Abstract
This chapter provides an introduction to the field of biocompatibility of dental materials, including definition of terms, clinical symptoms and basic principles in biocompatibility; e.g. the dose-effect relation principle and the risk concept. In recent years, the importance of the biocompatibility of dental materials as an independent discipline of dental materials science has been recognized. Consequently, a number of terms and principles have been developed or were adopted from toxicology. Some of these terms may seem familiar to patients and dentists alike; for example the term ‘safety’. Their exact definition within the framework of biocompatibility is, however, not always well understood. To avoid misunderstandings and to allow discussions between dentists, manufacturers and patients at an objective and scientific level, a certain knowledge of some fundamental terms and aspects of biocompatibility is necessary.
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References
Amdur, M. O., Doull. J., Klaasen, C. D. (eds): Casarett and Doull’s Toxicology: The Basic Science of Poison. McGraw-Hill, New York 1996.
Bundesverband der Pharmazeutischen Industrie e.V. Arzneimittel: Chancen und Risiken. [Chances and Risks] Pharma, Frankfurt 1985.
Christ, O.P.: ISO/IEC 14971 soll Harmonisierte Europäische Norm werden. [ISO/IEC 14871 shall become a Harmonized European Standard] Medizinprodukte Journal, 7, 7–8 (2000).
Friedl, K.-H., Schmalz, G., Hiller, K.-A.: Flüssigkeitskulturen zur Prüfung der Wirkung zahnärztlicher Werkstoffe auf das Bakterienwachstum. [Liquid cultures for testing the antibacterial effect of dental materials] Dtsch Zahnärztl Z 47, 826–831 (1992).
Garhammer, P., Schmalz, G., Hiller, K.-A., Reitinger, T., Stolz, W.: Patients with local adverse effects from dental alloys: frequency, complaints, symptoms, allergy. Clin Oral Investig 5, 240–249 (2001).
Gottwald, B., Kupfer, J., Traenckner, I., Ganss, C., Gieler, U.: Psychological, allergic, and toxicological aspects of patients with amalgam-related complaints. Psychother Psychosom 71, 223–232 (2002).
Hansel, C., Leyhausen, G., Mai, U.E., Geurtsen, W.: Effects of various resin composite (co)monomers and extracts caries-associated micro-organisms in vitro. J Dent Res 77, 60–67 (1998).
International Electrotechnical Commission: IEC 60601-1-4, Medical electrical equipment. Part 1: general requirements for safety. 4. Collateral standard: programmable electrical medical systems. International Electrotechnical Commission, Geneva 1996.
International Organization for Standardization: ISO 10993-1: Biological evaluation of medical devices. Part 1: evaluation and testing. International Organization for Standardization, Geneva 1992.
International Organization for Standardization: ISO 14971: Medical devices – application of risk analysis to medical devices. International Organization for Standardization, Geneva 2000.
International Organization for Standardization: ISO 10993-17: Biological evaluation of medical devices. Part 17: establishment of allowable limits for leachable substances. International Organization for Standardization, Geneva 2002.
Kallus, T., Mjör, I.A.: Incidence of adverse effects of dental materials. Scand J Dent Res 99, 236–240 (1991).
Kayser, D., Schlede, E. (eds): Chemikalien und Kontaktallergien. [Chemicals and contact allergies] Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin. Urban & Vogel, München 2001.
van Leeuwen, C.J., Hermens, J.L.M.: Risk Assessment of Chemicals. An Introduction. Kluwer Academic, Dordrecht 1995.
Levinson, W., Jawath, E.: Medical Microbiology & Immunology. Prentice Hall International, London 1996.
Marquardt, H., Schäfer, S. G. (eds): Lehrbuch der Toxikologie. [Textbook on Toxicology] Spektrum Akad., Heidelberg 1997.
Nordberg, M., Duffus, J., Templeton, D.M.: Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003). Pure Appl Chem 76, 1033–1082 (2004).
Orton, D.I., Wilkinson, J.D.: Cosmetic allergy: incidence, diagnosis, and management. Am J Clin Dermatol 5, 327–337 (2004).
Schmalz, G.: Der Einfluß verschiedener Frontzahnfüllungsmaterialien auf das In-vitro-Wachstum von Streptococcus mutans. [The effect of various front tooth filling materials on the in vitro growth of Streptococcus mutans] Dtsch Zahnärztl Z 32, 575–579 (1977).
Schmalz, G., Garhammer, P.: Biological interactions of dental cast alloys with oral tissues. Dent Mater 18, 396–406 (2002).
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Schmalz, G., Arenholt-Bindslev, D. (2009). Basic Aspects. In: Biocompatibility of Dental Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77782-3_1
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DOI: https://doi.org/10.1007/978-3-540-77782-3_1
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