Intelligent Approach to Cordblood Collection

Abstract

In the past, following the birth of a baby, the umbilical cord is usually discarded along with the placenta. It is now known that blood retrieved from the umbilical cord, commonly known as umbilical cord blood (UCB), is an increasingly important rich source of stem cells (Cairo and Wagner, 1997). These cells obtained from UCB can produce all other blood cells, including blood-clotting platelets, and red and white blood cells. In a way, UCB is similar in primary functions to donated bone marrow. The cells that are harvested from UCB or bone marrow can be used for the treatment of over 45 malignant and non-malignant diseases, including certain cancers such as leukemia, and immune and genetic disorders. UCB provides a readily available source of stem cells for transplantation in many situations where bone marrow is now used. More critically, there are many advantages to use UCB instead of other sources of stem cells such as bone marrow and peripheral blood:

• There is no risk involved in collection of UCB.

• UCB is much easier to collect and harvest without the risks of general anesthesia required to harvest bone marrow.

• UCB is readily available when needed if it is properly collected and stored at birth.

• UCB is often more compatible when used in transplants.

• UCB has lower procurement costs.

• UCB has demonstrated broader potential clinical applications for improving neural repair and bone and tissue growth.