Abstract
Accurate assessment of glomerular filtration rate (GFR) is important as it has multiple clinical implications. However in older adults and in patients with non-stable renal function (as it occurs during acute kidney injury for example) this is difficult. Most currently used GFR estimating equations based on serum creatinine were not developed and validated in populations of older adults. Besides, serum creatinine is known to be an imprecise endogenous filtration marker as it is strongly influenced by muscle mass. Two new serum creatinine- and serum Cystatin C-based eGFR equations have been specifically developed for older adults, however more confirmation of these findings by external validation is needed.
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Schaeffner, E. (2014). Assessing Glomerular Filtration Rate in Older Adults. In: Haase, M., Haase-Fielitz, A. (eds) Managing Renal Injury in the Elderly Patient. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39947-3_3
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DOI: https://doi.org/10.1007/978-3-642-39947-3_3
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