Skip to main content
SpringerLink
Log in

Functional Magnetic Resonance Imaging

  • Chapter
  • First Online:
Handbook of Computational Statistics

Part of the book series: Springer Handbooks of Computational Statistics ((SHCS))

  • 12k Accesses

Abstract

The 2003 Nobel Prize in Medicine went to Paul Lauterbur and Sir Peter Mansfield for the invention of magnetic resonance imaging (MRI) in the 1970s. Since its invention MRI has rapidly changed the world of medicine; there are currently more than 20,000 MRI scanners in the world and many millions of images are generated by them each year. In the early 1990s, Ogawa et al. (1992), Belliveau et al. (1991) and Kwong et al. (1992) showed that MRI could be used for the detection of brain function.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Belliveau, J.W., Kennedy, D.N., McKinstry, R.C., Buchbinder, B.R., Weisskoff, R.M., Cohen, M.S., Vevea, J.M., Brady, T.J., Rosen, B.R.: Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254, 716–719 (1991)

    Article  Google Scholar 

  • Biswal, B., DeYoe, E.A., Hyde, J.S.: Reduction of physiological fluctuations in fMRI using digital filters. Magn. Reson. Med. 35, 107–113 (1996)

    Article  Google Scholar 

  • Buxton, R.B.: Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques, Cambridge University Press, Cambridge (2002)

    Google Scholar 

  • Cherry, S.R., Phelps, M.E.: Imaging brain function with positron emission tomography. In: Toga, A.W., Mazziotta, J.C. (eds.) Brain Mapping: The Methods. Academic Press, New York (1996)

    Google Scholar 

  • Chuang, K.H., Chen, J.H.: IMPACT: Image-based physiological artifacts estimation and correction technique for functional MRI. Magn. Reson. Med. 46, 344–353 (2001)

    Article  Google Scholar 

  • Dagli, M.S., Ingeholm, J.E., Haxby, J.V.: Localization of cardiac-induced signal change in fMRI. NeuroImage 9, 407–415 (1999)

    Article  Google Scholar 

  • Eddy, W.F., Fitzgerald, M., Genovese, C.R., Mockus, A., Noll, D.C.: Functional imaging analysis software – computational olio. In: Prat, A. (eds.) Proceedings in Computational Statistics, Physica, Heidelberg (1996a)

    Google Scholar 

  • Eddy, W.F., Fitzgerald, M., Noll, D.C.: Improved image registration by using Fourier interpolation. Magn. Reson. Med. 36, 923–931 (1996b)

    Article  Google Scholar 

  • Eddy, W.F., Fitzgerald, M., Genovese, C., Lazar, N., Mockus, A., Welling, J.: The challenge of functional magnetic resonance imaging. J. Comp. Graph. Stat. 8(3), 545–558 (1999); Adapted from: The challenge of functional magnetic resonance imaging. In Massive Data Sets, Proceedings of a Workshop, pp. 39–45. National Academy Press, Washington, DC (1996)

    Google Scholar 

  • Eddy, W.F., Young, T.K.: Optimizing the resampling of registered images. In: Bankman, I.N. (eds.) Handbook of Medical Imaging: Processing and Analysis. Academic Press, New York (2000)

    Google Scholar 

  • Eden, G.F., Zeffiro, T.A.: PET and fMRI in the detection of task-related brain activity: Implications for the study of brain development. In: Thacher, R.W., Lyon, G.R., Rumsey, J., Krasnegor, N.K. (eds.) Developmental NeuroImaging: Mapping the Development of Brain and Behavior, Academic Press, San Diego (1997)

    Google Scholar 

  • Finger, S.: Origins of Neuroscience: A History of Explorations Into Brain Function, Oxford University Press, Oxford (1994)

    Google Scholar 

  • Forman, S.D., Cohen, J.D., Fitzgerald, M., Eddy, W.F., Mintun, M.A., Noll, D.C.: Improved assessment of significant change in functional magnetic resonance imaging (fMRI): Use of a cluster size threshold. Magn. Reson. Med. 33, 636–647 (1995)

    Article  Google Scholar 

  • Friston, K.J., Williams, S., Howard, R., Frackowiak, R.S.J., Turner, R.: Movement-related effects in fMRI time-series. Magn. Reson. Med. 35, 346–355 (1996)

    Article  Google Scholar 

  • Gaillard, W.D., Grandin, C.B., Xu, B.: Developmental aspects of pediatric fMRI: Considerations for image acquisition, analysis, and interpretation. NeuroImage 13, 239–249 (2001)

    Article  Google Scholar 

  • Genovese, C.R.: A Bayesian time-course model for functional magnetic resonance imaging (with discussion). J. Am. Stat. Assoc. 95, 691–703 (2000)

    Article  Google Scholar 

  • Genovese, C.R., Lazar, N.A., Nichols, T.E.: Thresholding of statistical maps in neuroimaging using the false discovery rate. NeuroImage 15, 870–878 (2002)

