Abstract
To better understand the human pulmonary system and governing aerosol deposition mechanisms within the lung, an accurate description of the airflow in the conductive and respiratory pulmonary airways is considered to be essential. In-vivo measurements are deemed impossible due to the small scales in the lung structure. Though numerical simulations can improve the insight, validation of the results is mostly lacking, especially in the extraction of particle trajectories. Numerical and experimental studies have been performed at the von Karman Institute for Fluid Dynamics on single and multiple bifurcation models representing simplifications of the lung system. Both steady and oscillating flows have been studied for the upper lung airways, while steady flow conditions were imposed in the modeling of the alveolar zones. Further experiments consisted in the extraction of particle trajectories in the models of the respiratory airways. This chapter presents an overview of the conducted measurement campaigns complemented with the main observations and results.
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References
E. R. Weibel: Morphometry of the Human Lung (Springer, Berlin, Heidelberg 1963)
R. F. Phalen, H. C. Yeh, G. M. Schum, O. G. Raabe: Application of an idealised model to morphometry of the mammalian tracheobranchial tree, Anat. Rec. 190, 167–176 (1978)
P. Corieri: Experimental and numerical investigation of flows in bifurcations within lung airways, Ph.D. thesis, von Karman Institute for Fluid Dynamics, Université Libre de Bruxelles and Rheinisch-Westfälische Technische Hochschule Aachen (1994)
H.-J. Pfeifer: Fundamentals of signal processing, in Laser Velocimetry, von Karman Institute Lecture Series (von Karman Institute 1991)
A. Ramuzat: Experimental investigation of flows within 2D bifurcations, {VKI} project report, von Karman Institute for Fluid Dynamics (1996)
F. Wilquem: A {2D} multiblock approach to solve viscous flows in lung bifurcations, {VKI} project report, von Karman Institute for Fluid Dynamics (1993)
J. Hammersley, D. Olson: Physical models for the smaller pulmonary airways, J. Appl. Physiol. 72, 2402–2414 (1992)
A. Ramuzat, M. L. Riethmuller, L. Angelucci: Particle image velocimetry using {B}ragg cell as optical shutter, in Proc. 17th Int. Congress on Instrumentation in Aerospace Simulation Facilities (ICIASF) (1997)
J. B. Moens: Development of a new D-PIV technique to investigate the flow behind a bluff body, {VKI} project report, von Karman Institute for Fluid Dynamics (1995)
F. Wilquem, G. Degrez: Numerical modelling of steady inspiratory airflow through a three-generation model of the human central airways, J. Biomech. Eng. 119, 52–65 (1997)
A. Ramuzat, S. Day, M. L. Riethmuller: Steady and unsteady {LDV} and {PIV} investigations of flow within {2D} lung bifurcations model, in Proc. 9th Int. Symposium Applications of Laser Techniques to Fluid Mechanics (1998)
A. Ramuzat, H. Richard, M. L. Riethmuller: {PIV} investigation of unsteady flows within lung bifurcations, in Proc. 8th Int. Conf. Laser Anemometry, Advances and Applications (1999)
F. Scarano, M. L. Riethmuller: Iterative multigrid application in {PIV} image processing, Exp. Fluids 26, 513–523 (1999)
F. R. Haselton, P. W. Scherer: Flow visualization of steady streaming in oscillatory flow through a bifurcating tube, J. Fluid Mech. 123, 315–333 (1982)
T. J. Pedley: Pulmonary fluid dynamics, Ann. Rev. Fluid Mech. 9, 229–274 (1977)
C. Raick, A. Ramuzat, P. Corieri, M. L. Riethmuller: Numerical and experimental study of spatial periodicity of steady air flows in pulmonary bifurcations, in Proc. 7th Triennal Int. Symposium Fluid Control Measurement and Visualization (2003)
A. Ramuzat, M. L. Riethmuller: {PIV} investigation of oscillating flows within a {3D} lung multiple bifurcations model, in Proc. 11th Int. Symposium on Application of Laser Techniques to Fluid Mechanics (2002)
R. Theunissen: Experimental investigation of aerosol deposition in lung airways, {VKI} project report, von Karman Institute for Fluid Dynamics (2004)
R. Theunissen, N. Buchmann, P. Corieri, M. L. Riethmuller, C. Darquenne: Experimental investigation of aerosol deposition in alveolar lung airways, in Proc. 13th Int. Symposium on Applications of Laser Techniques to Fluid Mechanics (2006)
S. T. Wereley, L. Gui, C. D. Meinhart: Advanced algorithms for microscale particle image velocimetry, AIAA J. 40, 1047–1055 (2002)
N. Buchmann: Experimental modeling of aerosol particles within lung bifurcations, {VKI} stagaire report, von Karman Institute for Fluid Dynamics (2005)
C. van Ertbruggen, N. Buchmann, R. Theunissen, P. Corieri, M. L. Riethmuller, C. Darquenne: Flow in a {3D} alveolated bend: {Validation} of {CFD} predictions with experimental results, in 5th World Congress of Biomechanics (2005)
C. Darquenne: Numerical and experimental investigation of aerosol transport and deposition in the human lung, Ph.D. thesis, Université Libre de Bruxelles and von Karman Institute for Fluid Dynamics (1995)
L. Harrington, K. G. Prisk, C. Darquenne: Importance of the bifurcation zone and branch orientation in simulated aerosol deposition in the alveolar zone of the human lung, J. Aerosol Sci. 37, 37–62 (2006)
M. Bilka: Experimental investigation of 3D Aerosol Motion within an alveolated duct, {VKI} project report, von Karman Institute for Fluid Dynamics (2006)
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Theunissen, R., Riethmuller, M.L. (2007). Particle Image Velocimetry in Lung Bifurcation Models. In: Particle Image Velocimetry. Topics in Applied Physics, vol 112. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73528-1_5
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DOI: https://doi.org/10.1007/978-3-540-73528-1_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-73527-4
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