Abstract
The prevalence of nasal polyps (NP) in the population has been grossly estimated as 1–4%. An association between NP and allergic rhinitis (AR) is weak, with NP prevalence in patients with AR estimated between 1.5 and 1.7% and this incidence approaches that of the general population. Large cohort studies have revealed a strong association between asthma and NP. The incidence of NP increases with age and is likely the greatest between 40 and 60 years of age. If NP are found in a child, a workup for cystic fibrosis should be conducted. Genetic inheritance has been proposed as a possible etiology of NP but remains unclear. Up to 50% of aspirin insensitive patients have NP and up to 36% of patients with NP may have some form of analgesic insensitivity. Allergic fungal rhinosinusitis is a known underlying pathophysiologic etiology in a subset of CRS patients and is strongly associated with NP. Ethnic and geographic variation has emerged as a potential modifier in NP pathophysiology.
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Pearlman, A.N., Chandra, R.K., Conley, D.B., Kern, R.C. (2010). Epidemiology of Nasal Polyps. In: Önerci, T., Ferguson, B. (eds) Nasal Polyposis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11412-0_2
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