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Thromboembolische Erkrankungen bei Neugeborenen und Kindern

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Hämostaseologie

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Zusammenfassung

Venöse Thrombosen sind seltene Erkrankungen im Kindesalter (0,07–0,14:10.000 Kinder), in den letzten Jahren werden sie jedoch zunehmend diagnostiziert. Betroffen sind überwiegend Neugeborene und Säuglinge. In den meisten Fällen treten sie sekundär im Rahmen von schweren Grunderkrankungen auf. Neben externen Triggern (wie z. B. zentralvenösen Kathetern) und erworbenen thrombophilen Risikofaktoren (wie z. B. Antiphospholipidantikörpern) werden angeborene thrombophile Risikofaktoren wie Antithrombin-, Protein-C- und Protein-S-Mangel, die Mutationen im Faktor-V-Gen oder im Prothrombingen und erhöhtes Lipoprotein a als zusätzliche Risikofaktoren angesehen.

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Authors and Affiliations

  1. Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik, Albert-Schweitzer-Straße 33, D-48149, Münster

    Prof. Dr. U. Nowak-Göttl

  2. Kinderklinik und Kinderpoliklinik, Dr. von Haunersches Kinderspital, Pädiatrisches Hämophiliezentrum, Klinikum der Universitätsklinik München, Lindwurmstraße 4, D-80337, München

    Dr. C. Bidlingmaier

  3. Kinderklinik und Kinderpoliklinik, Dr. von Haunersches Kinderspital, Pädiatrische Hämostaseologie/Pädiatrisches Hämophiliezentrum, Klinikum der Universitätsklinik München, Lindwurmstraße 4, D-80337, München

    Priv.-Doz. Dr. K. Kurnik

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  1. Prof. Dr. U. Nowak-Göttl
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  2. Dr. C. Bidlingmaier
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  3. Priv.-Doz. Dr. K. Kurnik
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  1. Institut für Experimentelle Hämatologie und Transfusionsmedizin, Universitätsklinikum Bonn, Sigmund-Freud-Straße 25, 53105, Bonn

    Bernd Pötzsch

  2. Kerckhoff Klinik, BenekeStraße 2-8, 61231, Bad Nauheim

    Katharina Madlener

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Nowak-Göttl, U., Bidlingmaier, C., Kurnik, K. (2010). Thromboembolische Erkrankungen bei Neugeborenen und Kindern. In: Pötzsch, B., Madlener, K. (eds) Hämostaseologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01544-1_37

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  • DOI: https://doi.org/10.1007/978-3-642-01544-1_37

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