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Estrogen Signaling in the Regulation of Female Reproductive Functions

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Fertility Control

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 198))

Abstract

Estrogens influence fertility and infertility in animals. This chapter reviews the use of estrogen as a contraceptive through the regulation of its production and action. It is concluded that the use of specific agonists and antagonists of estrogen action that avoid the global and unwanted side effects of estrogen offers new potential methods of contraception.

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Acknowledgments

Support from the National Health & Medical Research Council of Australia (RegKeys #241000, #441101 and #550900) and Division of Intramural Research of the NIEHS/NIH to KSK.

Author information

Authors and Affiliations

  1. Prince Henry’s Institute of Medical Research, 5152, Clayton, VIC, 3168, Australia

    J. K. Findlay, S. H. Liew & E. R. Simpson

  2. Laboratory of Reproductive and Developmental Toxicology, NIEHS/NIH, Room 12233, Research Triangle Park, Durham, NC, 27709, USA

    K. S. Korach

Authors
  1. J. K. Findlay
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  2. S. H. Liew
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  3. E. R. Simpson
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  4. K. S. Korach
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Corresponding author

Correspondence to J. K. Findlay .

Editor information

Editors and Affiliations

  1. , Women's Health Care Research, Bayer Schering Pharma AG, Berlin, 13342, Berlin, Germany

    Ursula-F. Habenicht

  2. ARC Centre of Excellence in, Biotechnology & Development, University of Newcastle, Callaghan, 2308, New South Wales, Australia

    R. John Aitken

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Findlay, J.K., Liew, S.H., Simpson, E.R., Korach, K.S. (2010). Estrogen Signaling in the Regulation of Female Reproductive Functions. In: Habenicht, UF., Aitken, R. (eds) Fertility Control. Handbook of Experimental Pharmacology, vol 198. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02062-9_2

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