Skip to main content
SpringerLink
Log in

Rinsing Therapy of Eye Burns

  • Chapter
  • First Online:
Chemical Ocular Burns

Abstract

This is the essential point of the initial management of ocular chemical splashes, which is here developed and illustrated by new experimental data of the first importance. The following are successively addressed: the mechanisms of diffusion with utilization of a powerful OCT imaging technique, the osmotic effect with measurement of corneal stroma hydration, and finally the effects of irrigation with fluids in various conditions of chemical injury at the epithelial surface. Numerous original graphics illustrate the results of these innovative studies. The main ocular washing products available on the market for decontamination of chemical splashes are compared and some clear conclusions are formulated as to their advantages, efficacy, and adverse effects. Examples of specific decontamination for radicals, peroxides, and hydrofluoric acid conclude the discussion on a practical dimension.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.00
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kuckelkorn, R., Kottek, A., Schrage, N., Reim, M.: Poor prognosis of severe chemical and thermal eye burns: the need for adequate emergency care and primary prevention. Int Arch Occup Environ Health 67(4), 281–284 (1995)

    Article  PubMed  CAS  Google Scholar 

  2. Merle, H., Donnio, A., Ayeboua, L., Michel, F., Thomas, F., Ketterle, J., Leonard, C., Josset, P., Gerard, M.: Alkali ocular burns in Martinique (French West Indies) Evaluation of the use of an amphoteric solution as the rinsing product. Burns 31(2), 205–211 (2005)

    Article  PubMed  Google Scholar 

  3. Kuckelkorn, R., Kottek, A., Reim, M.: Intraocular complications after severe chemical burns-incidence and surgical treatment. Klin Monatsbl Augenheilkd 205(2), 86–92 (1994)

    Article  PubMed  CAS  Google Scholar 

  4. Laux, U., Roth, H.W., Krey, H., Steinhardt, B.: Die Wasserstoffkonzentration des Kammerwassers nach Alkali­verätzungen der Hornhaut und deren therapeutische Beeinflu­ßbarkeit. Eine tierexperimentelle Studie. Albrecht von Graefes Arch Clin Exp Ophthalmol 195(1), 33–40 (1975)

    CAS  Google Scholar 

  5. Rihawi, S., Frentz, M., Schrage, N.F.: Emergency treatment of eye burns: which rinsing solution should we choose? Graefes Arch Clin Exp Ophthalmol 244(7), 845–854 (2006)

    Article  PubMed  CAS  Google Scholar 

  6. Gerard, M., Merle, H., Ayeboua, L., Richer, R.: Prospective study of eye burns at the Fort de France University Hospital. J Fr Ophtalmol 22(8), 834–847 (1999). French

    PubMed  CAS  Google Scholar 

  7. Pfister, R.R., Haddox, J.L., Sommers, C.I., Lam, K.W.: A neutrophil chemoattractant is released from cellular and extracellular components of the alkali-degraded cornea and blood. Invest Ophthalmol Vis Sci 37(1), 230–237 (1996)

    PubMed  CAS  Google Scholar 

  8. Kompa, S., Schareck, B., et al.: Comparison of emergency eye-wash products in burned porcine eyes. Graefes Arch Clin Exp Ophthalmol 240(4), 308–313 (2002)

    Article  PubMed  Google Scholar 

  9. Schrage, N.F., Rihawi, R., Frentz, M., Reim, M.: Acute therapy for eye burns. Klin Monatsbl Augenheilkd. 221(4), 253–261 (2004)

    Article  PubMed  CAS  Google Scholar 

  10. Pospisil, H., Holzhutter, H.G.: A compartment model to calculate time-dependent concentration profiles of topically applied chemical compounds in the anterior compartments of the rabbit eye. Altern Lab Anim 29(3), 347–365 (2001)

    PubMed  CAS  Google Scholar 

  11. Langefeld, S., Reim, M., Redbrake, C., Schrage, N.F.: The corneal stroma, an inhomogenous structure. Graefes Arch Clin Exp Ophthalmol 235(8), 480–485 (1997)

    Article  PubMed  CAS  Google Scholar 

  12. Reim, M.: Surgical anatomy, physiology, biochemistry and questions on the inlay technique. Ophthalmologe 89(2), 109–118 (1992)