    Article  Google Scholar 

  • Glad, I., Sebastiani, G.: A Bayesian approach to synthetic magnetic resonance imaging. Biometrika 82, 237–250 (1995)

    Article  MathSciNet  MATH  Google Scholar 

  • Glover, G.H., Li, T.Q., Ress, D.: Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR. Magn. Reson. Med. 44, 162–167 (2000)

    Article  Google Scholar 

  • Green, M.V., Seidel, J., Stein, S.D., Tedder, T.E., Kempner, K.M., Kertzman, C., Zeffiro, T.A.: Head movement in normal subjects during simulated PET brain imaging with and without head restraint. J. Nucl. Med. 35(9), 1538–1546 (1994)

    Google Scholar 

  • Guimaraes, A.R., Melcher, J.R., Talavage, T.M., Baker, A.J., Rosen, B.R., Weisskoff, R.M.: Detection of inferior colliculus activity during auditory stimulation using cardiac-gated functional MRI with T 1 correction. In: NeuroImage, 2nd International Conference on Functional Mapping of the Human Brain (1996)

    Google Scholar 

  • Hajnal, J.V., Myers,R., Oatridge, A., Schwieso, J.E., Young, I.R., Bydder, G.M.: Artifacts due to stimulus correlated motion in functional imaging of the brain. Magn. Reson. Med. 31, 283–291 (1994)

    Article  Google Scholar 

  • Harrison, L., Penny, W.D., Friston, K.: Multivariate Autoregressive Modeling of fMRI time series. NeuroImage 19(4), 1477–1491 (2003)

    Article  Google Scholar 

  • Hu, X., Le, T.H., Parrish, R., Erhard, P.: Retrospective estimation and correction of physiological fluctuation in functional MRI. Magn. Reson. Med. 34, 201–212 (1995)

    Article  Google Scholar 

  • Jezzard, P.: Sources of distortion in functional MRI data. Hum. Brain Map. 8, 80–85 (1999)

    Article  Google Scholar 

  • Jezzard, P., Balaban, R.S.: Correction for geometric distortions in echo planar images from B 0 field variations. Magn. Reson. Med. 34, 65–73 (1995)

    Article  Google Scholar 

  • Kim, B., Boes, J.L., Bland, P.H., Chenevert, T.L., Meyer, C.R.: Motion correction in fMRI via registration of individual slices into an anatomical volume. Magn. Reson. Med. 41, 964–972 (1999)

    Article  Google Scholar 

  • Kwong, K.K., Belliveau, J.W., Chesler, D.A., Goldberg, I.E., Weisskoff, R.M., Poncelet, B.P., Kennedy, D.N., Hoppel, B.E., Cohen, M.S., Turner, R., Cheng, H., Brady, T.J., Rosen, B.R.: Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. USA 89, 5675 (1992)

    Article  Google Scholar 

  • Lange, N.: Statistical approaches to human brain mapping by functional magnetic resonance imaging. Stat. Med. 15, 389–428 (1996)

    Article  Google Scholar 

  • Lange, N., Zeger, S.L.: Non-linear Fourier time series analysis for human brain mapping by functional magnetic resonance imaging (with discussion). Appl. Stat. 46, 1–29 (1997)

    Article  MathSciNet  MATH  Google Scholar 

  • Lazar, N.A., Genovese, C.R., Eddy, W.F., Welling, J.: Statistical issues in fMRI for brain imaging. Int. Stat. Rev. 69, 105–127 (2001)

    Article  MATH  Google Scholar 

  • Lee, C.C., Jack, C.R., Grimm, R.C., Rossman, P.J., Felmlee, J.P., Ehman, R.L., Riederer, S.J.: Real-time adaptive motion correction in functional MRI. Magn. Reson. Med. 36, 436–444 (1996)

    Article  Google Scholar 

  • Lee, C.C., Grimm, R.C., Manduca, A., Felmlee, J.P., Ehman, R.L., Riederer, S.J., Jack, C.R.: A prospective approach to correct for inter-image head rotation in FMRI. Magn. Reson. Med. 39, 234–243 (1998)

    Article  Google Scholar 

  • Logothetis, N.K.: The neural basis of the blood-oxygen level dependent functional magnetic resonance imaging signal. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 357(1424), 1003–1037 (2002)

    Article  Google Scholar 

  • McAllister, T.W., Saykin, A.J., Flashman, L.A., Sparling, M.B., Johnson, S.C., Guerin, S.J., Mamourian, A.C., Weaver, J.B., Yanofsky, N.: Brain activation during working memory 1 month after mild traumatic brain injury: A functional MRI study. Neurol. 53, 1300–1308 (1999)

    Article  Google Scholar 

  • McNamee, R.L., Eddy, W.F.: Correlations between cardiac data and fMRI data as a function of spatial frequency and time. In: Proceedings of the 2003 25th Annual International Conference of the IEEE-EMBS Society. Cancun, Mexico (2003)

