Abstract
The term “pineal area” refers either to the pineal gland, which is situated in the deep part of the brain, or to the pineal region, which includes the gland itself and its surrounding structures. Pineal tumors represent 3–8% of intracranial tumors in children and 0.4–1% of brain tumors in adults [1]. In Asia the pineal tumors are most often found among the pediatric population where the incidence is about 10–12.5% [2].
Although CT and MRI characteristics of pineal tumors are nonspecific, the localization of a tumor in the pineal region allows one to choose the most appropriate therapeutic method. In this chapter we will deal with the germ cell and the pineal cell tumors, which represent the vast majority of the pineal gland tumors.
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References
Tien RD, Barkovich AJ, Edwards MSB (1990) MR imaging of pineal tumors. AJNR 11:557–565
Koide O, Watanabe Y, Sato K (1980) Pathological survey of intracranial germinoma and pinealoma in Japan. Cancer 45:2119–2130
Truex RC, Carpenter MB (1969) Human neuroanatomy. Williams & Wilkins, Baltimore
Osborne AG (1994) Diagnostic neuroradiology. Mosby-Year Book, St. Louis
Kirkwood JR (1990) Essential of neuroimaging. Churchill Livingstone, New York
Jennings MT, Gelman R, Hochberg F (1985) Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 63:155–167
Zimmerman RA, Bilanluk LT, Wood JH, Bruce DA, Schut L (1980) Computed tomography of pineal, parapineal, and histologically related tumors. Radiology 137:669–677
Hoffman HJ, Otsubo H (1991) Intracranial gem-cell tumors. J Neurosurg 74:545–551
Soejima T, Takeshita I (1987) Computed tomography of germinomas in basal ganglia and thalamus. Neuroradiology 29:366–370
Luh GY, Bird CG (1999) Imaging of brain tumors in the pediatric population. Radiol Clin N Am 9(4):691–716
Maity A, Shu HK, Janss A et al (2004) Craniospinal radiation in the treatment of biopsy proven intracranial germinomas: twenty-five years’ experience in a single center. Int J Radiat Oncol Biol Phys 58:1165–1170
Friedman NB (1947) Germinoma of the pineal. Its identity with germinoma (“seminoma”) of the testis. Cancer Res 7:363–368
Sung DMD, Harisiadis L, Chang Ch MD (1978) Midline pineal tumors and suprasellar germinomas: highly curable by irradiation. Radiology 128:745–751
Smirniotopoulos JG, Rushing EJ, Mena H (1992) Pineal region masses: differential diagnosis. Radiographics 12:577–596
Prahlow JA, Challa VR (1996) Neoplasms of the pineal region. South Med J 89:1081–1087
Zee CS, Segal H, Apuzzo M et al (1991) MR imaging of pineal region neoplasms. J Comput Assist Tomogr 15:56–63
Plassche McCormack TJ, Jr WM, Lin SR (1978) Ruptured teratoid tumor in the pineal region. J Comput Assist Tomogr 2:499–501
Chang T, Teng MMH, Guo WY, Sheng WC (1989) CT of pineal tumors and intracranial germ-cell tumors. AJNR 10:1039–1044
Arita NMD, Bitoh Sh MD (1980) Primary pineal endodermal sinus tumor with elevated serum and CSF alphafetoprotein levels. J Neurosurg 53:244–248
Hoffman HJ, Otsubo H, Hendrick EB et al (1991) Intracranial germ cell tumors in children. J Neurosurg 74:545–551
Raaijmakers C, Wilms G, Demaerel P, Bart AL (1992) Pineal teratocarcinoma with drop metastases: MR features. Neuroradiol 34:227–229
Herrick MK (1984) Pathology of pineal tumors. In: Neuwalt EA (ed) Diagnosis and treatment of pineal region tumors. Williams & Wilkins, Baltimore, pp 31–60
Chang CGS, Kageyama N (1981) Pineal tumors: clinical diagnosis, with special emphasis on the significance of pineal calcification. Neurosurgery 8:656–668
Schild RM, Scheithauer BW, Schomberg PJ et al (1993) Pineal parenchymal tumors. Cancer 72:870–880
Kumar P, Tatke M, Sharma A, Singh D (2006) Histological analysis of lesions of the pineal region: a retrospective study of 12 years. Pathol Res Pract 202:85–92
Nakagawa H, Iwasaki S, Kichikawa K et al (1990) MR imaging of pineocytoma: report of two cases. AJNR 11:195–198
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (2007) WHO classification of tumours of the central nervous system. IARC, Lyon, pp 122–127
Ganti SR, Hilal SK (1986) CT of pineal region tumors. AJR 146:451–458
Silvera VM (2008) Pineal region tumors. In: Newton HB, Jolesz FA (eds) Handbook of neuro-oncology neuroimaging. Academic, USA, pp 449–459
Pustaszeri M, Pica A, Janzer R (2006) Pineal parenchymal tumors of intermediate differentiation in adults: case report and literature review. Neuropathology 26:153–157
Sasaki A, Horiguchi K, Nakazato Y (2006) Pineal parenchymal tumor of intermediate differentiation with cytologic pleomorphism. Neuropathology 26:212–217
Provenzale JM, Weber AL, Kinworth JK et al (1995) Radiologic-pathologic correlation: Bilateral retinoblastoma with coexistent pineoblastoma (trilateral retinoblastoma). AJNR 16:157–165
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Drevelegas, A., Strigaris, A.K., Samara, C.H. (2011). Pineal Tumors. In: Drevelegas, A. (eds) Imaging of Brain Tumors with Histological Correlations. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87650-2_7
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DOI: https://doi.org/10.1007/978-3-540-87650-2_7
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