Abstract
Regulations of food intake and energy expenditure are important to maintain normal weight [1]. Ghrelin produced by the stomach modulates short-term appetitive control, and leptin is produced by adipose tissue to signal fat storage reserves in the body and mediates long-term appetitive controls. For several reasons, homeostasis of energy balance can be broken, of which underlying mechanisms are remain incompletely understood. When calorie intake exceeds energy expenditure, the extra energy is stored in various organs. The main characteristic of obesity is long-term imbalance between calorie intake and energy expenditure, resulting in over accumulation of fat in body.
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Choi, S.H. (2014). Physiology of Morbid Obese Patients. In: Choi, S., Kasama, K. (eds) Bariatric and Metabolic Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35591-2_1
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DOI: https://doi.org/10.1007/978-3-642-35591-2_1
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