Skip to main content

Nanobiosensors and Their Applications

  • Chapter
  • First Online:
Metal Nanoparticles in Microbiology

Abstract

At present, the structuring of researches and their results has become more well defined with the development of a new scientific trend – nanotechnology . To a considerable degree, it is based on discoveries and advances of two decades that led to the development of novel instrumental methods ensuring the possibility of working with nanosized structures. Many developments, previously known as related to biosensors, now have their own niche – nanobiosensorics. The present chapter, taking into account the new division, considers both trends: bio- and nanobiosensors . The objective of this chapter is to distinguish biosensor elements that could be applicable for the creation of nanobiosensors, provided that such transition would improve the parameters of analyzing devices as a whole.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abdullin TI, Nikitina II, Ishmukhametova DG, Budnikov GK, Konovalova OA, Salakhov MK (2007) Carbon nanotube-modified electrodes for electrochemical DNA-sensors. J Anal Chem Russ 62:599–603

    CAS  Google Scholar 

  • Abramova N, Bratov A (2009) Photocurable polymers for ion selective field effect transistors. 20 years of applications. Sensors 9:7097–7110

    Article  CAS  Google Scholar 

  • Cai J, DuBow MS (1997) Use of a luminescent bacterial biosensor for biomonitoring and characterization of arsenic toxicity of chromated copper arsenate (CCA). Biodegradation 8:105–111

    Article  PubMed  CAS  Google Scholar 

  • Chaudri AM, Lawlor K, Preston S, Paton GI, Killham K, McGrath SP (2000) Response of a Rhizobium-based luminescence biosensor to Zn and Cu in soil solutions from sewage sludge treated soils. Soil Biol Biochem 32:383–388

    Article  CAS  Google Scholar 

  • Chen Z-G (2007) Conductometric immunosensors for the detection of staphylococcal enterotoxin B based bio-electrocalytic reaction on micro-comb electrodes. Bioprocess Biosyst Eng 31:345–350

    Article  PubMed  Google Scholar 

  • Cheng Y, Liu Y, Huang J, Li K, Xian Y, Zhang W, Jin L (2008) Amperometric tyrosinase biosensor based on Fe3O4 nanoparticles-coated carbon nanotubes nanocomposite for rapid detection of coliforms. Electrochim Acta 54:2588–2594

    Article  Google Scholar 

  • Cheran L-E, Cheung S, Wang X, Thompson M (2008) Probing the bioelectrochemistry of living cells. Electrochim Acta 53:6690–6697

    Article  CAS  Google Scholar 

  • Dubacheva GV, Porus MV, Sokolovskaya LG, Sigolaeva LV, Pergushev DV, Yaroslavov AA, Eremenko AV, Kurochkin IN, Varfolomeev SD (2007) Nanostructural polyelectrolyte films for highly sensitive tyrosinase biosensors constructing. Nanotechnol Rus 2:154–159

    Google Scholar 

  • Eremeev NL, Kazanskaya NF (1999) Linked enzyme reactions producing responses in stimulus-sensitive polymer systems. Sensornye Sist 13:239–245

    Google Scholar 

  • Evdokimov YM, Zakharov MA, Skuridin SG (2006) Nanotechnology based on nucleic acids. Her Russ Acad Sci 1:5–11

    Article  Google Scholar 

  • Evtushenko EG, Kurochkin IN, Doncova EA, Budashov IA, Eremenko AV, Golovachenko VA, Polyncev DG, Tur DR, Pergushov DV, Papkov IS, Zezin AB, Varfolomeev SD (2007) Antibody nanofilms based on polyelectrolytes for extremely sensitive immunoassays. Nanotechnol Rus 2:145–153

    Google Scholar 

  • Gruner G (2006) Carbon nanotube transistors for biosensing applications. Anal Bioanal Chem 384:322–335