    PubMed  CAS  Google Scholar 

  13. Bramsen, T., Ehlers, N.: Early postoperative changes in graft thickness after penetrating keratoplasty. Influence of host corneal disorder on time course. Acta Ophthalmol (Copenh) 57(2), 258–268 (1979)

    Article  CAS  Google Scholar 

  14. Kubota, M., Fagerholm, P.: Corneal alkali burn in the rabbit. Waterbalance, healing and transparency. Acta Ophthalmol (Copenh) 69(5), 635–640 (1991)

    Article  CAS  Google Scholar 

  15. Reim, M. (ed.): Augenheilkunde, 5th edn. Enke, Stuttgart (1996)

    Google Scholar 

  16. Schrage, N.F., Benz, K., Beaujean, P., Burchard, W.G., Reim, M.: A simple empirical calibration of energy dispersive X-ray analysis (EDXA) on the cornea. Scanning Microsc 7(3), 881–888 (1993)

    PubMed  CAS  Google Scholar 

  17. von Fischern, T., Lorenz, U., Burchard, W.G., Reim, M., Schrage, N.F.: Changes in the mineral composition of the rabbit cornea after alkali burns. Graefes Arch Clin Exp Ophthalmol 236(7), 553–558 (1998)

    Article  Google Scholar 

  18. Aslund, F., Berndt, K.D., Holmgren, A.: Redox potentials of glutaredoxins and other thiol-disulfide oxidoreductases of the thioredoxin superfamily determined by direct protein-protein redox equilibria. J Biol Chem 272(49), 30780–30786 (1997)

    Article  PubMed  CAS  Google Scholar 

  19. Spöler, F., Frentz, M., Först, M., Kurz, H., Schrage, N.F.: Analysis of hydrofluoric acid penetration and decontamination of the eye by means of time-resolved optical coherence tomography. Burns 34(4), 549–555 (2008). doi:10.1016/j.burns.2007.05.004

    Article  PubMed  Google Scholar 

  20. Bernauer, W., Thiel, M.A., Kurrer, M., Heiligenhaus, A., Rentsch, K.M., Schmitt, A., Heinz, C., Yanar, A.: Corneal calcification following intensified treatment with sodium hyaluronate artificial tears. Br J Ophthalmol 90(3), 285–288 (2006)

    Article  PubMed  CAS  Google Scholar 

  21. Kompa, S., Redbrake, C., Dunkel, B., Weber, A., Schrage, N.: Corneal calcification after chemical eye burns caused by eye drops containing phosphate buffer. Burns 32(6), 744–747 (2006)

    Article  PubMed  Google Scholar 

  22. Schrage, N.F., Kompa, S., Ballmann, B., Reim, M., Langefeld, S.: Relationship of eye burns with calcifications of the cornea? Graefes Arch Clin Exp Ophthalmol 243(8), 780–784 (2005)

    Article  PubMed  Google Scholar 

  23. Schrage, N.F., Schlossmacher, B., Aschenbernner, W., Langefeld, S.: Phosphate buffer in alkali eye burns as an inducer of experimental corneal calcification. Burns 27(5), 459–464 (2001)

    Article  PubMed  CAS  Google Scholar 

  24. Kompa, S., Redbrake, C., Langefeld, S., Brenman, K., Schrage, N.: The type II Aachen-Keratoprosthesis in humans: case report of the first prolonged application. Int J Artif Organs 24(2), 110–114 (2001)

    PubMed  CAS  Google Scholar 

  25. Pellegrini, G., Traverso, C.E., Franzi, A.T., Zingirian, M., Cancedda, R., De Luca, M.: Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 349(9057), 990–993 (1997)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology of the City Hospital, Augenklinik Köln Merheim, Cologne, Germany

    Norbert Schrage (Head of the Department Professorship at the RWTH Aachen, Foundator of ACTO (Aachen Center of Technology Transfer in Ophthalmology)

Authors
  1. Norbert Schrage
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Norbert Schrage .

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schrage, N. (2011). Rinsing Therapy of Eye Burns. In: Chemical Ocular Burns. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14550-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-14550-6_6

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-14549-0

  • Online ISBN: 978-3-642-14550-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation