Skip to main content
SpringerLink
Log in

Rezeptoren des Immunsystems

  • Chapter
Immunbiologie

Part of the book series: Springer-Lehrbuch ((SLB))

  • 6144 Accesses

Abstract

Eine wesentliche Eigenschaft des Immunsystems besteht in der Erkennung von Selbst und Nicht-Selbst, d.h. von körpereigen und körperfremd, sowie der Eliminierung letzterer. Hierfür haben sich im Laufe der Evolution Erkennungsstrukturen (Rezeptoren) entwickelt, die zellgebunden oder auch löslich vorliegen können. Dieses Kapitel beschreibt die wesentlichen Gruppen von Rezeptoren der angeborenen und erworbenen Immunität, mit besonderem Fokus auf Mustererkennungsrezeptoren, der Entstehung von Antikörper- und T-Zell-Rezeptoren, sowie der Bedeutung von MHC kodierten Peptidrezeptoren.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 64.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Spezielle Literatur

  • Bhalla A, Stone PR, Liddell HS, Zanderigo A, Chamley LW (2006) Comparison of the expression of human leukocyte antigen (HLA)-G and HLA-E in women with normal pregnancy and those with recurrent miscarriage. Reproduction 131:583–589

    Article  PubMed  CAS  Google Scholar 

  • Bogue M, Roth DB (1996) Mechanism of V(D)J recombination. Curr Opin Immunol 8:175–180

    Article  PubMed  CAS  Google Scholar 

  • Bonneville M, Saulquin X (2005) T-cell Receptors. Nature encyclopedia of life sciences 1–7

    Google Scholar 

  • Borrego F, Masilamani M, Marusina AI, Tang X, Coligan JE (2006) The CD94/NKG2 family of receptors: from molecules and cells to clinical relevance. Immunol Res 35:263–278

    Article  PubMed  CAS  Google Scholar 

  • Carroll MC (2004) The complement system in regulation of adaptive immunity. Nat Immunol 5:981–986

    Article  PubMed  CAS  Google Scholar 

  • Claire M, Labris JD (2005) Complement. Nature encyclopedia of life sciences 1–9

    Google Scholar 

  • Crotzer VL, Blum JS (2005) Autophagy and intracellular surveillance: Modulating MHC class II antigen presentation with stress. Proc Natl Acad Sci USA 102:7779–7780

    Article  PubMed  CAS  Google Scholar 

  • Dutronc Y, Porcelli SA (2002) The CD1 family and T cell recognition of lipid antigens. Tissue Antigens 60:337–353

    Article  PubMed  CAS  Google Scholar 

  • Falk K, Rotzschke O, Rammensee, H-G (1990) Cellular peptide composition governed by major histocompatibility complex class I molecules. Nature 348: 248–251

    Article  PubMed  CAS  Google Scholar 

  • Fritz JH, Ferrero RL, Philpott DJ, Girardin SE (2006) Nod-like proteins in immunity, inflammation and disease. Nat Immunol 7:1250–1257

    Article  PubMed  CAS  Google Scholar 

  • Groothuis TA, Neefjes J (2005) The many roads to cross-presentation. J Exp Med 202:1313–1318

    Article  PubMed  CAS  Google Scholar 

  • Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB (2005) CD1 assembly and the formation of CD1-antigen complexes. Curr Opin Immunol 17:88–94

    Article  PubMed  CAS  Google Scholar 

  • Lanzavecchia A, Sallusto F (2007) Toll-like receptors and innate immunity in B-cell activation and antibody responses. Curr Opin Immunol 19:268–274

    Article  PubMed  CAS  Google Scholar 

  • Leinders-Zufall T, Brennan P, Widmayer P, PC S, Maul-Pavicic A, Jager M, Li XH, Breer H, Zufall F, Boehm T (2004) MHC class I peptides as chemosensory signals in the vomeronasal organ. Science 306:1033–1037