    Article  PubMed  CAS  Google Scholar 

  • Hasunuma T, Kuwabata S, Fukusaki E, Kobayashi A (2004) Real-time quantification of methanol in plants using a hybrid alcohol oxidase-peroxidase biosensor. Anal Chem 76:1500–1506

    Article  PubMed  CAS  Google Scholar 

  • Haustein E, Schwille P (2004) Single-molecule spectroscopic methods. Curr Opin Struct Biol 14:531–540

    Article  PubMed  CAS  Google Scholar 

  • Ivanov AB, Kretushev AV, Ignat’ev PS, Vyshenskaya TV, Tychinskii VP (2007) Raster method of localization of nanosized areas of metabolic activity in phase images of cells. Nanotechnol Rus 2:120–125

    Google Scholar 

  • Joung HA, Lee NR, Lee SK, Ahn J, Shin YB, Choi HS, Lee CS, Kim S, Kim MG (2008) High sensitivity detection of 16s rRNA using peptide nucleic acid probes and a surface plasmon resonance biosensor. Anal Chim Acta 630:168–173

    Article  PubMed  CAS  Google Scholar 

  • Kasemets K, Ivask A, Dubourguier HC, Kahru A (2009) Toxicity of nanoparticles of ZnO, CuO and TiO2 to yeast Saccharomyces cerevisiae. Toxicol In Vitro 23:1116–1122

    Article  PubMed  CAS  Google Scholar 

  • Koets M, van der Wijk T, van Eemeren JT, van Amerongen A, Prins MW (2009) Rapid DNA multi-analyte immunoassay on a magneto-resistance biosensor. Biosens Bioelectron 24:1893–1898

    Article  PubMed  CAS  Google Scholar 

  • Kulichihin VG, Antonov SV, Makarova VV, Semakov AV, Singh P (2006) Hydrocolloid adhesives for biomedical application based on nanocomposite concept. Nanotechnol Rus 1:170–182

    Google Scholar 

  • Langer JJ, Langer K, Barczyński P, Warchoł J, Bartkowiak KH (2009) New “ON-OFF”-type nanobiodetector. Biosens Bioelectron 24:2947–2949

    Article  PubMed  CAS  Google Scholar 

  • Lazarev VN, Filatova EV, Levickii SA, Nikolaev EN, Leipunskii IO, Jigach AN, Kuskov ML, Govorun VM (2007) Development of method for purification of recombinant proteins using nickel nanoparticles. Nanotechnol Rus 2:133–140

    Google Scholar 

  • Lee C-S, Kim SK, Kim M (2009) Ion-sensitive field-effect transistor for biological sensing. Sensors 9:7111–7131

    Article  CAS  Google Scholar 

  • Lioubashevski O, Chegel VI, Patolsky F, Katz E, Willner I (2004) Enzyme-catalyzed bio-pumping of electrons into au-nanoparticles: a surface plasmon resonance and electrochemical study. J Am Chem Soc 126:7133–7143

    Article  PubMed  CAS  Google Scholar 

  • LLC SPE “Nanostructed Glass Technology” (2010) Biochips/Products/Main page/LLC SPE “Nanostructed Glass Technology” (LLC SPE “NGT”). http://ngt2005.narod.ru/catalog/Biochipi/. Cited 2 Jan 2010

  • McFarland AD, Van Duyne RP (2003) Single silver nanoparticles as real-time optical sensors with zeptomole sensitivity. Nano Lett 3:1057–1062

    Article  CAS  Google Scholar 

  • Medyantseva EP, Kutyreva MP, Khaldeeva EV, Glushko NI, Budnikov GK (1999) Determination of the Phytophthora infestans antigen with the use of an immunoenzyme amperometric sensor. J Anal Chem Russ 54:1147–1151

    CAS  Google Scholar 

  • Mendelsohn JD (2002) Polyelectrolyte multilayers: nanofabricated architectures for bio-interface materials. Massachusetts Institute of Technology, Department of Materials Science and Engineering, Ph.D. thesis: 135 p.

