Zusammenfassung
Die Abklärung einer möglichen fetalen Anämie hat bei Blutgruppensensibilisierungen, bei anämisierenden Infektionen (Parvovirus), bei fetomaternaler Transfusion sowie bei Hinweiszeichen im Rahmen der Ultraschalluntersuchung (Hydrops fetalis) oder bei auffälligen, anämieverdächtigen fetalen Herzfrequenzmustern zu erfolgen. Die Diagnosestellung der Anämie erfolgt mittels Chordozentese; diese ist zuverlässig und bietet den Vorteil der gleichzeitigen Abnahmemöglichkeit von fetalem Blut für verschiedene Labortests, um die Ursache der Anämie festzustellen bzw.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
ACOG Practice Bulletin (2006) No. 75: management of alloimmunization. Obstet Gynecol, Aug 2006, 108(2) p45764
Bilardo CM, Nicolaides KH, Campbell S (1989) Doppler studies in red cell isoimmunization. Clin Obstet Gynecol 32: 719727
Copel JA, Grannum PA, Belanger K et al. (1988) Pulsed Doppler flowvelocity waveforms before and after intravascular transfusion for severe erythroblastosis fetalis. Am J Obstet Gynecol 158: 768774
Copel JA, Grannum PA, Green JJ et al. (1989) Pulsed Doppler flow-velocity waveforms in the prediction of fetal hematocrit of the severly isoimmunized pregnancy. Am J Obstet Gynecol 161: 341344
Copel JA, Grannum PA, Green JJ et al. (1989) Fetal cardiac output in the isoimmunized pregnancy: a pulsed Doppler-echocardiographic study of patients undergoing intravascular intrauterine transfusion. Am J Obstet Gynecol 161: 361365
Deren O, Onderoglu L (2002) The value of middle cerebral artery systolic velocity for initial and subsequent management in fetal anemia. Eur J Obstet Gynecol Reprod Biol 101(1): 2630
Detti L, Mari G, Akiyama M, et al. (2002) Longitudinal assessment of the middle cerebral artery peak systolic velocity in healthy fetuses and in fetuses at risk for anemia. Am J Obstet Gynecol 187(4): 9379
Detti L, Oz U, Guney I, et al. (2001) Doppler ultrasound velocimetry for timing the second intrauterine transfusion in fetuses with anemia from red cell alloimmunization. Am J Obstet Gynecol 185(5): 104851
Economides DL, Selinger M, Ferguson J et al. (1992) Computerized measurements of heart rate variation in fetal anemia caused by rhesus alloimmunization. Am J Obstet Gynecol 167: 689683
Giles WB, Trudinger BJ (1986) Umbilical cord whole blood viscosity and the umbilical artery flow velocity time waveforms: a correlation. Br J Obstet Gynaecol 93: 466470
Gill RW, Warren PS, Kossof G et al. (1984) Umbilical venous flow in normal and complicated pregnancy. Ultrasound Med Biol 10: 346363
Grannum PA, Copel JA, Moya FR et al. (1988) The reversal of hydrops fetalis by intravascular intrauterine transfusion in severe isoimmune fetal anemia. Am J Obstet Gynecol 158: 914919
Hecher K, Snijders R, Campbell S et al. (1995) Fetal venous, arterial, and intracardiac bloow flows in red cell isoimmunization. Obstet Gynecol 85: 122128
Huikshoven FJ, Hope ID, Power GG et al. (1985) A comparison of sheep and human fetal oxygen delivery systems with use of a mathematical model. Am J Obstet Gynecol 151: 449455
Jouppila P, Kirkinen P (1984) Umbilical vein blood flow in the human fetus in cases of maternal and fetal anemia and uterine bleeding. Ultrasound Med Biol 10: 365370
Jouppila P, Kirkinen P, Puukka R (1986) Correlation between umbilical vein blood flow and umbilical blood viscosity in normal and complicated pregnancies. Arch Gynecol 237: 191197
Krikinen P, Jouppila P (1983) Umbilical vein blood flow in rhesusisoimmunization. Br J Obstet Gynecol 90: 640643
Makh DS, Harman CR, Baschat AA (2003) Is Doppler prediction of anemia effective in the growth-restricted fetus? Ultrasound Obstet Gynecol 22(5): 48992
Mari G, Adrignolo A, Abuhamad AZ et al. (1995) Diagnosis of fetal anemia with Doppler ultrasound in the pregnancy complicated by maternal blood group immunization. Ultrasound Obstet Gynecol 5: 400405
