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Interventional Radiological Procedures for Port-Catheter Implantation

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Induction Chemotherapy

Abstract

In the past the role of hepatic arterial infusion chemotherapy has not been widely accepted. At the present time it is used in very limited situations, because its efficacy has not been established by randomized trials comparing it with systemic chemotherapy. However, in these trials, only surgical procedures have been employed for port-catheter implantation. On the other hand, interventional radiological procedures for port-catheter implantation have been well established, and they allow minimally invasive and accurate hepatic arterial infusion chemotherapy. In this chapter, the concept and technical details of interventional radiological procedures for port-catheter implantation and the technical and therapeutic results in hepatic arterial infusion chemotherapy are described. Additionally, new interventional radiological procedures and therapeutic results in the treatment of locally advanced breast cancer are also mentioned.

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References

  1. Kemeny MM, Goldberg DA, Browning S, Metter GE, et al. Experience with continuous regional chemotherapy and hepatic resection as treatment of hepatic metastases from colorectal primaries. A prospective randomized study. Cancer. 1985;55:1265–70.

    Article  PubMed  CAS  Google Scholar 

  2. Chang AE, Schneider PD, Sugarbaker PH, et al. A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg. 1987;206:685–93.

    Article  PubMed  CAS  Google Scholar 

  3. Kemeny N, Daly J, Reichman B, Geller N, et al. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma. A randomized trial. Ann Intern Med. 1987;107:459–65.

    PubMed  CAS  Google Scholar 

  4. Hohn DC, Stagg RJ, Friedman MA, Hannigan Jr JF, et al. A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California Oncology Group trial. J Clin Oncol. 1989;7:1646–54.

    PubMed  CAS  Google Scholar 

  5. Martin JK, O’Connell MJ, Wieand HS, Fitzgibbons Jr RJ, et al. Intra-arterial floxuridine vs. systemic fluorouracil for hepatic metastases from colorectal cancer. A randomized trial. Arch Surg. 1990;125:1022–7.

    Article  PubMed  Google Scholar 

  6. Rougier P, Laplanche A, Huguier M, Hay JM, et al. Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial. J Clin Oncol. 1992;10:1112–8.

    PubMed  CAS  Google Scholar 

  7. Allen-Mersh TG, Earlam S, Fordy C, et al. Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastases. Lancet. 1994;344:1255–60.

    Article  PubMed  CAS  Google Scholar 

  8. Lorenz M, Muller HH. Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colorectal carcinoma. J Clin Oncol. 2000;18:243–54.

    PubMed  CAS  Google Scholar 

  9. Allen-Mersh TG, Glover C, Fordy C, et al. Randomized trial of regional plus systemic fluorinated pyrimidine compared with systemic fluorinated pyrimidine in treatment of colorectal liver metastases. Eur J Surg Oncol. 2000;26:468–73.

    Article  PubMed  CAS  Google Scholar 

  10. Kerr DJ, McArdle CS, Ledermann J, et al. Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial. Lancet. 2003;361:368–73.

    Article  PubMed  CAS  Google Scholar 

  11. Begos DG, Ballantyne GH. Regional chemotherapy for colorectal liver metastases: thirty years without patient benefit. J Surg Oncol. 1994;56:139–44.

    Article  PubMed  CAS  Google Scholar 

  12. Meta-analysis Group of Cancer. Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. J Natl Cancer Inst. 1996;88:252–8.

    Article  Google Scholar 

  13. Arai Y, Inaba Y, Takeuchi Y. Interventional techniques for hepatic arterial infusion chemotherapy. In: Wilfrido R, Castaneda-Zuniga, editors. Interventional radiology. Baltimore: Williams and Wilkins; 1997. p. 192–205.

    Google Scholar 

  14. Arai Y, Takeuchi Y, Inaba Y, et al. Percutaneous catheter placement for hepatic arterial infusion chemotherapy. Tech Vasc Interv Radiol. 2007;10:30–7.

    Article  PubMed  Google Scholar 

  15. Ganeshan A, Upponi S, Hon LQ, et al. Hepatic arterial infusion of chemotherapy: the role of diagnostic and interventional radiology. Ann Oncol. 2008;19:847–51.