    Google Scholar 

  • Molchanov SP, Chernova-Kharaeva IA, Abdullaeva SH and Alekperov SD (2004) Electrochemical modification of polyaniline surface using SPM. Proceedings of I International Scientific Seminar “Light in Nanosize Solids”, Baku

    Google Scholar 

  • Momynaliev KT, Lazarev VN, Kostryukova ES, Chelysheva VV, Selezneva OV, Kravchenko EV, Govorun VM (2007) Microfluid technologies for detection of intracellular processes in bacterial cell. Nanotechnol Rus 2:126–132

    Google Scholar 

  • Narváez A, Suárez G, Popescu IC, Katakis I, Domínguez E (2000) Reagentless biosensors based on self-deposited redox polyelectrolyte-oxidoreductases architectures. Biosens Bioelectron 15:43–52

    Article  PubMed  Google Scholar 

  • Nguyen-Vu TDB, Chen H, Cassell AM, Andrews R, Meyyappan M, Li J (2005) Vertically aligned carbon nanofiber arrays: an advance toward electrical-neural interfaces. Small 2:89–94

    Article  Google Scholar 

  • Odaci D, Timur S, Telefoncu A (2008) Bacterial sensors based on chitosan matrices. Sens Actuators B Chem 134:89–94

    Article  Google Scholar 

  • Olejnikov VA, Sukhanova AV, Nabiev IR (2007) Fluorescent semiconductor nanocrystals for biology and medicine. Nanotechnol Rus 2:160–173

    Google Scholar 

  • Plekhanova YV, Reshetilov AN, Yazynina EV, Zherdev AV, Dzantiev BB (2003) A new assay format for electrochemical immunosensors: polyelectrolyte-based separation on membrane carriers combined with detection of peroxidase activity by pH-sensitive field-effect transistor. Biosens Bioelectron 19:109–114

    Article  PubMed  CAS  Google Scholar 

  • Popovtzer R, Neufeld T, Biran D, Ron EZ, Rishpon J, Shacham-Diamand Y (2005) Novel integrated electrochemical nano-biochip for toxicity detection in water. Nano Lett 5:1023–1027

    Article  PubMed  CAS  Google Scholar 

  • Popovtzer R, Neufeld T, Ron EZ, Rishpon J, Shacham-Diamand Y (2006) Electrochemical detection of biological reactions using a novel nano-bio-chip array. Sens Actuators B Chem 119:664–672

    Article  Google Scholar 

  • Qu L, Xia S, Bian C, Sun J, Han J (2009) A micro-potentiometric hemoglobin immunosensor based on electropolymerized polypyrrole-gold nanoparticles composite. Biosens Bioelectron 24:3419–3424

    Article  PubMed  CAS  Google Scholar 

  • Ramanathan S, Ensor M, Daunert S (1997) Bacterial biosensors for monitoring toxic metals. Trends Biotechnol 15:500–506

    Article  PubMed  CAS  Google Scholar 

  • Rasmussen LD, Sorensen SJ, Turner RR, Barkay T (2000) Application of a mer-lux biosensor for estimating bioavailable mercury in soil. Soil Biol Biochem 32:639–646

    Article  CAS  Google Scholar 

  • Reshetilov AN (2007) Biosensor development in Russia. Biotechnol J 2:849–862

    Article  PubMed  CAS  Google Scholar 

  • Reshetilov AN, Efremov DA, Iliasov PV, Boronin AM, Kukushskin NI, Greene RV, Leathers TD (1998) Effects of high oxygen concentrations on microbial biosensor signals. Hyperoxygenation by means of perfluorodecalin. Biosens Bioelectron 13:795–799

    Article  PubMed  CAS  Google Scholar 

  • Risveden K, Ponten JF, Calander N, Willander M, Danielsson B (2007) The region ion sensitive field effect transistor, a novel bioelectronic nanosensor. Biosens Bioelectron 22:3105–3112

