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Nebenhoden, Hodenhüllen und Samenstrang

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Pathologie

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Zusammenfassung

Das Kapitel beschäftigt sich mit allen Erkrankungen des Nebenhodens, der Hodenhüllen und des Samenstrangs. Im Vordergrund stehen die Missbildungen des Samenstrangs und des Nebenhodens sowie die Veränderungen nach Vasektomie. Neben den Entzündungen und den seltenen epithelialen Nebenhodentumoren werden vor allem die häufigen mesothelialen Tumoren des Nebenhodens und der Hodenhüllen besprochen.

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Literatur

  1. Ahmed M, Chari R, Mufi GR, Azzopardi A (1996) Malignant mesothelioma of the tunica vaginalis testis diagnosed by aspiration cytology – a case report with review of literature. Int Urol Nephrol 28:793–796

    Article  CAS  PubMed  Google Scholar 

  2. Amin MB (2005) Selected other problematic testicular and paratesticular lesions: rete testis neoplasm’s and pseudotumors, mesothelial lesions and secondary tumors. Mod Pathol 18:S131–S145

    Article  PubMed  Google Scholar 

  3. Anguiano A, Oates RD, Amos JA, Dean M, Gerrard B, Stewart C, Maher TA, White MB, Milunsky (1992) A Congenital bilateral absence of the vas deferens. A primarily genital form of cystic fibrosis. JAMA 267:1794–1797

    Article  CAS  PubMed  Google Scholar 

  4. Attanoos RL, Gibbs AR (2000) Primary malignant gonadal mesotheliomas and asbestos. Histopathology 37:150–159

    Article  CAS  PubMed  Google Scholar 

  5. Benjamin JA, Robertson TD, Cheetham JG (1943) Vasitis nodosa: a new clinical entity simulating tuberculosis of the vas deferens. J Urol 49:575–582

    Google Scholar 

  6. Boorjian S, Lipkin M, Goldstein M (2004) The impact of obstructive interval and sperm granuloma on outcome of vasectomy reversal. J Urol 171:304–306

    Article  PubMed  Google Scholar 

  7. Bösmüller H, von Weyheren CH, Adam P, Alibegovic V, Mikuz G, Fend F (2011) Paratesticular fibrous tumor: An IgG4 related disorder. Virchows Arch 458:109–113

    Article  PubMed  Google Scholar 

  8. Broderick GA, Tom R, McClure RD (1989) Immunological status of patients before and after vasovasostomy as determined by the immunobead antisperm antibody test. J Urol 142:752–755

    CAS  PubMed  Google Scholar 

  9. Bryan RL, Liu S, Newman J, O’Brien JM, Considine J (1990) Squamous cell carcinoma arising in a chronic hydrocoele. Histopathology 17:178–180

    Article  CAS  PubMed  Google Scholar 

  10. Bushby LH, Miller FN, Rosairo S, Clarke JL, Sidhu PS (2002) Scrotal calcification: ultrasound appearances, distribution and aetiology. Br J Radiol 75:283–288

    Article  CAS  PubMed  Google Scholar 

  11. Culver GJ, Tannenhaus J (1960) Calcification of the vas deferens in diabetes. JAMA 173:648–651

    Article  CAS  Google Scholar 

  12. Cummings OW, Ulbright TM, Young RH, Del Tos AP, Fletcher CD, Hull MT (1997) Desmoplastic small round cell tumors of the paratesticular region. A report of six cases. Am J Surg Pathol 21:219–225

    Article  CAS  PubMed  Google Scholar 

  13. Davis JE (1992) Male sterilization. Curr Opin Obstet Gynecol 4:522–526

    CAS  PubMed  Google Scholar 

  14. Deane RE, May RE (1982) Absent vas deferens in association with renal abnormalities. Br J Urol 54:298–299

    Article  CAS  PubMed  Google Scholar 

  15. Dehner LP, Scott D, Stocker JT (1986) Meconium periorchitis: a clinicopathologic study of four cases with a review of the literature. Hum Pathol 17:807–812

    Article  CAS  PubMed  Google Scholar 

  16. Esslimani M, Serre I, Granier M, Robert M, Baldet P, Costes V (1999) Amylose urogénitale : étude anatomo-clinique à propos de 8 cas. Ann Pathol 19:487–491

