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Unicompartmental Knee Arthroplasty

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European Instructional Lectures

Part of the book series: European Instructional Lectures ((EICL,volume 10))

Abstract

All biological tissues contain matrix, cells, and water. In articular cartilage the matrix is a complex structure within which the chondrocytes are distributed in a recognisable pattern. The matrix contains principally type II collagen bundles with attached and unattached proteoglycan complexes. The latter contain aggrecan (proteoglycan) and glycosaminoglycan (GAG). Aggrecan comprises a hyaluronan molecule which is linked through keratin and chondroitin sulphate molecules to form a series of “bottle-brushes” on either side of the hyaluronan chain. Aggrecan is extremely hydrophilic, attracting water. This increases tissue tension and the water is contained by the large-diameter collagen bundles. The arrangement of the bundles is shown schematically in Fig. 1 [8].

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Donell, S.T. (2010). Unicompartmental Knee Arthroplasty. In: Bentley, G. (eds) European Instructional Lectures. European Instructional Lectures, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11832-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-11832-6_15

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