    Article  PubMed  CAS  Google Scholar 

  • Ros R, Eckel R, Bartels F, Sischka A, Baumgarth B, Wilking SD, Puhler A, Sewald N, Becker A, Anselmetti D (2004) Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. J Biotechnol 112:5–12

    Article  PubMed  CAS  Google Scholar 

  • Sanvicens N, Pastells C, Pascual N, Marco M-P (2009) Nanoparticle-based biosensors for detection of pathogenic bacteria. Trends Anal Chem 28:1243–1252

    Article  CAS  Google Scholar 

  • Schöning MJ, Poghossian A (2006) Bio FEDs (field-effect devices): state-of-the-art and new directions. Electroanalysis 18:1893–1900

    Article  Google Scholar 

  • Skottrup PD, Nicolaisen M, Justesen AF (2008) Towards on-site pathogen detection using antibody-based sensors. Biosens Bioelectron 24:339–348

    Article  PubMed  CAS  Google Scholar 

  • So HM, Park DW, Jeon EK, Kim YH, Kim BS, Lee CK, Choi SY, Kim SC, Chang H, Lee JO (2008) Detection and titer estimation of Escherichia coli using aptamer-functionalized single-walled carbon-nanotube field-effect transistors. Small 4:197–201

    Article  PubMed  CAS  Google Scholar 

  • Stern E, Klemic JF, Routenberg DA, Wyrembak PN, Turner-Evans DB, Hamilton AD, LaVan DA, Fahmy TM, Reed MA (2007) Label-free immunodetection with CMOS-compatible semiconducting nanowires. Nature 445:519–522

    Article  PubMed  CAS  Google Scholar 

  • Timur S, Anik U, Odaci D, Gorton L (2007) Development of a microbial biosensor based on carbon nanotube (CNT) modified electrodes. Electrochem Commun 9:1810–1815

    Article  CAS  Google Scholar 

  • Turner APF, Karube I, Wilson GS (eds) (1987) Biosensors: fundamentals and applications. Oxford University Press, New York

    Google Scholar 

  • V.A. Engelgardt Institute of Molecular Biology Russian Academy of Sciences (2010) Laboratory of biological microchips. http://www.biochip.ru/en/index.html. Cited 2 Jan 2010

  • Vijayalakshmi A, Tarunashree Y, Baruwati B, Manorama SV, Narayana BL, Johnson RE, Rao NM (2008) Enzyme field effect transistor (ENFET) for estimation of triglycerides using magnetic nanoparticles. Biosens Bioelectron 23:1708–1714

    Article  PubMed  CAS  Google Scholar 

  • Villamizar RA, Maroto A, Rius FX, Inza I, Figueras MJ (2008) Fast detection of Salmonella Infantis with carbon nanotube field effect transistors. Biosens Bioelectron 24:279–283

    Article  PubMed  CAS  Google Scholar 

  • Vogel V, Baird B (2003) Nanobiotechnology. In: National Nanotechnology Initiative Workshop. October 9–11, Arlington, VA, USA: pp 1–106

    Google Scholar 

  • Zasedatelev A, Nasedkina T, Rubina A, Gryadunov D (2006) In: Proceedings of NATO advanced research workshop “commercial and pre-commercial cell detection technologies for defense against bioterror – technology, market and society”, Brno, Czech Republic

    Google Scholar 

Download references

Acknowledgments

The work was partially supported by the grant for research work in the scope of Federal target program “Scientific and research-pedagogic personnel of innovative Russia” for 2009–2013 (GK NK-no. 37(4)).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. Reshetilov .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Reshetilov, A., Iliasov, P., Reshetilova, T., Rai, M. (2011). Nanobiosensors and Their Applications. In: Rai, M., Duran, N. (eds) Metal Nanoparticles in Microbiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18312-6_12

Download citation

Publish with us

Policies and ethics