    Google Scholar 

  • McNamee, R.L., Eddy, W.F.: Examination and removal of the spatial and time-related effects of physiological noise in fMRI data. (in preparation) (2004)

    Google Scholar 

  • Mitra, P.P., Pesaran, B.: Analysis of dynamic brain imaging data. Biophys. J. 78, 691–708 (1999)

    Article  Google Scholar 

  • Ogawa, S., Lee T.-M., Nayak, A.S., Glynn, P.: Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn. Reson. Med. 14, 680–78 (1990)

    Article  Google Scholar 

  • Ogawa, S., Tank, D.W., Menon, D.W., Ellermann, J.M., Kim, S., Merkle, H., Ugurbil, K.: Intrinsic signal changes accompanying sensory stimulation: Functional brain mapping using MRI. Proc. Natl. Acad. Sci. USA 89, 5951–5955 (1992)

    Article  Google Scholar 

  • Poldrack, R.A.: Imaging brain plasticity: Conceptual and methodological issues – A theoretical review. NeuroImage 12, 1–13 (2000)

    Article  Google Scholar 

  • Rosen, A.C., Prull, M.W., O’Hara, R., Race, E.A., Desmond, J.E., Glover, G.H., Yesavage, J.A., Gabrieli, J.D.: Variable effects of aging on frontal lobe contributions to memory. NeuroReport 3(8), 2425–2428 (2002)

    Article  Google Scholar 

  • Schneider, W., Noll, D.C., Cohen, J.D.: Functional topographic mapping of the cortical ribbon in human vision with conventional MRI scanners. Nature 365, 150–153 (1993)

    Article  Google Scholar 

  • Stenger, V.A., Peltier, S., Boada, F.E., Noll, D.C.: 3D spiral cardiac/respiratory ordered fMRI data acquisition at 3 Tesla. Magn. Reson. Med. 41, 983–991 (1999)

    Article  Google Scholar 

  • Thulborn, K.R., Waterton, J.C., Matthews, P.M., Radda, G.K.: Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem. Biophys. Acta. 714, 265–270 (1982)

    Article  Google Scholar 

  • Thulborn, K.R.: Visual feedback to stabilize head position for fMRI. Magn. Reson. Med. 41, 1039–1043 (1999)

    Article  Google Scholar 

  • Turner, R.: Functional mapping of the human brain with magnetic resonance imaging. Sem. Neurosci. 7, 179–194 (1995)

    Article  Google Scholar 

  • Villringer, A.: Physiological Changes During Brain Activation. In: Moonen, C.T.W., Bandettini, P.A. (eds.) Functional MRI, Springer, Berlin (2000)

    Google Scholar 

  • Weisskoff, R.M.: Simple measurement of scanner stability for functional NMR imaging of activation in the brain. Magn. Reson. Med. 36, 643–645 (1996)

    Article  Google Scholar 

  • Weisskoff, R.M., Kiihne, S.: MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood. Magn. Reson. Med. 24, 375–83 (1992)

    Article  Google Scholar 

  • Woods, R., Cherry, S., Mazziotta, J.: Rapid automated algorithm for aligning and reslicing PET images. J. Comp. Ass. Tomog. 16, 620–633 (1992)

    Article  Google Scholar 

  • Wowk, B., McIntyre, M.C., Saunders, J.K.: k-space detection and correction of physiological artifacts in fMRI. Magn. Reson. Med. 38, 1029–1034 (1997)

    Article  Google Scholar 

  • Zeffiro, T.: Clinical functional image analysis: Artifact detection and reduction. NeuroImage 4, S95–S100 (1996)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Statistics, Carnegie Mellon University, Pittsburgh, PA, USA

    William F. Eddy & Rebecca L. McNamee

Authors
  1. William F. Eddy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rebecca L. McNamee
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to William F. Eddy .

Editor information

Editors and Affiliations

  1. Dept. Computational & Data, Sciences, George Mason University, University Drive 4400, Fairfax, 22030-4444, Virginia, USA

    James E. Gentle

  2. L.v.Bortkiewicz Chair of Statistics, C.A.S.E. Centre f. Appl. Stat. & Econ., Humboldt-Universität zu Berlin, Unter den Linden 6, Berlin, 10099, Germany

    Wolfgang Karl Härdle

  3. Dept. Socioinformation, Okayama University, Ridai-cho 1-1, Okayama, 700-0005, Japan

    Yuichi Mori

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Eddy, W.F., McNamee, R.L. (2012). Functional Magnetic Resonance Imaging. In: Gentle, J., Härdle, W., Mori, Y. (eds) Handbook of Computational Statistics. Springer Handbooks of Computational Statistics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21551-3_37

Download citation

Publish with us

Policies and ethics

Search

Navigation