Abstract
LGV is primarily an infection of lymphatics and lymph nodes. Chlamydia trachomatis is the bacteria responsible for LGV. It gains entrance through breaks in the skin, or it can cross the epithelial cell layer of mucous membranes. The organism travels from the site of inoculation down the lymphatic channels to multiply within mononuclear phagocytes of the lymph nodes it passes. LGV may begin as a self-limited painless genital ulcer that occurs at the contact site 3-12 days after infection. Women rarely notice a primary infection because the initial ulceration where the organism penetrates the mucosal layer is often located out of sight, in the vaginal wall.
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Lupi, O., Ribeiro, J., Chicralla, P., Martins, C.J. (2011). Lymphogranuloma Venereum. In: Gross, G., Tyring, S. (eds) Sexually Transmitted Infections and Sexually Transmitted Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14663-3_10
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