Abstract
Full-thickness macular holes are associated with corresponding markedly increased intensity in autofluorescence (Fig. 18.1) [5, 7, 15, 23]. In the absence of neurosensory retina, there is also no luteal pigment. Hence, the excitation and emission light can directly pass to and from the uncovered retinal pigment epithelium (RPE). The affected area also corresponds well to hyperfluorescence seen with fluorescein angiography. By optical coherence tomography, the edges of the macular hole are often upturned, presenting an increased thickness for the excitation light to pass through, which may explain the decreased autofluorescence intensity sometimes seen surrounding the hole. The attached operculum in stage 2 macular holes and the preretinal operculum in stage 3 macular holes show a focally decreased autofluorescence from blocking.
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(2007). Miscellaneous. In: Holz, F., Spaide, R., Bird, A., Schmitz-Valckenberg, S. (eds) Atlas of Fundus Autofluorscence Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71994-6_18
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DOI: https://doi.org/10.1007/978-3-540-71994-6_18
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