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Evaluation of Malignant Bone Disease Using DW-MRI

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Diffusion-Weighted MR Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Summary

The bones are frequently involved as a site of meta-static disease in patients with cancer. Accurate determination of the presence, location and extent of bone involvement is of therapeutic and prognostic importance. Diffusion-weighted MR imaging performed regionally or as whole-body imaging has been shown to have a high diagnostic accuracy for the identification of bone metastases when combined with conventional MR imaging. Both qualitative and quantitative DW-MRI have also been found to be of value for distinguishing between benign and malignant causes of vertebral fractures. There is also promise in the application of quantitative ADC for evaluating treatment response of malignant bone diseases, as current imaging criteria are inadequate in assessing treatment changes of bone lesions to therapy.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Nakamichi, Higashinari-Ku, Osaka, 537-8511, Japan

    K. Nakanishi

  2. Department of Diagnostic and Interventional Radiology, Kantonsspital Winterthur, Brauerstrasse 15, Postfach 834, Winterthur, CH-8401, Switzerland

    A. Gutzeit

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  1. K. Nakanishi
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  2. A. Gutzeit
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Editors and Affiliations

  1. Royal Marsden NHS Foundation Trust, Department of Radiology, Downs Road, Sutton, SM2 5PT, United Kingdom

    D. M. Koh

  2. Department of Diagnostic, Interventional and Paediatric Radiology, Universitätsspital Bern Inselspital, Freiburgstr. 10, Bern, 3010, Switzerland

    H. C. Thoeny

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Nakanishi, K., Gutzeit, A. (2010). Evaluation of Malignant Bone Disease Using DW-MRI. In: Koh, D.M., Thoeny, H.C. (eds) Diffusion-Weighted MR Imaging. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-78576-7_13

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  • DOI: https://doi.org/10.1007/978-3-540-78576-7_13

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