Zusammenfassung
Krankheiten des Kreislaufsystems sind in der Bundesrepublik Deutschland mit einem Anteil von nahezu 50 % die häufigste Todesursache. Von den Todesfällen als Folge von Kreislauferkrankungen entfallen auf die koronare Herzkrankheit (KHK) insgesamt mehr als 40 %, davon auf das akute Koronarsyndrom (»Acute coronary syndrome«, ACS), speziell auf den akuten Myokardinfarkt (MI), 20 %. Bezogen auf den MI sind dies etwa 75.000 Todesfälle pro Jahr. Als Folge des MI entwickelt sich bei bis zu 50 % der Überlebenden eine chronische Herzinsuffizienz, die gemeinsam mit der chronischen Herzinsuffizienz anderer Genese (z. B. chronische KHK, Kardiomyopathie, Hypertonie, Myokarditis, Herzklappenerkrankungen, Herzrhythmusstörungen, Anämie) mit steigendem Lebensalter zur Haupttodesursache der Bevölkerung in den westlichen Ländern wird. In der Gesamtbevölkerung nimmt die Prävalenz von <1 % (im Alter zwischen 45 und 55 Jahren) auf 2–5 % (65–75 Jahre) und schließlich bei über 80-Jährigen auf fast 10 % zu.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Antman EM, Anbe DT, Armstrong PW et al. (2004) ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction – executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 44: 671–719; erratum in: J Am Coll Cardiol 2005; 45: 1376
Anwaruddin S, Lloyd-Jones DM, Baggish A et al. (2006) Renal function, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement: results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) Study. J Am Coll Cardiol 47: 91–97
Apple FS, Wu AHB, Jaffe AS (2002) European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: How to use existing assays clinically and for clinical trials. J Am Heart 144: 981–986
AWMF online (2008) Diagnostik und Therapie der Bein- und Beckenvenenthrombose und Lungenembolie. Leitlinien Angiologie 2008; www.leitlinien.net. Letzte Überarbeitung: 06/2010
Braunwald E, Antman EM, Beasley JW et al. (2002) ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction – summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol 40: 1366–1374
Christenson RH on behalf of the Committee on Evidence Based Laboratory Medicine of the International Federation for Clinical Chemistry Laboratory Medicine (2007) Evidencebased laboratory medicine – a guide for critical evaluation of in vitro laboratory testing. Ann Clin Biochem 44: 111–130
Harrison A, Amundson S (2005) Evaluation and management of the acutely dyspneic patient: the role of biomarkers. Am J Emerg Med 23: 371–378
Hunt SA, Abraham WT, Chin MH et al. (2005) American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American College of Chest Physicians; International Society for Heart and Lung Transplantation; Heart Rhythm Society. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure), developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation 112: 154–235
Karakas M, Januzzi JL Jr, Meyer J, Lee H, Schlett CL, Truong QA et al (2011) Copeptin Does Not Add Diagnostic Information to High-Sensitivity Troponin T in Low- to Intermediate-Risk Patients with Acute Chest Pain: Results from the Rule Out Myocardial Infarction by Computed Tomography (ROMICAT) Study. Clin Chem;57: 1137–45
Keller T, Tzikas S, Zeller T, Czyz E, Lillpopp L, Ojeda FM et al. (2010) Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol;55: 2096–106
Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E et al. (2009) Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med;361: 868–77
McMurray JJ, Stewart S (2000) Epidemiology, aetiology, and prognosis of heart failure. Heart 83: 596–602
Meyer G, Roy PM, Sors H (2003) Laboratory tests in the diagnosis of pulmonary embolism. Respiration 70: 125–132
Panteghini M, Pagani F, Yeo KT et al. (2004) Committee on Standardization of Markers of Cardiac Damage of the IFCC. Evaluation of imprecision for cardiac troponin assays at low-range concentrations. Clin Chem 50: 327–332
Reichlin T, Hochholzer W, Stelzig C, Laule K, Freidank H, Morgenthaler NG et al. (2009) Incremental value of copeptin for rapid rule out of acute myocardial infarction. J Am Coll Cardiol;54: 60–8
Remme WJ, Swedberg K (2001) Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 22: 1527–1560
Ryan RJ, Lindsell CJ, Hollander JE, O’Neil B, Jackson R, Schreiber D, Christenson R, Gibler WB (2009) A multicenter randomized controlled trial comparing central laboratory and point-of-care cardiac marker testing strategies: the Disposition Impacted by Serial Point of Care Markers in Acute Coronary Syndromes (DISPO-ACS) trial. Ann Emerg Med;53: 321–8
Tang WH, Francis GS, Morrow DA et al. (2007) National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Clinical utilization of cardiac biomarker testing in heart failure. Circulation 116: 99–109
The Joint European Society of Cardiology/American College of Cardiology Committee (2000) Myocardial infarction redefined – A consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the Redefinition of Myocardial Infarction. Eur Heart J 21: 1502–1513
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Giannitsis, E., Luppa, P.B., Peetz, D., Schimke, I. (2012). POCT in der Diagnostik kardiovaskulärer Krankheiten. In: Luppa, P.B., Schlebusch, H. (eds) POCT – Patientennahe Labordiagnostik. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20172-1_17
Download citation
DOI: https://doi.org/10.1007/978-3-642-20172-1_17
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-20171-4
Online ISBN: 978-3-642-20172-1
eBook Packages: Life Science and Basic Disciplines (German Language)