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MicroRNA or Not MicroRNA?

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Advances in Bioinformatics and Computational Biology (BSB 2011)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 6832))

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Abstract

The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict with other ncRNAs, in particular snoRNAs. With few exceptions, these cases show little similarities to canonical microRNAs, however, and thus they should be considered as mis-annotations.

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Author information

Authors and Affiliations

  1. Bioinformatics Group, Department of Computer Science, UK

    David Langenberger, Sebastian Bartschat, Jana Hertel, Hakim Tafer & Peter F. Stadler

  2. Interdisciplinary Center for Bioinformatics, University of Leipzig, Härtelstraße 16-18, D-04107, Leipzig, Germany

    David Langenberger, Jana Hertel, Steve Hoffmann, Hakim Tafer & Peter F. Stadler

  3. LIFE – Leipzig Research Center for Civilization Diseases, University of Leipzig, Germany

    David Langenberger, Steve Hoffmann & Peter F. Stadler

  4. Max Planck Institute for Mathematics in the Sciences, Inselstraße 22, D-04103, Leipzig, Germany

    Peter F. Stadler

  5. Fraunhofer Institut für Zelltherapie und Immunologie, Perlickstraße 1, D-04103, Leipzig, Germany

    Peter F. Stadler

  6. Department of Theoretical Chemistry, University of Vienna, Währingerstraße 17, A-1090, Wien, Austria

    Peter F. Stadler

  7. Center for non-coding RNA in Technology and Health, University of Copenhagen, Grønnegårdsvej 3, DK-1870, Frederiksberg C, Denmark

    Peter F. Stadler

  8. Santa Fe Institute, 1399 Hyde Park Rd., Santa Fe, NM, 87501, USA

    Peter F. Stadler

Authors
  1. David Langenberger
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  2. Sebastian Bartschat
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  3. Jana Hertel
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  4. Steve Hoffmann
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  5. Hakim Tafer
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  6. Peter F. Stadler
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Editor information

Editors and Affiliations

  1. Faculdade de Informática - PUCRS, Avenida Ipiranga, 6681, Prédio 32 - Sala 608, 90619-900, Porto, Alegre-RS, Brazil

    Osmar Norberto de Souza

  2. Instituto de Computação - Unicamp, Avenida, Albert Einstein, 1251, 13083-852, Campinas-SP, Brazil

    Guilherme P. Telles

  3. Indiana University Purdue University Indianapolis, 535 W. Michigan Str. IT 477, 46202, Indianapolis, IN, USA

    Mathew Palakal

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Langenberger, D., Bartschat, S., Hertel, J., Hoffmann, S., Tafer, H., Stadler, P.F. (2011). MicroRNA or Not MicroRNA?. In: Norberto de Souza, O., Telles, G.P., Palakal, M. (eds) Advances in Bioinformatics and Computational Biology. BSB 2011. Lecture Notes in Computer Science(), vol 6832. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22825-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-22825-4_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-22824-7

  • Online ISBN: 978-3-642-22825-4

  • eBook Packages: Computer ScienceComputer Science (R0)

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