    CAS  PubMed  Google Scholar 

  17. Evans K (2004) Rapidly growing adenomatoid tumor extending into testicular parenchyma mimics testicular carcinoma. Urology 64:589e12–589e13

    Article  Google Scholar 

  18. Flickinger CJ (1985) The effects of vasectomy on the testis. N Engl J Med 313:1283–1285

    Article  CAS  PubMed  Google Scholar 

  19. Ganem JP, Jhaveri FM, Marroum MC (1998) Primary adenocarcinoma of the epididymis: case report and review of the literature. Urology 52:904–908

    Article  CAS  PubMed  Google Scholar 

  20. Gilcrease MZ, Schmidt L, Zbar B, Truong L, Rutledge M, Wheeler TM (1995) Somatic von Hippel Lindau mutation in clear cell papillary cystadenoma of the epididymis. Hum Pathol 26:1341–1346

    Article  CAS  PubMed  Google Scholar 

  21. Glassy FJ, Mostofi FK (1956) Spermatic granulomas of the epididymis. Am J Clin Pathol 26:1303–1313

    CAS  PubMed  Google Scholar 

  22. Gupta AS, Kothari LK, Bapna RB (1975) Surgical sterilization by vasectomy and its effects on the structure and function of the testis in man. Br J Surg 62:59–63

    Article  CAS  PubMed  Google Scholar 

  23. Heath AL, Mann DW, Eckstein HB (1984) Epididymal abnormalities associated with maldescent of the testis. J Pediatr Surg 19:47–49

    Article  CAS  PubMed  Google Scholar 

  24. Hedinger C, Dhom G (1991) Pathologie des männlichen Genitales. In: Doerr W, Seifert G (Hrsg) Spezielle pathologische Anatomie, Bd. 21. Springer, Berlin

    Google Scholar 

  25. Hellema HW, Rumke P (1978) Sperm autoantibodies as a consequence of vasectomy. I. Within 1 year post-operation. Clin Exp Immunol 31:18–29

    PubMed Central  CAS  PubMed  Google Scholar 

  26. Hellema HW, Samuel T, Rumke P (1979) Sperm autoantibodies as a consequence of vasectomy. II. Long-term follow-up studies. Clin Exp Immunol 38:31–36

    PubMed Central  CAS  PubMed  Google Scholar 

  27. Hicks CM, Skoog SJ, Done S (1989) Ectopic vas deferens, imperforate anus and hypospadias: a new triad. J Urol 141:586–588

    CAS  PubMed  Google Scholar 

  28. Hirschowitz L, Rode J, Guillebaud J, Bounds W, Moss E (1988) Vasitis nodosa and associated clinical findings. J Clin Pathol 41:419–423

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  29. Hollowood K, Fletcher CD (1992) Pseudosarcomatous myofibroblastic proliferations of the spermatic cord (″proliferative funiculitis″). Histologic and immunohistochemical analysis of a distinctive entity. Am J Surg Pathol 16:448–454

    Article  CAS  PubMed  Google Scholar 

  30. Hoosen AA, O’Farrell N, van den Ende J (1993) Microbiology of acute epididymitis in a developing community. Genitourin Med 69:361–363

    PubMed Central  CAS  PubMed  Google Scholar 

  31. Hori S, Tsutsumi Y (1995) Histological differentiation between chlamydial and bacterial epididymitis: nondestructive and proliferative versus destructive and abscess forming – immunohistochemical and clinicopathological findings. Hum Pathol 26:402–407

    Article  CAS  PubMed  Google Scholar 

  32. Jarow JP, Budin RE, Dym M, Zirkin BR, Noren S, Marshall FF (1985) Quantitative pathologic changes in the human testis after vasectomy. A controlled study. N Engl J Med 313:1252–1256

    Article  CAS  PubMed  Google Scholar 

  33. Jones R (2004) Sperm survival versus degradation in the mammalian epididymis: A hypothesis. Biol Reprod 71:1405–1411

    Article  CAS  PubMed  Google Scholar 

  34. Joshi SA, Shaikh S, Ranpura S, Khole VV (2003) Postnatal development and testosterone dependence of a rat epididymal protein identified by neonatal tolerization. Reproduction 25:495–507

    Article  Google Scholar 

  35. Jun SY, Kim KR, Cho KS, Ro JY (2003) Localized amyloidosis of seminal vesicle and vas deferens: report of two cases. Korean Med Sci 18:447–451

