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Atomic Force Microscopy in Bioengineering Applications

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Scanning Probe Microscopy in Nanoscience and Nanotechnology 3

Part of the book series: NanoScience and Technology ((NANO))

Abstract

The high lateral resolution imaging and its technical versatility in property evaluation, together with the relatively straightforward characterization of viable biological structures in liquid media, render the AFM an unrivaled instrument in the definition of novel structural–functional relationships in bioengineering domains. This chapter provides an overview of the AFM-based techniques employed in the analysis of biological structures and biomaterials.A brief introduction to the working principles of the AFM is followed by a description of application developments. Relevant findings on the structural and functional characterization of biomaterials and biological structures at submicrometric scales are highlighted.

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Acknowledgements

The authors are grateful to B. Saramago and A. P. Serro and to all the Nanolab students (http://nanolab.ist.utl.pt) for the joint work and discussions over the years. The Portuguese Foundation for Science and Technology has supported much of the atomic force microscopy work carried out at the Nanolab (Eurocore FANAS/001-Nanoparma, PTDC/CTM/100163/2008 and PTDC/SAU-ENB/111941/2009 grants).

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    R. Colaço & P. A. Carvalho

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  1. , Nanoprobe Laboratory for Bio- &, Ohio State University, West 19th Avenue 201, Columbus, 43210-1142, Ohio, USA

    Bharat Bhushan

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Colaço, R., Carvalho, P.A. (2012). Atomic Force Microscopy in Bioengineering Applications. In: Bhushan, B. (eds) Scanning Probe Microscopy in Nanoscience and Nanotechnology 3. NanoScience and Technology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25414-7_15

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