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Effect of Tip Size on Gigaseal Formation

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Gigaseal Formation in Patch Clamping

Part of the book series: SpringerBriefs in Applied Sciences and Technology ((BRIEFSAPPLSCIENCES))

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Abstract

This chapter reports the research into the effect of tip size on gigaseal formation. The approach adopted in the research includes, first, investigation on how the tip size affects the patch clamping, then a study on the surface properties of pipettes with different tip sizes and compare the seal resistances obtained by them, and finally verification of the conclusions using experiments.

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Author information

Authors and Affiliations

  1. London Centre for Nanotechnology, Gordon Street 17-19, London, WC1H 0AH, UK

    Majid Malboubi

  2. School of Mechanical Engineering, The University of Birmingham, Birmingham, B15 2TT, UK

    Kyle Jiang

Authors
  1. Majid Malboubi
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  2. Kyle Jiang
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Correspondence to Majid Malboubi .

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Malboubi, M., Jiang, K. (2014). Effect of Tip Size on Gigaseal Formation. In: Gigaseal Formation in Patch Clamping. SpringerBriefs in Applied Sciences and Technology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39128-6_6

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  • DOI: https://doi.org/10.1007/978-3-642-39128-6_6

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39127-9

  • Online ISBN: 978-3-642-39128-6

  • eBook Packages: EngineeringEngineering (R0)

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