    Article  Google Scholar 

  36. King ES (1951) Squamous epithelium in encysted hydrocele of the cord. A note on squamous epithelium of peritoneal origin. Aust N Z J Surg 20:265–271

    Article  CAS  PubMed  Google Scholar 

  37. Kirchhoff C (2002) The dog as a model to study human epididymal function at a molecular level. Mol Hum Reprod 8:695–701

    Article  CAS  PubMed  Google Scholar 

  38. Kiser GC, Fuchs EF, Kessler S (1986) The significance of vasitis nodosa. J Urol 136:42–44

    CAS  PubMed  Google Scholar 

  39. Krismann M, Muller KM, Jaworska M, Johnen G (2002) Molecular cytogenetic differences between histological subtypes of malignant mesotheliomas: DNA cytometry and comparative genomic hybridization of 90 cases. J Pathol 197:363–371

    Article  CAS  PubMed  Google Scholar 

  40. Kruse-Lösler B, Gaertner C, Bürger H, Seper L, Joos U, Kleinheinz J (2006) Melanotic neuroectodermal tumor of infancy: systematic review of the literature and presentation of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:204–216

    Article  PubMed  Google Scholar 

  41. Kuo T, Gomez LG (1981) Monstrous epithelial cells in human epididymis and seminal vesicles. A pseudomalignant change. Am J Surg Pathol 5:483–490

    Article  CAS  PubMed  Google Scholar 

  42. Lane TM, Wilde M, Schofield J, Trotter GA (1999) Benign cystic mesothelioma of the tunica vaginalis. BJU Int 84:533–534

    Article  CAS  PubMed  Google Scholar 

  43. Leung GP, Cheung KH, Leung CT, Tsang MW, Wong PY (2004) Regulation of epididymal principal cell functions by basal cells: role of transient receptor potential (Trp) proteins and cyclooxygenase-1 (COX-1). Mol Cell Endocrinol 216:5–13

    Article  CAS  PubMed  Google Scholar 

  44. Leuschner I, Newton WA Jr, Schmidt D, Sachs N, Asmar L, Hamoudi A, Harms D, Maurer HM (1993) Spindle cell variants of embryonal rhabdomyosarcoma in the paratesticular region. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 17:221–230

    Article  CAS  PubMed  Google Scholar 

  45. Lowenthal SB, Goldstein AM, Terry R (1981) Cholesterol granuloma of tunica vaginalis simulating testicular tumor. Urology 18:89–90

    Article  CAS  PubMed  Google Scholar 

  46. Martinez-Garcia F, Regadera J, Cobo P, Palacios J, Paniagua R, Nistal M (1995) The apical mitochondria-rich cells of the mammalian epididymis. Andrologia 27:195–206

    Article  CAS  PubMed  Google Scholar 

  47. McDonald SW (2000) Cellular responses to vasectomy. Int Rev Cytol 199:295–339

    Article  CAS  PubMed  Google Scholar 

  48. Mensi C, Pelagatta M, Siano C, Consonni D, Riboldi L, Bertazzi PA (2012) Mesothelioma of the tunica vaginalis testis and asbestos exposure. BJU Int 110:533–537

    Article  PubMed  Google Scholar 

  49. Merry C, Sweeney B, Puri P (1997) The vanishing testis: anatomical and histological findings. Eur Urol 31:65–67

    CAS  PubMed  Google Scholar 

  50. Middleton RG, Urry RL (1980) Vasovasostomy and semen quality. J Urol 123:518

    CAS  PubMed  Google Scholar 

  51. Mikuz G, Hopfel-Kreiner I (1982) Papillary mesothelioma of the tunica vaginalis propria testis. Case report and ultrastructural study. Virchows Arch A Pathol Anat Histol 396:231–238

    Article  CAS  PubMed  Google Scholar 

  52. Mikuz G, Schwarz C, Bartsch G (1985) Wert der semiquantitativen morphologischen Beurteilung von Hodenbiopsien bei Fertilitätsstörungen des Mannes. Pathologe 4:244–251

    Google Scholar 

  53. Murai Y (2001) Malignant mesothelioma in Japan:analysis of registred autopsy cases. Arch Environ Health 56:84–88

    Article  CAS  PubMed  Google Scholar 

  54. Nistal M, Garcia-Cabezas MA, Regadera J, Castillo MC (2004) Microlithiasis of the epididymis and the rete testis. Am J Surg Pathol 28:514–522

