Abstract
This paper presents a formal approach to the study of evolution of biological pathways. The basic idea is to use the Beta Workbench to model and simulate pathway in connection with evolutionary algorithms to implement mutations. A fitness function is used to select individuals at any generation. The feasibility of the approach is demonstrated with a simple example.
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Dematté, L., Priami, C., Romanel, A., Soyer, O. (2007). A Formal and Integrated Framework to Simulate Evolution of Biological Pathways. In: Calder, M., Gilmore, S. (eds) Computational Methods in Systems Biology. CMSB 2007. Lecture Notes in Computer Science(), vol 4695. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75140-3_8
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DOI: https://doi.org/10.1007/978-3-540-75140-3_8
Publisher Name: Springer, Berlin, Heidelberg
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