Abstract
Mucinous breast lesions refer to a broad spectrum of entities, ranging from benign fibrocystic changes with luminal mucin to mucocele-like lesions and invasive mucinous carcinoma. There are also lesions with stromal mucinous or myxoid material that mimic the more conventional “mucinous” entities.
Mucins are complex carbohydrates secreted by specialized epithelial and occasionally by connective tissue cells. “Mucoid” and “myxoid” are traditionally used to refer to extracellular mucosubstances of epithelial and mesenchymal origins, respectively.
Apart from lesions associated with extracellular mucin, lobular neoplasia, ductal carcinoma in situ, and infiltrative lobular carcinomas can demonstrate intracytoplasmic mucin. Stromal myxoid changes can be observed in fibroadenomas and phyllodes tumors, as well as in the less common lesions of pleomorphic adenoma and nodular mucinosis
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Tse, G., Tan, P.H., Schmitt, F. (2013). Mucinous Lesions. In: Fine Needle Aspiration Cytology of the Breast. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35000-9_11
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DOI: https://doi.org/10.1007/978-3-642-35000-9_11
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