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Genitourinary Cytopathology (Kidney and Urinary Tract)

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Cytopathology in Oncology

Part of the book series: Cancer Treatment and Research ((CTAR,volume 160))

Abstract

This chapter focuses on genitourinary tract cytology, specifically fine needle aspiration (FNA) of the renal mass lesions and urinary tract cytology. FNAs of renal masses have been performed for diagnosis or confirmation of advanced neoplasia and metastases, and/or staging of tumors. In the age of multimodality treatment options (surgery, cryoablation, radiofrequency ablation, etc.), there is a role for precise pretreatment characterization of the renal masses by FNA, which would decrease the unnecessary treatment for benign diseases and reduce the treatment-related mortality and morbidity in addition to reducing the patient care costs. To date, urine cytology remains the gold standard for bladder cancer screening. It has been, and still is the test against which all new tests are compared when evaluating potential bladder tumor markers. In the last 20 years, a number of noninvasive tests have been developed to detect urothelial carcinoma. Although some have been able to show a better sensitivity compared to cytology, only a few have been close to reaching the sensitivity seen in cytology. Combining some of the new markers with cytologic evaluation may optimize their performance status.

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Authors and Affiliations

  1. Department of Pathology, Loyola University Medical Center, 2160 South First Ave, Maywood, IL, 60153, USA

    Güliz A. Barkan & Eva M. Wojcik

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  1. Güliz A. Barkan
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  2. Eva M. Wojcik
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Correspondence to Güliz A. Barkan .

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  1. Feinberg School of Medicine Northwestern University, Chicago, Illinois, USA

    Ritu Nayar

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Barkan, G.A., Wojcik, E.M. (2014). Genitourinary Cytopathology (Kidney and Urinary Tract). In: Nayar, R. (eds) Cytopathology in Oncology. Cancer Treatment and Research, vol 160. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38850-7_7

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  • DOI: https://doi.org/10.1007/978-3-642-38850-7_7

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