Abstract
Most women who present at the breast clinics have benign breast conditions which range from non-specific breast pain to discrete lumps such as fibroadenomas. Benign breast lesions consist of heterogenous conditions which in the majority of women go undetected and are identified incidentally during screening mammography or in the surgical specimens for cancer. Although most women present with benign breast conditions than with cancer, there is more written about breast cancer than benign lesions because this is the most common malignant tumour in women. Nomenclature of benign breast lesions was confusing in the past with the use of terms such as aberrations of normal development and involution (ANDI), which is supposed to encompass both the pathogenesis and the degree of abnormality (Hughes et al. 1987). The terminology used in this book for benign breast disease is based on the classification by the College of American Pathologists (Hutter 1986; Fitzgibbons et al. 1998) which is used by the UK NHS Breast Screening Programme (2005).
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References
Ader DN, Shriver CD (1997) Cyclical mastalgia: prevalence and impact in an outpatient breast clinic sample. J Am Coll Surg 185:466–470
Carter CL, Cork DK, Micozzi MS et al (1988) A prospective study of the development of breast cancer in 16,692 women with benign breast disease. Am J Epidemiol 128:467–477
Chlebowski RT, Collyer DE, Somerfield MR et al (1999) American Society of Clinical Oncology technology assessment on breast cancer risk reduction strategies: tamoxifen and raloxifene. J Clin Oncol 17:1939–1955 (3)
Claus FB, Risch N, Thompson WD (1994) Autosomal dominant inheritance of early onset breast cancer: implication for risk prediction. Cancer 73:643–651
Duport WD, Page DL (1985) Risk factors for breast cancer in women with proliferative disease. N Engl J Med 312:146–151
Duport WD, Parl FF, Hartman WH et al (1993) Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer 71:1258–1265
Fitzgibbons PL, Henson DE, Hutter RVP (1998) Benign breast changes and the risk for subsequent breast cancer an update of the 1985 consensus statement: Cancer Committee of the College of American Pathologists. Arch Pathol Lab Med 122:1053–1055
Gail MH, Brinton LA, Byar DP et al (1989) Projecting individualised probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 81:1879–1886
Gail HM, Costantino JP, Bryant J et al (1999) Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer. J Natl Cancer Inst 91:1829–1946
Garcia-Tunon I, Ricate M, Ruiz A et al (2006) Role of tumor necrosis factor α and its receptors in human benign breast lesions and tumor (in-situ and infiltrative). Cancer Sci 97:1044–1049
Goehring C, Morabia A (1997) Epidemiology of benign breast disease, with special interest to histologic types. Epidem Rev 19:310–327
Guray M, Sahin AA (2006) Benign breast diseases: classification, diagnosis and management. Oncologist 11:435–449
Hartman LC, Sellers TA, Frost MH et al (2005) Benign breast disease and the risk of breast cancer. N Engl J Med 353:229–237
Huang Z, Hankinson SE, Colditz GA (1997) Dual effects of weight and weight gain on breast cancer risk. J Am Med Assoc 278:1407–1414
Hughes LE, Mansel RE, Webster DJTW (1987) Aberrations of normal development and involutions (ANDI): a new perspective on pathogenesis and nomenclature of benign breast disorders. Lancet 2:1316–1319
Hutter RVP (1986) Consensus meeting: is fibrocystic disease of the breast precancerous? Arch Pathol Lab Med 110:171–173
Mansel RE, Webster DTJ, Sweetland HM (eds) (2009) Nipple discharge In: Hughes, Mansel & Webster’s benign disorders and diseases of the breast, 3rd edn. China: Saunders Elsevier, pp 207–225
NHS BSP Publication No: 58 (2005) Pathology reporting of breast disease. A joint document incorporating the third edition of the NHS Breast Screening Programme’s guidelines for pathology reporting in breast cancer screening and the second edition of The Royal College of Pathologists’ minimum dataset for breast cancer histopathology
Santen RJ (2010) Benign breast disease in women. http://www.endotext.org/pregnancy5/pregnancy5.htm
Shetty MK, Shah YP, Sharman RS (2003) Prospective evaluation of the value of combined mammographic and sonographic assessment in patients with palpable abnormalities of the breast. J Ultrasound Med 22:263–268
Stark A, Hulka BS, Joens S et al (2000) Her-2/new amplification in benign breast disease and risk of subsequent breast cancer. J Clin Oncol 18:267–274
Tyrer J, Duffy SW, Cuzick J (2004) A breast cancer prediction model incorporating familial and personal risk factors. Stat Med 23:1111–1130
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Chinyama, C.N. (2014). Overview of Benign Breast Lesions. In: Benign Breast Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-41065-9_2
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DOI: https://doi.org/10.1007/978-3-642-41065-9_2
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