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Acute Tubular Necrosis

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Fundamentals of Renal Pathology

Abstract

Acute tubular necrosis (ATN) is a pathologic process that manifests clinically as acute renal failure. Although the term implies cellular death (necrosis), it should be appreciated that frank necrosis is not a constant finding; evidence of sublethal cellular injury is common. Thus, a more descriptive term “acute tubular injury” is in common use in many centers. Furthermore, there is often a lack of clinical-pathologic correlation, with severe acute kidney injury sometimes associated with trivial morphologic findings [1, 2]

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Fogo, A.B., Cohen, A.H., Colvin, R.B., Jennette, J.C., Alpers, C.E. (2014). Acute Tubular Necrosis. In: Fundamentals of Renal Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39080-7_15

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  • DOI: https://doi.org/10.1007/978-3-642-39080-7_15

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-39079-1

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