Abstract
Thin and flexible probes made with hollow-optical fibers may be useful for remote spectroscopy. Experimental results showed that these probes are useful for endoscopic measurements of infrared and Raman spectroscopy. A hollow-fiber probe has been used for remote FT-IR spectroscopy in the form of endoscopic measurement of infrared reflectometry spectra inside the body. This measurement was made possible by the hollow-fiber probe’s flexibility, durability, nontoxicity, and low transmission loss. A hollow-fiber probe with a ball lens at the end works as a confocal system for Raman spectroscopy. It can thus detect the molecular structure of biotissues with a high signal-to-noise ratio. Owing to their small diameter, the probes are useful for in vivo, noninvasive analysis using a flexible endoscope.
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Abbreviations
- ATR:
-
Attenuated total reflection
- COP:
-
Cyclic olefin polymer
- FT-IR:
-
Fourier transform infrared spectroscopy
- NA:
-
Numerical aperture
- TE mode:
-
Transverse electric mode
- d :
-
Thickness of dielectric layer
- j :
-
Imaginary unit
- k :
-
Extinction coefficient
- k 0 :
-
Wavenumber in vacuum
- n :
-
Refractive index
- p 0 :
-
Far-field profile of the incident beam
- R :
-
Power reflection coefficient
- r :
-
Reflection coefficient
- T :
-
Inner radius of circular hollow waveguide
- α :
-
Half of the power attenuation constant
- φ :
-
Phase factor of reflection coefficient
- ϕ :
-
Angle of incidence
- λ:
-
Wavelength
- θ :
-
Angle of incidence
- ρ :
-
Amplitude factor of reflection coefficient
- σ :
-
Root–mean-square height of irregular surface
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Matsuura, Y. (2010). Hollow-Optical Fiber Probes for Biomedical Spectroscopy. In: Zourob, M., Lakhtakia, A. (eds) Optical Guided-wave Chemical and Biosensors II. Springer Series on Chemical Sensors and Biosensors, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02827-4_7
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DOI: https://doi.org/10.1007/978-3-642-02827-4_7
Publisher Name: Springer, Berlin, Heidelberg
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