Skip to main content

Deacetylcephalosporin-C acetyltransferase

  • Chapter
Class 2 Transferases

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume S2))

  • 561 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Martin, J.F.; Gutierrez, S.; Fernandez, F.J.; Velasco, J.; Fierro, F.; Marcos, A.T.; Kosalkova, K.: Expression of genes and processing of enzymes for the biosynthesis of penicillins and cephalosporins. Antonie Leeuwenhoek, 65, 227–243 (1994)

    Article  CAS  PubMed  Google Scholar 

  2. Gutierrez, S.; Velasco, J.; Marcos, A.T.; Fernandez, F.J.; Fierro, F.; Barredo, J.L.; Diez, B.; Martin, J.F.: Expression of the cefG gene is limiting for cephalosporin biosynthesis in Acremonium chrysogenum. Appl. Microbiol. Biotechnol., 48, 606–614 (1997)

    Article  CAS  PubMed  Google Scholar 

  3. Matsuda, A.; Sugiura, H.; Matsuyama, K.; Matsumoto, H.; Ichikawa, S.; Komatsu, K.: Molecular cloning of acetyl coenzyme A: deacetylcephalosporin C O-acetyltransferase cDNA from Acremonium chrysogenum: sequence and expression of catalytic activity in yeast. Biochem. Biophys. Res. Commun., 182, 995–1001 (1992)

    Article  CAS  PubMed  Google Scholar 

  4. Matsuda, A.; Sugiura, H.; Matsuyama, K.; Matsumoto, H.; Ichikawa, S.; Komatsu, K.: Cloning and disruption of the cefG gene encoding acetyl coenzyme A: deacetylcephalosporin C O-acetyltransferase from Acremonium chrysogenum. Biochem. Biophys. Res. Commun., 186, 40–46 (1992)

    Article  CAS  PubMed  Google Scholar 

  5. Velasco, J.; Gutierrez, S.; Campoy, S.; Martin, J.F.: Molecular characterization of the Acremonium chrysogenum cefG gene product: the native deacetylcephalosporin C acetyltransferase is not processed into subunits. Biochem. J., 337 (Pt 3), 379–385 (1999)

    Article  CAS  PubMed  Google Scholar 

  6. Matsuyama, K.; Matsumoto, H.; Matsuda, A.; Sugiura, H.; Komatsu, K.; Ichikawa, S.: Purification of acetyl coenzyme A: deacetylacephalosporin C Oacetyltransferase from Acremonium chrysogenum. Biosci. Biotechnol. Biochem., 56, 1410–1412 (1992)

    Article  CAS  PubMed  Google Scholar 

  7. Mathison, L.; Soliday, C.; Stepan, T.; Aldrich, T.; Rambosek, J.: Cloning, characterization, and use in strain improvement of the Cephalosporium acremonium gene cefG encoding acetyl transferase. Curr. Genet., 23, 33–41 (1993)

    Article  CAS  PubMed  Google Scholar 

  8. Gutierrez, S.; Velasco, J.; Fernandez, F.J.; Martin, J.F.: The cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine Oacetyltransferase. J. Bacteriol., 174, 3056–3064 (1992)

    CAS  PubMed  Google Scholar 

  9. Scheidegger, A.; Gutzwiller, A.; Kuenzi, M.T.; Fiechter, A.; Nuesch, J.: Investigation of acetyl-CoA:deacetylcephalosporin C O-acetyltransferase of Cephalosporium acremonium. J. Biotechnol., 3, 109–117 (1985)

    Article  CAS  Google Scholar 

  10. Ullan, R.V.; Campoy, S.; Casqueiro, J.; Fernandez, F.J.; Martin, J.F.: Deacetylcephalosporin C production in Penicillium chrysogenum by expression of the isopenicillin N epimerization, ring expansion, and acetylation genes. Chem. Biol., 14, 329–339 (2007)

    Article  CAS  PubMed  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2009). Deacetylcephalosporin-C acetyltransferase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 Transferases. Springer Handbook of Enzymes, vol S2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85697-9_17

Download citation

Publish with us

Policies and ethics