Abstract
When dentinal tubules first become exposed, patients note that those areas become more sensitive to tactile, evaporative, and osmotic stimuli. However, over time, especially with poor plaque control, those areas become progressively truly hypersensitive. There are a number of mechanisms responsible for hypersensitivity including localized pulpal inflammation, sprouting of pulpal nerves, and expression of “inflammatory” sodium channels. Often such hypersensitivity spontaneously disappears. These protective mechanisms will be reviewed. The problem arises for patients whose exposed dentin becomes hypersensitive and whose endogenous protective mechanism fails to correct the hypersensitivity.
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Acknowledgement
This work was supported, in part, by R01 DE015306 from the NIDCR to DHP (PI) and by the King Abdulazziz University School of Dentistry to Prof. Pashley as their Hi-Ci dental scholar.
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Pashley, D.H. (2014). “How Can Sensitive Dentin Become Hypersensitive?”. In: Taha, S., Clarkson, B. (eds) Clinician's Guide to the Diagnosis and Management of Tooth Sensitivity. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45164-5_2
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DOI: https://doi.org/10.1007/978-3-642-45164-5_2
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