    Article  PubMed  CAS  Google Scholar 

  16. Kemeny N, Jarnagin W, Paty P, et al. Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from ­colorectal cancer. J Clin Oncol. 2005;23:4888–96.

    Article  PubMed  CAS  Google Scholar 

  17. Ducreux M, Ychou M, Laplanche A, et al. Hepatic arterial oxaliplatin infusion plus intravenous chemotherapy in colorectal cancer with inoperable hepatic metastases: a trial of the gastrointestinal group of the Federation Nationale des Centres de Lutte Contre le Cancer. J Clin Oncol. 2005;23:4881–7.

    Article  PubMed  CAS  Google Scholar 

  18. Obi S, Yoshida H, Toune R, et al. Combination therapy of intraarterial 5-fluorouracil and systemic interferon-alpha for advanced hepatocellular carcinoma with portal venous invasion. Cancer. 2006;106:1990–7.

    Article  PubMed  CAS  Google Scholar 

  19. Seki H, Ozaki T, Takaki S, et al. Using slow-infusion MR arteriography and an implantable port system to assess drug distribution at hepatic arterial infusion chemotherapy. AJR Am J Roentgenol. 2003;180:681–6.

    PubMed  Google Scholar 

  20. Seki H, Kimura M, Yoshimura N, et al. Hepatic arterial infusion chemotherapy using percutaneous catheter placement with an implantable port: assessment of factors affecting patency of the hepatic artery. Clin Radiol. 1999;54:221–7.

    Article  PubMed  CAS  Google Scholar 

  21. Yamagami T, Iida S, Kato T, et al. Using n-butyl cyanoacrylate and the fixed-catheter-tip technique in percutaneous implantation of a port-catheter system in patients undergoing repeated hepatic arterial chemotherapy. AJR Am J Roentgenol. 2002;179:1611–7.

    PubMed  Google Scholar 

  22. Tanaka T, Arai Y, Inaba Y, et al. Radiologic placement of side-hole catheter with tip fixation for hepatic arterial infusion chemotherapy. J Vasc Interv Radiol. 2003;14:63–8.

    Article  PubMed  Google Scholar 

  23. Arai Y, Inaba Y, Takeuchi Y, et al. Intermittent hepatic arterial infusion of high-dose 5FU on a weekly schedule for liver metastases from colorectal cancer. Cancer Chemother Pharmacol. 1997;40:526–30.

    Article  PubMed  CAS  Google Scholar 

  24. Arai Y, Inaba Y, Matsueda K, et al. Weekly 5 hour hepatic arterial infusion of high dose 5-FU for unresectable liver metastases from colorectal cancer in patients without extra-hepatic lesions. Proc ASCO. 1998;17:285a.

    Google Scholar 

  25. Arai Y, Sone Y, Tohyama N, et al. Hepatic arterial infusion for unresectable liver metastases from gastric cancer. Proc ASCO. 1992;11:176.

    Google Scholar 

  26. Kumada T, Arai Y, Itoh K, et al. Phase II study of combined administration of 5-fluorouracil, epirubicin and mitomycin-C by hepatic artery infusion in patients with liver metastases of gastric cancer. Oncology. 1999;57:216–23.

    Article  PubMed  CAS  Google Scholar 

  27. Takizawa K, Shimamoto H, Ogawa Y, et al. Development of a new subclavian arterial infusion chemotherapy method for locally or recurrent advanced breast cancer using an implanted catheter-port system after redistribution of arterial tumor supply. Cardiovasc Intervent Radiol. 2009;32:1059–66.

    Article  PubMed  Google Scholar 

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Correspondence to Yasuaki Arai .

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© 2011 Springer-Verlag Berlin Heidelberg

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Arai, Y. (2011). Interventional Radiological Procedures for Port-Catheter Implantation. In: Aigner, K., Stephens, F. (eds) Induction Chemotherapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18173-3_17

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  • DOI: https://doi.org/10.1007/978-3-642-18173-3_17

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