    Article  PubMed  Google Scholar 

  55. Nistal M, Gonzalez-Peramato P, Serrano A, Regadera J (2004) Xanthogranulomatous funiculitis and orchiepididymitis: report of 2 cases with immunohistochemical study and literature review. Arch Pathol Lab Med 128:911–914

    PubMed  Google Scholar 

  56. Nistal M, Santamaria L, Codesal J, Paniagua R (1989) Secondary amyloidosis of the testis: an electron microscopic and histochemical study. Appl Pathol 7:2–7

    CAS  PubMed  Google Scholar 

  57. Oben FT, Wright RD, Ahaghotu CA (2004) Tuberculous epididymitis with extensive retroperitoneal and mediastinal involvement. Urology 64:156–158

    Article  PubMed  Google Scholar 

  58. Oertel YC, Johnson FB (1977) Sclerosing lipogranuloma of the male genitale. Review of 23 cases. Arch Path Lab Med 101:321–326

    CAS  PubMed  Google Scholar 

  59. Osegbe DN (1991) Testicular function after unilateral bacterial epididymo-orchitis. Eur Urol 19:204–208

    CAS  PubMed  Google Scholar 

  60. Pelzer A, Akkad T, Herwig R, Rogatsch H, Pinggera GM, Bartsch G, Rehder P (2004) Synchronous bilateral malignant mesothelioma of tunica vaginalis testis: early diagnosis. Urology 64:1031e18–1031e19

    Article  Google Scholar 

  61. Perez-Ordonez B, Srigley JR (2000) Mesothelial lesions of the paratesticular region. Semin Diagn Pathol 17:294–306

    CAS  PubMed  Google Scholar 

  62. Plas E, Riedl CR, Pfluger H (1998) Malignant mesothelioma of the tunica vaginalis testis: review of the literature and assessment of prognostic parameters. Cancer 83:2437–2446

    Article  CAS  PubMed  Google Scholar 

  63. Pozza D, Masci P, Amodeo S, Marchionni L (1994) Papillary cystadenoma of the epididymis as a cause of obstructive azoospermia. Urol Int 53:222–224

    Article  CAS  PubMed  Google Scholar 

  64. Rowland RD, Nicholson GW (1929) A case of primary squamous celled epithelioma of the epididymis. Lancet 1:304–306

    Google Scholar 

  65. Sadek I, Biron P, Kus T (1993) Amiodarone-induced epididymitis: report of a new case and literature review of 12 cases. Can J Cardiol 9:833–836

    CAS  PubMed  Google Scholar 

  66. Sakaki M, Hirokawa M, Horiguchi H, Wakatsuki S, Sano T (2000) Vasitis nodosa: immunohistochemical findings – case report. APMIS 108:283–286

    Article  CAS  PubMed  Google Scholar 

  67. Sawyer JR, Tryka AF, Lewis JM (1992) A novel reciprocal chromosome translocation t(11;12)(p13;q12) in an intrabdominal desmoplastic small round-cell tumor. Am J Surg Pathol 16:411–416

    Article  CAS  PubMed  Google Scholar 

  68. Seethala RR, Tirkes AT, Weinstein S, Tomaszewski JE, Malkowicz SB, Genega EM (2003) Diffuse fibrous pseudotumor of the testicular tunics associated with an inflamed hydrocele. Arch Pathol Lab Med 127:742–744

    PubMed  Google Scholar 

  69. Shimada S, Ono K, Suzuki Y, Mori N (2004) Malignant mesothelioma of the tunica vaginalis testis: a case with a predominant sarcomatous component. Pathol Int 54:930–934

    Article  PubMed  Google Scholar 

  70. Shned AR, Selikowitz SM (1986) Epididymitis nodosa. An epididymal lesion analogous to vasitis nodosa. Arch Pathol Lab Med 110:61–64

    Google Scholar 

  71. Somekh E, Gorenstein A, Serour F (2004) Acute epididymitis in boys: evidence of a postinfectous etiology. J Urol 171:391–394

    Article  PubMed  Google Scholar 

  72. Stephenson TJ, Mills PM (1986) Adenomatoid tumours: an immunohistochemical and ultrastructural appraisal of their histogenesis. J Pathol 148:327–335