Mari G, Rahman F, Olofsson P et al. (1997) Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by Rhesus alloimmunization. J Maternal-Fetal Med 6: 206208
Mari G, Deter RL, Carpenter RL, et al. (2000) Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses. N Engl J Med 6;342(1): 914
Moise KJ (2008) Management of rhesus alloimmunization in pregnancy. Obstet Gynecol 112(1): 16476
Moise KJ et al. (2009) Management of Rhesus alloimmunization in pregnancy. UpToDate 18.1.2009
Nicolaides KH, Fontanarosa M, Grabbe SG et al (1988) Failure of ultrasonographic parameters to predict the severity of fetal anemia in rhesus isoimmunization. Am J Obstet Gynecol 158: 920926
Nicolaides KH, Bilardo CM, Campbell S (1990) Prediction of fetal anemia by measurement of the mean blood velocity in the fetal aorta. Am J Obstet Gynecol 162: 209212
Oepkes D, Vandenbussche FP, Van Bel F et al (1993) Fetal ductus venosus blood flow velocities before and after transfusion in red cell alloimmunized pregnancies. Obstet Gynecol 82: 237241
Oepkes D, Seaward PG, Vandenbussche FP, et al. (2006) Doppler ultrasonography versus amniocentesis to predict fetal anemia. N Engl J Med 355(2): 15664
Pretlove SJ, Fox CE, Khan KS, et al. (2009) Noninvasive methods of detecting fetal anaemia: a systematic review and meta-analysis. BJOG 116(12): 155867
Rightmire DA, Nicolaides KH, Rodeck CH et al (1986) Fetal blood velocities in Rh isoimmunization: Relationship to gestational age and to fetal hematocrit. Obstet Gynecol 68: 233236
Rizzo G, Nicolaides KH, Arduini D et al (1990) Effects of intravascular fetal blood transfusion on fetal intracardiac Doppler velocity waveforms. Am J Obstet Gynecol 163: 12311238
Scheier M, Hernandez-Andrade E, Carmo A, Dezerega V, Nicolaides KH (2004) Prediction of fetal anemia in rehesus disease by measurement of fetal middle cerebral peak systolic velocity. Ultrasound Obstet Gynecol 23: 4326
Scheier M, Hernandez-Andrade E, Fonseca EB, et al. (2006) Prediction of severe fetal anemia in red blood cell alloimmunization after previous intrauterine transfusions. Am J Obstet Gynecol 195(6): 15506
Spinnato JA (1992) Hemolytic disease of the fetus: a plea for restraint. Obstet Gynecol 80: 873877
Steiner H, Schaffer H, Spitzer D et al. (1995) The relationship between peak velocity in the fetal descending aorta and hematocrit in rhesus isoimmunization. Obstet Gynecol 85: 659662
Steiner H, Schaffer H, Spitzer D et al. (1995) Überwachung von Nabelschnurpunktionen und intravaskulären Transfusionen mittels Dopplersonographie. Geburtshilfe Frauenheilkd 55: 204206
Warren PS, Gill RW, Fisher CC (1987) Doppler flow studies in rhesus isoimmunization. Semin Perinatol 11: 375378
Weiner CP, Williamson RA, Wenstrom KD et al. (1991) Management of fetal hemolytic disease by cordocentesis: 1. Prediction of fetal anemia. Am J Obstet Gynecol 165: 546553
Weiner CP (1993) Umbilical pressure measurement in the evaluation of nonimmune hydrops. Am J Obstet Gynecol 168: 347352
Weiner CP (1994) Fetal hemolytic disease. In: James DK, Steer PJ, Weiner CP, Gonik B High risk pregnancy. WB Saunders, London Philadelphia, pp 783801
Zimmermann R, Durig P, Carpenter RJ, Mari G (2002) Longitudinal measurement of peak systolic velocity in the fetal middle cerebral artery for monitoring pregnancies complicated by red-cell alloimmunization - a prospective multi-center trial with intention to treat. BJOG 109: 74652
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Steiner, H., Hasenöhrl, G. (2012). Anämie – Blutgruppensensibilisierung. In: Steiner, H., Schneider, KT. (eds) Dopplersonographie in Geburtshilfe und Gynäkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20938-3_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-20938-3_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-48208-7
Online ISBN: 978-3-642-20938-3
eBook Packages: Medicine (German Language)