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Diet and Mammary Gland Carcinogenesis

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Adjuvant Therapy of Primary Breast Cancer VI

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 152))

Abstract

The etiology of human breast cancer is largely unknown. However, there are three broad determinants of breast cancer risk. One determinant is heredity, such as carrying a germline mutation in the BRCA1 or BRCA2 gene. Another is hormonal and reproductive factors. Women have a 180-fold higher risk of breast cancer than men, and among women, the age at menarche, age at menopause, age at first childbirth, and parity influence breast cancer risk. A third determinant is environment, which includes the country where a woman was born and raised, lifestyle habits, and diet. It appears likely that these three broad factors are not mutually exclusive but are interactive, thereby adding to the complexity in the etiology of breast cancer.

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Author information

Authors and Affiliations

  1. Laboratory of Experimental Carcinogenesis, National Cancer Institute, Building 37, Room 3C28, Bethesda, MD, 20892-4255, USA

    E. G. Snyderwine

Authors
  1. E. G. Snyderwine
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Editor information

Editors and Affiliations

  1. Zentrum für Tumordiagnostik und Prävention, Rorschacherstrasse 150, CH-9006, St. Gallen, Switzerland

    Hans-Jörg Senn

  2. Dana Farber Cancer Institute Biostatistics, 44 Binney Street, Boston, 02115, USA

    Richard D. Gelber Ph.D

  3. Ospedale Civico, CH-6900, Lugano, Switzerland

    Aron Goldhirsch

  4. Klinik C für Innere Medizin Abteilung für Onkologie und Hämatologie, Kantonsspital St. Gallen, CH-9007, St. Gallen, Switzerland

    Beat Thürlimann

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© 1998 Springer-Verlag Berlin · Heidelberg

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Snyderwine, E.G. (1998). Diet and Mammary Gland Carcinogenesis. In: Senn, HJ., Gelber, R.D., Goldhirsch, A., Thürlimann, B. (eds) Adjuvant Therapy of Primary Breast Cancer VI. Recent Results in Cancer Research, vol 152. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45769-2_1

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  • DOI: https://doi.org/10.1007/978-3-642-45769-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45771-5

  • Online ISBN: 978-3-642-45769-2

  • eBook Packages: Springer Book Archive

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