    Article  CAS  PubMed  Google Scholar 

  73. Sutovsky P, Moreno R, Ramalho-Santos J, Dominko T, Thompson WE, Schatten G (2001) A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis. J Cell Sci 114:1665–1675

    CAS  PubMed  Google Scholar 

  74. Svec A, Mikyskova I, Hes O, Tachezy R (2003) Human papillomavirus infection of the epididymis and ductus deferens: an evaluation by nested polymerase chain reaction. Arch Pathol Lab Med 127:1471–1474

    PubMed  Google Scholar 

  75. Tsuno MM, Gerber JM, Pokras RS (1991) Calcification of vas deferens associated with diabetes mellitus. J Manipulative Physiol Ther 14:70–73

    CAS  PubMed  Google Scholar 

  76. Vohra S, Morgentaler A (1997) Congenital anomalies of the vas deferens, epididymis, and seminal vesicles. Urology 49:313–321

    Article  CAS  PubMed  Google Scholar 

  77. Wernert N, Goebbels R, Prediger L (1986) Papillary cystadenoma of the epididymis. Case report and review of the literature. Pathol Res Pract 181:260–264

    Article  CAS  PubMed  Google Scholar 

  78. Whitehead, Leiter E (1981) Genital abnormalities and abnormal semen analyses in male patients exposed to diethylstilbestrol in utero. J Urol 125:47–50

    CAS  PubMed  Google Scholar 

  79. Witkin SS, Jeremias J, Bongiovanni AM, Munoz MG (1996) Immune regulation in the male genital tract. Infect Dis Obstet Gynecol 4:131–135

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  80. Wollin M, Marshall FF, Fink MP, Malhotra R, Diamond DA (1987) Aberrant epididymal tissue: a significant clinical entity. J Urol 138:1247–1250

    CAS  PubMed  Google Scholar 

  81. Wong PY (1998) CFTR gene and male fertility. Mol Hum Reprod 4:107–110

    Article  CAS  PubMed  Google Scholar 

  82. Woodward PJ, Schwab CM, Sesterhenn IA (2003) From the archives of the AFIP: extratesticular scrotal masses: radiologic-pathologic correlation. Radiographics 23:215–240

    Article  PubMed  Google Scholar 

  83. www.ImmunoQuery.com

  84. Yeung CH, Nashan D, Sorg C, Oberpenning F, Schulze H, Nieschlag E, Cooper TG (1994) Basal cells of the human epididymis – antigenic and ultrastructural similarities to tissue-fixed macrophages. Biol Reprod 50:917–926

    Article  CAS  PubMed  Google Scholar 

  85. Zdrodowska-Stefanow B, Ostaszewska I, Darewicz B, Darewicz J, Badyda J, Pucilo K, Bulhak V, Szczurzewski M (2000) Role of Chlamydia trachomatis in epididymitis. Part I: Direct and serologic diagnosis. Med Sci Monit 6:1113–1118

    CAS  PubMed  Google Scholar 

  86. Zimmerman KG, Johnson PC, Paplanus SH (1983) Nerve invasion by benign proliferating ductules in vasitis nodosa. Cancer 51:2066–2069

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Klinisches Institut für Pathologie, Medizinische Universität Wien, Währinger Gürtel 18–20, 1090, Wien, Österreich

    Peter Mazal Prof. Dr.

  2. Institut für Pathologie, Med. Universität, Müllerstr.44, 6020, Innsbruck, Österreich

    Gregor Mikuz Prof. em. Dr.

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  1. Gregor Mikuz Prof. em. Dr.
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  2. Peter Mazal Prof. Dr.
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Correspondence to Gregor Mikuz Prof. em. Dr. .

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Editors and Affiliations

  1. Abt. Nephropathologie, Pathologisches Institut Universität Erlangen-Nürnberg, Erlangen, Germany

    Kerstin Amann

  2. Klinisches Institut für Pathologie, Medizinische Universität Wien Allg. Krankenhaus der Stadt Wien, Wien, Austria

    Renate Kain

  3. Konsultationszentrum für Pankreas- und Endokrine Tumoren, Institut für Pathologie, Ismaninger Str. 22, 81675, Technische Universität München Klinikum rechts der Isar, München, Germany

    Günter Klöppel

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Mikuz, G., Mazal, P. (2016). Nebenhoden, Hodenhüllen und Samenstrang. In: Amann, K., Kain, R., Klöppel, G. (eds) Pathologie. Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04566-0_2

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