    Article  PubMed  CAS  Google Scholar 

  • Lieber M (2001) Immunoglobulin gene rearrangements. Nature encyclopedia of life sciences 1–6

    Google Scholar 

  • Linehan SA, Martinez-Pomares L, Gordon S (2000) Mannose receptor and scavenger receptor: two macrophage pattern recognition receptors with diverse functions in tissue homeostasis and host defense. Adv Exp Med Biol 479:1–14

    Article  PubMed  CAS  Google Scholar 

  • McKenzie EJ, Taylor PR, Stillion RJ, Lucas AD, Harris J, Gordon S, Martinez-Pomares L (2007) Mannose receptor expression and function define a new population of murine dendritic cells. J Immunol 178:4975–4983

    PubMed  CAS  Google Scholar 

  • Meri S, Jarva H (2001) Complement regulatory proteins. Nature encyclopedia of life sciences 1–8

    Google Scholar 

  • Meylan E, Tschopp J, Karin M (2006) Intracellular pattern recognition receptors in the host response. Nature 442:39–44

    Article  PubMed  CAS  Google Scholar 

  • Monu N, Trombetta ES (2007) Cross-talk between the endocytic pathway and the endoplasmic reticulum in cross-presentation by MHC class I molecules. Curr Opin Immunol 19:66–72

    Article  PubMed  CAS  Google Scholar 

  • Olson R, Dulac C, Bjorkman PJ (2006) MHC homologs in the nervous system – they haven’t lost their groove. Curr Opin Neurobiol 16:351–357

    Article  PubMed  CAS  Google Scholar 

  • O’Neill LA, Bowie AG (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7:353–364

    Article  PubMed  CAS  Google Scholar 

  • Penn DJ (2005) Major Histocompatibility Complex (MHC). Nature encyclopedia of life sciences 1–8

    Google Scholar 

  • Robinson MJ, Sancho D, Slack EC, LeibundGut-Landmann S, Reis e Sousa C (2006) Myeloid C-type lectins in innate immunity. Nat Immunol 7:1258–1265

    Article  PubMed  CAS  Google Scholar 

  • Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich, HA, Arnheim N (1985): Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230: 1350–1354

    Google Scholar 

  • Saper MA, Samraoui B, Bennett WS, Strominger JL, Wiley DC (1987). Structure of the human class I histocompatibility antigen HLA-A2. Nature 329: 506–512

    Article  PubMed  Google Scholar 

  • Sandberg JK, Glas R (2005) Antigen processing. Nature encyclopedia of life sciences 1–7

    Google Scholar 

  • Sharon N (2007) Lectins: carbohydrate-specific reagents and biological recognition molecules. J Biol Chem 282:2753–2764

    Article  PubMed  CAS  Google Scholar 

  • Snell GD, Dausset J, Nathenson S (1976) Histocompatibility. Academic Press, New York 401

    Google Scholar 

  • Stockinger B, Veldhoen M (2007) Differentiation and function of Th17 T cells. Curr Opin Immunol 19:281–286

    Article  PubMed  CAS  Google Scholar 

  • Udono H, Wang JO, Watanabe T (2007) Antigen presentation to lymphocytes. Nature encyclopedia of life sciences 1–8

    Google Scholar 

  • Watts C (2004) The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules. Nat Immunol 5:685–692

    Article  PubMed  CAS  Google Scholar 

  • Zinkernagel RM, Doherty PC (1974) Restriction of in vivo T-cell mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 248:701–702

    Article  PubMed  CAS  Google Scholar 

Download references

Editor information

Editors and Affiliations

  1. Abteilung Immunbiologie, Universität Bonn, Römerstr. 164, 53117, Bonn, NRW, Deutschland

    Jürgen Neumann

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2008). Rezeptoren des Immunsystems. In: Neumann, J. (eds) Immunbiologie. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72569-5_2

Download citation

Publish with us

Policies and ethics

Search

Navigation