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Physiopathology of the Cornea and Physiopathology of Eye Burns

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Chemical Ocular Burns

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Abstract

This is a key chapter for a thorough understanding of what actually occurs with an ocular chemical lesion. It tackles the concepts of physiological barriers and the physiological limits of in situ decontamination. It notes the limits between irritation and corrosion by exploring the pathophysiology of ocular burns in great depth. The various physical mechanisms, thermal and chemical, are compared. The differences between liquid, gaseous, or solid chemical agents are analyzed. This chapter equally explains the influence of osmolarity and the characteristics of penetration of the various chemical agents, as well as the direct measurement of the production of inflammatory mediators during the course of chemical burns in experimental models.

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Authors and Affiliations

  1. Department of Ophthalmology of the City Hospital, Augenklinik Köln Merheim, Cologne, Germany

    Norbert Schrage (Head of the Department Professorship at the RWTH Aachen, Foundator of ACTO (Aachen Center of Technology Transfer in Ophthalmology)

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  1. Norbert Schrage
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Correspondence to Norbert Schrage .

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Schrage, N. (2011). Physiopathology of the Cornea and Physiopathology of Eye Burns. In: Chemical Ocular Burns. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14550-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-14550-6_5

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