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Immunreaktionen gegen Erythrozyten

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Transfusionsmedizin und Immunhämatologie

Zusammenfassung

Erythrozyten tragen zahlreiche spezifische Merkmale (Antigene), die Immunreaktionen stimulieren und durch die Bildung von Antikörpern zur Immunhämolyse führen können. Der Nachweis und die Klassifizierung einer Immunhämolyse gestalten sich häufig schwierig, eine Verkennung der Diagnose jedoch kann bei einer schweren Hämolyse zum Tod führen.

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Notes

  1. 1.

    IgM-Autoantikörper lassen sich serologisch nicht immer nachweisen. Hinweisend auf IgM-Autoantikörper ist häufig nur die C3d-Positivität im Coombs-Test.

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Authors and Affiliations

  1. Campus Virchow-Klinikum Institut für Transfusionsmedizin, Universitätsklinikum Charité, Augustenburger Platz 1, 13353, Berlin

    Prof. Dr. A. Salama

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  1. Prof. Dr. A. Salama
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  1. Abteilung für Transfusionsmedizin, Universitätsklinikum Rostock AöR, Ernst-Heydemann-Str. 6, 18057, Rostock

    Volker Kiefel

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Salama, A. (2010). Immunreaktionen gegen Erythrozyten. In: Kiefel, V., Mueller-Eckhardt, C. (eds) Transfusionsmedizin und Immunhämatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12765-6_6

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  • DOI: https://doi.org/10.1007/978-3-642-12765-6_6

  • Publisher Name: Springer, Berlin, Heidelberg

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