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Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology

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Adipose Stem Cells and Regenerative Medicine

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Abstract

The clinical potential for adipose-derived stem cell (ASC) is abundant and their capacity to differentiate into multiple lineages demonstrates the impact they can provide to regenerative therapies in otolaryngology – head and neck surgery. Adipose tissues have sufficient amounts of ASCs that can be derived from a single sample and harvested with minimally invasive procedures. Furthermore, ASCs can prevent the incidence of graft versus host disease by suppressing the immune response. Tissue engineering strategies can combine cell delivery with appropriate scaffold biomaterials that can mimic the unique physiological and biomechanical properties of ear, nose and throat. This chapter presents a review of the literature regarding the use of ASCs in otolaryngology head and neck surgery related research, illustrating their current and potential use in the field.

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Authors and Affiliations

  1. Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin - Madison, K4/709 600 Highland Ave, Madison, WI, 53792-7375, USA

    Suzanne N. King & Susan Thibeault

Authors
  1. Suzanne N. King
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  2. Susan Thibeault
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Corresponding author

Correspondence to Susan Thibeault .

Editor information

Editors and Affiliations

  1. Plastic Surgery, Suchet 14 BD, Paris, 75016, France

    Yves-Gerard Illouz

  2. Regenerative Plastic Surgery Department, IASO General Hospital, Mesogeion Avenue 264, Athens, 15562, Greece

    Aris Sterodimas

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© 2011 Springer-Verlag Berlin Heidelberg

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King, S.N., Thibeault, S. (2011). Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology. In: Illouz, YG., Sterodimas, A. (eds) Adipose Stem Cells and Regenerative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20012-0_19

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  • DOI: https://doi.org/10.1007/978-3-642-20012-0_19

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-20011-3

  • Online ISBN: 978-3-642-20012-0

  • eBook Packages: MedicineMedicine (R0)

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