients with unifocal invasive breast cancers measuring up to 4 cm diameter (Veronesi et al. 1995; Fisher et al. 1989; Van Dongen et al. 1992; Jacobson et al. 1995; Blichert-Toft et al. 1988). The paradox then became apparent that women with invasive cancers were being treated by breast conservation therapy yet those with the non-life-threatening DCIS were still being subjected to mastectomy.
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© 1998 Springer-Verlag Berlin · Heidelberg
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Fentiman, I.S. (1998). Trials of Treatment for Non-invasive Breast Cancer. In: Senn, HJ., Gelber, R.D., Goldhirsch, A., Thürlimann, B. (eds) Adjuvant Therapy of Primary Breast Cancer VI. Recent Results in Cancer Research, vol 152. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45769-2_12
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DOI: https://doi.org/10.1007/978-3-642-45769-2_12
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